fourth-MKSAP

Question 1

Measuring serum _____alone is sufficient to monitor thyroid replacement therapy except in _____, for which free thyroxine measurement is the laboratory test of choice

Answer 1

TSH

central hypothyroid

Question 2

___ can cause GNRH disruption of secretion and in turn amenorrhea

Answer 2

low calorie/severe calorie restricition
intense exercise
low body weight

Question 3

in familial hypocaliuric hypercalcemia, the calcium-creatinine clearance ratio is ____

Answer 3

less than 0.01

Question 4

in familial hypocaliuric hypercalcemia, there is mutation ____

Answer 4

in the CaSR gene

Question 5

what electrolytes shold be monitoredin hypoparathyroidism

Answer 5

P because it is not cleared in the kidneys due to low pth
-may need P binders

Ca by hypocalcemia

Question 6

in pcos, testosterone and DHEA are both

Answer 6

elevated

Question 7

after male semen analysis has ruled out cause for lack of conception, ___ test is FIRST STEP for female should be done

SECOND STEP?

Answer 7

first: midluteal phase serum progesterone level

Second: assess fallopian/uterine patency with Hysterosalpingography

Question 8

after trying to concieve ___ time without success, infertility is the diagnosis

Answer 8

1year

Question 9

initial test for pheochromocytoma?

Second test?

Answer 9

initial: plasma free metanephrine

second: adrenal imaging

Question 10

in osteomalacia, lab value (high/low)_____ of this ___ typically precedes low levels of ___ and _____

Answer 10

HIGH, alk phos

Ca,P

Question 11

in hyperprolactenemia, ___ thyroid dysfunction is seen

pathophysiology

Tx (in this case with the thyroid issue)

Answer 11

hypothyroidism

TRH stimulates release of TSH aaand Prolactin

Tx: fix the hypothyroidism and recheck prolactin levels after

Question 12

MCC hyperprolactenemia

Answer 12

Normal physiological is MCC:

pregnancy, lactation from nipple stimulation
sexual intercourse
sleep

Question 13

MCC non-tumor cause of PATHOLOGICAL hyperprolactinemia

Answer 13

meds (NOT Hypothryroidism)

Question 14

what is the FIRST disease to screen if a patient has concerning adrenal mass?

Answer 14

pheochromocytoma

Question 15

what size of adrenal mass warrants referral to endocrinologist for adrenalectomy?

Answer 15

> 4cm

Question 16

what housefield units of adrenal mass warrants referral to endocrinologist for adrenalectomy?

Answer 16

> 20

or

11-20 with >4cm mass