Forensic plant Poisoning Flashcards
Datura stramonium poisones parts ?
flowers/ stem/ fruit/
leaves/roots
Fatal dose: 50-75 seeds
Datura stramonium poisoning substances ?
atropine, hyoscine and hyoscyamine
Datura stramonium symptoms ?
Dryness of mouth
Dysphagia
Dysarthria
Diplopia
Autopsy findings
Seeds in stomach
& non specific
features
Dry hot and red skin
Drowsiness leading to coma
Urinary retention
Death : respiratory failure or cardiac
arrhythmia
Pagiyantha dicotoma poisones parts ?
Most poisonous / latex/
fruit/ seeds
Pagiyantha dicotoma poisones substances ?
alkaloids/ strychnine
Pagiyantha dicotoma symptoms ?
White latex : inflammation of eye
Ingestion : dryness of mucus
membranes, thirst, dilataiton of
pupils, rapid pulse, psychomotor
disturbances, hallucinogenic
effects.
Accidental poisonin
Suicidal poisoning
Strychnos nux vomica poisones parts ?
Seed
(although all parts toxics)
Fatal dose: 1-2 seeds
Strychnos nux vomica poisones substances ?
alkaloids ( strychnine/ brucine)
Strychnos nux vomica symptoms ?
Bitter taste
Clnoic (intermittent ) &Tonic
(sustained) seizers
Affects flexor and extensor muscles
simultaneously
Facial Muscles : “risus sardonicus” ,
“trismus”(locked jaw)
Opisthotornus
Respiratory distress and death
Agonizing death because of
consciousness
Cerbera manghas poisones parts ?
Fruit
Kernal
Fatal dose: 2 fruits
Cerbera manghas toxines ?
glycocides ( Cerberin/ odollum and thevetin)
Cerbera manghas symptoms
Burning sensation and dryness of the mouth,
nausea, vomiting, diarrhoea and abdominal
pain are early features.
CVS – Bradycardia, hypotension, 1
st and 2
nd
degree heart block atrial and ventricular
extrasystoles, ventricular fibrillation. (ECG
Changes)
Convulsions and coma
Thevetia peruviana poisonous parts ?
Most poisonous:
Fruit /seed/ all
parts of tree
Fatal dose: 2 seeds
Thevetia peruviana toxines ?
Cardiac glycosides, Thevetin A & Thevetin B.
Thevetia peruviana signs and symptoms ?
nausea and vomiting due t
irritant effect of the stomac
Vomiting 6 to 12 hours
ingestion implies signific
absorption of the toxin.
Cardio-toxicity caus
bradycardia, varying degrees of Atropine
heart block and hypotension
Nerium oleander poisones parts ?
Most poisonous: Pod/seed/
all parts of tree
Nerium oleander toxins ?
Cardiac glycosides (oleandrin, nerin )
Gloriosa superba poisonous parts ?
Most poisonous: tubers/
all parts of the plant
Fatal dose: 10g tubers
Gloriosa superba toxins ?
Toxin: Alkaloid Colchicine, Gloriosine, Superbine
Gloriosa superba symptoms ?
SIGNS & SYMPTOMS OF NIYAGALA POISONING
Autopsy findings hemorrhagic
Dehydration
Hypovolaemia,
hypotension, shock
GI features:
features in stomach,
intestines, heart, lung, kidney
Toxic 6 to 12
hours of
ingestion.
Niyagala
Poisoning
abdominal pain,
Nausea, Vomiting,
Diarrhoea with blood
Death
Resolve
Granulocytopenia, thrombocytopenia,
clotting defects, bleeding Late
Cardic arrythmias, hepatic ,renal
and respiratory failure, DIC
Effects on mitosis:
alopecia
Jatropha curcas poisonuos parts ?
Fatal dose:2 seeds cause purging
Jatropha curcas toxines ?
Toxalbumin Curcin
Jatropha curcas symptoms
nausea, vomiting, epigastric and abdominal pain and
diarrhoea resulting in dehydration, electrolyte
imbalance, cramps and shock.
Other features of poisoning are hypoglycaemia,
retinal haemorrhages, haematuria, convulsions, and
shock. Hepatic necrosis and acute renal failure have
been reported
Ricinus communis poisonous parts ?
Most poisonous: seeds/plant
Fatal dose: 1 seeds
Ricinus communis toxins ?
Toxin: alkaloid Ricinin & toxalbumin Ricin
Ricinus communis symptoms ?
Symptoms seen after 3 to 20 h
Abdominal pain, emesis, diarrhea with or without
blood, muscular pain
cramps in the limbs, circulatory collapse, dyspnoea
and dehydration
Late features: liver and kidneys dysfunction
injected ricin: pain at the injection site, muscular
necrotizing,
Autopsy: haemorrhagic necrosis in intestines and
heart and oedema in lungs
Ricinus communis symptoms
Symptoms seen after 3 to 20 h
Abdominal pain, emesis, diarrhea with or without
blood, muscular pain
cramps in the limbs, circulatory collapse, dyspnoea
and dehydration
Late features: liver and kidneys dysfunction
injected ricin: pain at the injection site, muscular
necrotizing,
Autopsy: haemorrhagic necrosis in intestines and
heart and oedema in lungs
