Fungal Diseases Flashcards
1
Q
What are they key structural aspects of a fungi?
A
- unicellular or multicellular
-Composed of polysaccharides/ proteins/ lipids and pigment
2
Q
How is cryptococcus (fungal disease ) transmitted?
A
- inhaled
3
Q
How does cryptococcus reproduce?
A
- mitosis
4
Q
What immune responses occur during cryptococcus?
A
- compliment activation - increases phagocytosis
- cell mediated immunity
5
Q
How does cryptoccus evade the immune response?
A
- antioxidants such as melanin produced
- inhibit damaging reactive oxygen species
6
Q
How does ringwork survive in the environment?
A
- highly resistant in the environment
- zoonotic
- can survive for months or years
- resistant to freezing
- contagious
7
Q
What are the symptoms of ringworm?
A
- hairloss raised red areas
- dermatophytes feed on keratin in the skin
8
Q
What is the immune response to ringworm?
A
- cell mediated immunity
- Th1 cells
- cytotoxic effects of CD4 and CD8 cells
-antibodies = damaged fungal pathogens / neutralising antibodies on initial interaction
9
Q
A
