G-protein coupled receptor steps

Question 1

What are the steps to the G-protein coupled receptors (GPCR)?

Answer 1

1. signaling molecule binds to GPCR
2. GTP binds Gsa through exchange with GDP
3. Gsa detaches from GPCR
4. Gsa binds to AC
5. AC converts ATP to cAMP
6. cAMP activates PKA in cytosol
7. PKA phosphorylates other enzymes to activate or inactivate

Question 2

What metabolisms does insulin cascade result in? (5)

Answer 2

1. influx of glucose into cell via translocation of GLUT4
2. glycogen synthesis
3. glycolysis
4. inhibition of gluconeogenesis
5. fatty acid synthesis