Fractures, Osteonecrosis, Osteomyelitis Flashcards

1
Q

The bone fractures after repeated extra stress, i.e., there were some tiny microfractures (as in osteoporosis)

A

stress fracture

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2
Q

The bone is cracked, but not broken into two pieces

A

incomplete fracture

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3
Q

What is a greenstick fracture?

A

incomplete fracture in kids that results from impact to thier “supple” long bones

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4
Q

closed fracture

A

overlying tissue is in fact

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5
Q

The bacteria have a route from the surface to the bone; perhaps the bone is even sticking out the wound.

A

compound, open fracture

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6
Q

The bone is broken into several pieces.

A

multifragmented (comminuted) fracture

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7
Q

A curious term for a fracture in which the ends of the bone fragments have done serious damage to the surrounding tissue.

A

complex fracture

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8
Q

Due to intrinsic disease of the bone; the force would not have broken a normal bone. Seen in osteoporosis, cancer, osteogenesis imperfecta.

A

pathologic fracture

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9
Q

Describe the process of callus formation after a bone fracture

A
  1. bleeding and formation of clot
    • devascualrization of edges of fractured/dead bone
  2. recruitment and ingrowth of neovascualization
  3. fibroblasts organize clot
  4. removal of dead cortex
  5. ingrowth of osteocytes
  6. new/woven bone formation
  7. cartilage produced at surface of callus
  8. continued remodeling (over months)
  9. complete bone healing (loss of cartilage cap)
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10
Q

T or F: the fractured ends of bone must be perfectly aligned to begin the process of healing/callus formation

A

F: but they must be in close proximity

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11
Q

What happens if the fractured ends of a bone are not in close enough proximity for healiing?

A

the callus cannot form an there is a “fibrous nonunion” of the ends
= fibrous replacement of tissue between the ends

**pathologic

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12
Q

Microscopically, during bone healing, fractured bony spicules are being joined together by…

A

new osteiod

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13
Q

Why are metal pins surgically inserted after some fractures?

A

to produce the conditions necessary for appropriate callus formation and bone healing.

= align the ends

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14
Q

Where on the bone does osteonecrosis most likely occur?

A

convex surface of joints

*usually spares the synovium/joint space

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15
Q

What is the feared result of osteonecrosis

A

detachment of the articular cartilage

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16
Q

osteonecrosis can be a complication of what 3 conditions?

A
  1. femoral neck fracture or disslocation
  2. sickle cell
  3. decompression sickness
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17
Q

Osteonecrosis has a mysterious link to..

A

alcohol abuse and glucocorticoid use

18
Q

How can sickle cell disease lead to osteonecrosis?

A

sickled RBCs occlude vessel

hypercellularity of the marrow can interfere with normal blood flow in the marrow

19
Q

soft tissue swelling with periosteal new-bone formation and a moth-eaten lytic process

A

hand foot syndrome

*seen in sickle cell dz

20
Q

XR manifestation of bone with chronic infarcts and secondary osteoarthritis (seen in sickle cell)

A

irregular sclerosis and lucency (infarcts)
bone-in-bone appearance (infarcts)

narrowed cartilage and irregular joint surfaces (OA)

21
Q

Bone within bone appearance on XR can indicate

A
  • **sclerosis, resulting from multiple infarctions

* think sickle cell dz

22
Q

osteomyelitis is caused by ___ organisms that spread

A

pyogenic
*most commonly staphylcoccus (80-90%)

that spread hematogenously, contiguously, or in pts with vascualr insufficiency

*hematogenous is most common in kids

23
Q

What are risk factors for developing osteomyelitis

A
DM 
periph vascualr dxz
sickle cell 
congenital phagocyte function defect 
presence of foreign materials
ortho surgery 
adjacent infections
24
Q

TB osteomyelitis

Name of dz?
what bones are affected?

A

Pott Dz

vertebrae (causes collapse –> kypohosis)

25
What organism is assc with osteomyelitis in sickle cell pts
salmonella
26
Mixed bacterial osteomyelitis is assc with
trauma or surgery
27
congenital syphilitic osteomyelitis is assc with
saber shins and saddle nose mom passes syphillis to fetus
28
chronic osteomyelitis can give rise to
squamous cell carcinoma
29
On what part of the bone does osteomyelitis typically begin
metaphysis | spreads internally and externally from here +/- sinsus tracts
30
sinus tracts in bone
osteomyelitis
31
In chronic osteomyelitis what is happening outside the bone and inside the bone at the site of infection?
outside = bone growth = reactive = involucrum inside = bone necrosis = partial reabs = sequestration
32
subperiosteal shell of viable new bone
involucrum *chronic osteomyelitis
33
inner necrotic cortex
sequestrum *chronic osteomyelitis, necrosis is purulent
34
empty lacunae in spicules implies
dead bone
35
T or F: poly predominant in CHRONIC osteomyelitis
T | NO LYMPHOCYTES present
36
What immune cells are present in acute osteomyelitis? Chronic?
neutrophils! NO lymphocytes prob some fibroblasts and maybe macrophages too
37
marked ulceration and necrosis of calcaneus
osteo in DM
38
spinal tuberculosis is a combined infectious of
vertebral bodies (spondylitis) and joint spaces (spondylarthritis)
39
gibbus deformity
severe kyphosis from vertebral collapse * can be seen with Pott Dz
40
manifestation of primary syphillis
chancre = skin lesion at point of contact (usually genitals or anus) *can last 4 to 6 weeks and heals spontaneously
41
manifestation of secondary syphillis
- 1-6 mos after primary - Chondylomata lata: symmetrical reddish-pink non-itchy rash on the trunk and extremities (can be on palms and soles) that contain ACTIVE treponeme = CONTAGIOUS
42
manifestations of tertiary syphillis
-1-10 years after primary - gummas = chronic soft, tumor like granulomas due to the immune sys inability to clear the org - -> chronic infalm state - neuropathic joint dz = degeneration of joint surfaces --> loss of sensation and fine position sense (proprioception) - neuro syphillis - CV syphillis Nolan Never Gets Cold bc he has the syph