Fragility Fractures Flashcards
What are fragility fractures?
Fracture resulting from a simple fall, at standing height or less
(a normal human skeleton should withstand such a force and therefore such an injury is a diagnostic indicator of possible osteoporosis (or other pathological condition of bone))
What are the 5 common osteoporotic fractures?
Vertebral body Distal radius Neck of femur Neck of humerus Pubic ramus
(any possible - low energy trauma)
Name 5 high energy fractures of young adults that are also seen now as fragility fractures
Femoral shaft
Elbow (distal humerus, prox forearm)
Knee (distal femur, proximal tibia)
Ankle (bimalleolar and trimalleolar)
Cervical spine
What would be in a differential diagnosis for fragility fractures?
(someone presents with a fragility fracture what would you consider being a cause?)
Osteomalacia
Tumour
Other conditions
-e.g. Paget’s disease, osteogenesis imperfecta etc
Back pain
-Always rule out infection and tumour
What is the difference in bone weakness between osteomalacia and osteoporosis?
Osteomalacia
-Qualitative bone weakness
Osteoporosis
-Quantitative bone weakness
Are bone tumours more commonly primary or secondary?
Metastatic 25x commoner than primary malignant, but rare distal to elbow or knee
What is the commonest osteoporotic fracture?
Vertebral Compression Fracture (VCF)
-half of all osteoporotic fractures
What is the most common location for a vertebral compression fracture in osteoporosis?
Thoracic vertebra
wedge fracture
What deformity does vertebral fracture in osteoporosis cause?
kyphotic deformity of thoracic spine
“Dowager’s spine”
After the first vertebral compression fracture what is the risk of a subsequent VCF?
After first VCF, risk of subsequent VCF increases by more than 5-fold
What are the clinical features of Vertebral compression fracture acutely?
Sudden onset of back pain with little or no trauma
e.g. bending, turning, coughing
What are the clinical features of vertebral compression fracture chronically?
Spinal deformity - kyphosis
“Dowager’s hump”
Loss of height
Protuberant abdomen
-loss of appetite
Chronic pain, possible nerve root entrapment
What aspect of vertebral compression fracture effects mortality?
VCF reduces pulmonary function
- One thoracic VCF causes 9% loss of FVC
- One thoracic VCF makes another 5x more likely so downward spiral
-Lung function (FVC, FEV1) is significantly reduced in patients with thoracic and lumbar fracture
How do you treat VCFs?
Treat the osteoporosis
-Commenced on drug therapy regardless of T-score
Symptomatic (analgesia)
-Avoid bed rest and braces/supports (only weaken bone and muscle further)
(future? -> surgery: correct deformity by vertebroplasty or kyphoplasty, strengthen with artificial bone substitute or bone cement)
What is the second most common osteoporotic fracture?
Wrist
-Colles’ fracture