From Quiz 3- Endocrine Flashcards
most frequent type of functioning pituitary adenoma
prolactinoma
granulomas found with this condition
De Quervain’s thyroiditis
a type of cancer that is encapsulated
Follicular adenoma
The fronds of tissue have thin fibrovascular cores
Papillary carcinoma
psammoma body
Papillary carcinoma
excess amounts of calcitonin being detectable in the serum
Medullary carcinoma
undifferentiated malignant cells
Anaplastic carcinoma
1 cause of hypercalcemia in outpatient setting
parathyroid adenoma
Lab profile of Addison’s disease:
hyperkalemia
second most common reason for primary hyperparathyroidism
hyperplasia
these tumors usually secrete excess parathyroid hormone, thereby producing hyperparathyroidism and hypercalcemia.
parathyroid carcinoma
PTHrP can be secreted by many types of cancer cells but is seen most commonly with
lung cancer
why do you see hyperpigmentation with primary addison’s but not secondary?
primary is due to dysfunction of adrenals with high ACTH (ACTH stimulates melanocytes to produce more melanin)
secondary is due to inadequate secretion of ACTH by the anterior pituitary so no excess stimulation of melanocytes takes place
with 21-hydroxylase deficiency, which hormones will be deficient?
cortisol
aldosterone
Cushing’s disease shows excess what? clinical manifestation?
- excess ACTH (at pituitary NOT level of adrenals)
- incr cortisol
- hyperglycemia
