Fluid & Electrolytes Part 3 Flashcards
Homeostasis of Hydrogen (H+) concentration in body fluids =
Acid Balance
When a hydrogen imbalance occurs, what happens?
The H+ shifts between the intracellular & extracellular compartments to compensate for the imbalance
A minor hydrogen change can have major effects on-
Cellular Function
For optimal cell function, we need a steady balance of -
Acids & Bases
Used to evaluate acid-base balance =
Arterial Blood Gas (ABG)
This is an indirect measurement of H+ ion concentration =
Arterial pH
What is the arterial pH a result of?
Respiratory & Kidney Compensation Function
What is your pH an expression of?
The balance between Carbon Dioxide (CO2) and Bicarbonate (HCO3)
CO2 is regulated by-
The Lungs
HCO3 is regulated by-
The Kidneys
The greater the H+ concentration =
The more acidic bodily fluids are and the lower the pH
The lower the H+ concentration =
More alkaline the bodily fluids are and the higher the pH
The normal pH of Arterial Blood (Serum) =
7.35 - 7.45
Whenever your pH is lower than 7.35 it is-
Acidosis
Whenever your pH is higher than 7.35 it is-
Alkalosis
What is Acidosis?
An increase in H+ ions
Lose base (Bicarbonate / HCO3)
What is Alkalosis?
A decrease in H+ ions
Gain base (Bicarbonate / HCO3)
When does death occur due to a poor pH?
Less than or equal to 6.8
Greater than or equal to 7.8
How do you treat an acid base imbalance?
You have to fix whatever the problem is that’s causing the acid base imbalance to fix the acid base imbalance
To maintain acid base balance, what are the 3 different bodily mechanisms to compensate for it?
Chemical Buffers (Carbonic Acid-Bicarbonate System)
Respiratory Regulation & Compensation
Renal Regulation & Compensation
How do the lungs impact the acid-base balance?
The lungs can release or retain acid
How does the Carbonic Acid-Bicarbonate System impact the acid-base balance?
It can send out chemical buffers to neutralize excess acid or excess base
How do the kidneys impact the acid-base balance?
They can either retain or excrete acids and bases
What are the chemical buffers and protein buffers that can be released to regulate acid-base balance?
Chemical Buffers = Bicarbonate & Intracellular Fluid
Protein Buffers = Albumin & Globulins