Future Genetics

Question 1

What is analytic validity?

Answer 1

accuracy of the test

Question 2

What is clinical validity?

Answer 2

ability of test to predict outcome

Question 3

What is clinical utility?

Answer 3

ability of test to improve outcome if used

Question 4

What is ACCE model for evaluating genetic tests?

Answer 4

ACCE - 
Analytical validity
Clinical validity
Clinical Utility
Ethical implications.

Question 5

Are most genetic tests FDA approved?

Answer 5

no

Question 6

What is the main resource for genetic test info?

Answer 6

NIH genetic testing registry

Question 7

What is expression profiling?

Answer 7

array based techology that assesses RNA levels and interprets patterns that are associated with pathologies.

Question 8

What are companion diagnostics?

Answer 8

diagnostic to test and see if targeted therapies will be effective.

Question 9

What is Direct to consumer testing (DTC)?

Answer 9

genetic testing to provide risk assessment, diagnosis or drug response. Web based companies collect DNA and report risks based off it. Not FDA approved or regulated at all.