Fungi Flashcards
What is found in the cell membrane and cell wall of fungi
membrane- Ergosterol, B glucans (instead of cholesterol)
Wall- Chitin (instead of poludoglycan like in bac)
What do echinocandins antifungals do
Inhibits enzyme that synthesizes b glucans
What do polyenes antifungals do
Bind to ergosterol and weaken the membrane
What do azoles + allylamines antidungals do
inhibit enzyme that synthesizes ergosterol
How do fungi gain nutrients
Aquire thru absorbtion
-Hyphea secrete enzymes that decompse surroundings so that they can absorb
What are saprobes fungi
absorb nutrients from dead organic material
what are the types of pathogenic fungi
- filamentous molds
- yeasts
- dimorphic
what is a filamentous mold
Multicellular with branching hypae
How do filamentous molds reproduce
Reproduce thru asexual spores (dispersed thru winds)
What is a yeast + how do they reproduce
unicellular oval or round cells
reproduce thru budding
what are dimorphic fungi (and what are they divided into)
Fungi that are able to convert from hyphal to yeasts
Themal and non thermal varients
When does dimorphic fungi change from filamentous form to yeast form
filamentous when grown at 22degrees
yeast when grown at 37 degrees
What are the clinical classifications of fungi
- superficial
- cutaneous
- subcutaneous
- endemic
- oportunistic
Where are superficial mycoses found
confined to superficial layers of the skin
Where are cutaneous mycoses found
Involve the skin, nail or hair tissue
