first-MKSAP Flashcards
screening test for acromeg
insulin like growth factor
how to tell apart ectopic cushings vs pituitary tumor cushings
8mg Dexa suppression test
-if cortisol brought down by at least 50% or more->PITUITARY
-if cortisol still up->ECTOPIC (ie lung/renal)
confirmatory test for acromeg
if elevated ILGF–>CONFIRM with oral gluc tolerance
tx for primary aldosteronism caused by idiopathic hyperaldosteronism (imaging ruled out any adrenal masses)
spirono
labs for klienfelters
Confirmatory diagnosis
Tx
Labs: elevated fsh and lh
low testosterone
confirm with gnetic testing: karyotype
(XXY)
Tx with testosterone
diagnosis criteria for gestational diabetes
as in, it MUST be diagnosed ___ time in pregnancy
Diabets at 2nd or 3rd trimester pregnancy WITHOUT pre-pregnancy diagnosis
HOW to diagnose gestational diabetes
Oral glucose tolerance test
klinefelter phenotype
micropenis
small firm testes
gynecomastia
Tall
decrease muscle mass/decr sexual hair/erectile dysfunction
acromegaly likely to have ___ vital sign
HTN
non-tumor cause of hyperprolactinemia
Meds: dopamine antagonists
Reglan
antipsychotics
mediation induced hyperprolactenemia tends to have prolactin levels ___
(and non-med induced has ___)
> 200…….normal <15
(25-100 in non med hyperprolactinemia)
Tx for non-med induced hyperprolactinemia
moa?
CABERGOLINE
moa-dopamine agonist
Tx for med induced hyperprolactinemia in a female ptnt
estrogen progesterone replacement
First-line diagnostic tests for Cushing syndrome **************
two of three tests must be abnormal:
- overnight low-dose dexamethasone suppression test
- 24-hour urine free cortisol measurement
- late-night salivary cortisol measurement;
THEN ACTH
