From RNA to Protein Flashcards

1
Q

Stop codons

A

UAG
UAA
UGA

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2
Q

!!!!

A

Methionine ve tryptophan sadece bir kodla sentezlenir
Diğerleri Birden fazla

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3
Q

Synonymous

A

Codons specifying the same aa
İlk iki nükleotit aynı üçüncüsü farklı

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4
Q

!!!!

A

Genetic code lacks punctuation
Genetic code is non-overlapping
——DNA dizilimi aynı ama biz üç farklı şekilde okuyabiliriz bunu methionine belirler

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5
Q

Open reading frame(ORF)

A

Wobble:bir baz birden fazla baz ile hidrojen köprüsü yapabilir
tRNA nın uzun ucu:3’
Kısa ucu:5’

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6
Q

Ribozomda bağlanma bölgesi

A

Soldan sağa:::E-P-A
E: exit site
P: peptidyltRNA
A: aminoacyl-tRNA

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7
Q

aminoacyltRNA synthetases

A

Enzymes that attach aa to tRNA
Her trna sentezi bir aa özgü

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8
Q

TRNA yapısı

A

Uzun üst:3’
Kısa üst:5’
Sağ:tethers Trna /rna yı bağlar
Sol: D loop/tanımak

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9
Q

Translations

A

Initiation IF1-IF2-IF3
Elongation
Termination

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10
Q

Start codon for translation

A

Prokaryotes:Shine-Dalgarno Sequence
Eukaryotes:Kozak consensus sequence

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11
Q

Translation cycle

A

Gtp ve release faktörler bağlanır sentezlenen proteini atar
—-releasing factor 1:UAA-UAG
—-releasing factor 2:UAA-UGA

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12
Q

Note !!!

A

Prokaryotlarda translations transcription durmadan başlar

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13
Q

mRNA Structure for translations

A

Cylic /ends closed with each other
Bu yapı aynı proteini defalarca sentezlememizi sağlar
Ribozom mRNA neredeyse oraya gider

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14
Q

Propfreading

A

Checking and correction of errors in transcription

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15
Q

!!!!!

A

RNA is synthesized from non-coding DNA template

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16
Q

Nucleases

A

Fosfodiester bağlarını kırarlar
Endonuclease:it can break Dna from control sites
Exonuclease:it can break Dna from end sites profreading için gerekli!!