From Quiz 4- Bone, Joint, and SKM

Question 1

histological hallmark for Paget’s is

Answer 1

mosaic pattern of lamellar bone

Question 2

osteopetrosis characterized by

Answer 2

hypermineralization of bone

Question 3

on x-ray aneurysmal cyst reveals

Answer 3

honey-combed appearance

less symmetry to shape of cyst

Question 4

Gross examination of an osteoid osteoma is characterized by

Answer 4

an area of gritty, cherry red tissue, surrounded by dense sclerotic bone

Question 5

skip lesions within bone

Answer 5

osteosarcoma

Question 6

microscopically fibrosarcoma appears as

Answer 6

sheets of spindle shaped cells

Question 7

x-ray of osteoarthritis shows

Answer 7

jnt space narrowing
osteophyte formation (bony outgrowths)
subchondral bone cysts
sclerosis

Question 8

which lab IS highly specific for RA?

Answer 8

anti-CCP

Question 9

what x-ray finding is characteristic for ankylosing spondylitis?

Answer 9

“bamboo spine”

Question 10

the number one cause of septic arthritis (aka supperative arthritis) in adults?

Answer 10

staphylococcus

Question 11

pseudogout caused by

Answer 11

calcium pyrophosphate crystals

Question 12

the most common forms of muscular dystrophy

Answer 12

Duchenne’s

Question 13

Duchenne’s is due to a defective gene on the X chromosome that leads to an inability to produce which protein?

Answer 13

dystrophin

Question 14

Myasthenia gravis is caused by

Answer 14

Abs that block Ach receptors

Post-synaptic

Question 15

thymoma is a rare tumor of the thymus gland associated with which condition?

Answer 15

Myasthenia gravis

Question 16

Lambert-Eaton syndrome is caused by

Answer 16

Abs that block calcium channels

pre-synaptic

Question 17

The biopsy appearance of inclusion body myositis is characterized by

Answer 17

focal areas of WBCs that invade muscle cell
vacuoles
amyloid-related protein
inclusions

Question 18

the most common soft tissue tumor in children

Answer 18

Rhabdomyosarcoma

Question 19

B and T cells

perifascicular muscle fiber atrophy

Answer 19

dermatomyositis

Question 20

cells with a single, 
round or oval nucleus, 
size and 
appearance somewhat 
resembling lymphocytes

Answer 20

Ewing sarcoma