Fluid & electrolyte disturbances Flashcards

1
Q

hyponatremia- Sx

A
  • Nausea, malaise, HA, disorientation
  • Seizure
  • Coma
  • Brain damage
  • Resp arrest
  • Brainstem herniation
  • Often due to H2O inbalance rather than Na
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2
Q

hyponatremia- Dx

A
  • Serum electrolytes
  • creatinine,
  • osmolality,
  • urine sodium
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3
Q

hyponatremia- Tx

A
  • Restrict water
  • Isotonic fluids
  • Diuretics
  • Discontinue meds
  • Vasopressin antagonists
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4
Q

Hypernatremia- Sx

A
  • Orthostatic hypotension
  • Oliguria
  • Lethargy, irritability, weakness
  • hyperthermia, delirium, seizures, coma
  • May not be specific in elderly
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5
Q

Hypernatremia- Dx

A
  • Urine osmolality

- Serum osmolality

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6
Q

Hypernatremia- Tx

A
  • Correct fluid loss with dextrose & saline water over 48 hrs
  • Add K & phosphate as needed
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7
Q

Hypokalemia- Sx

A
  • Muscular weakness, muscle cramps
  • Hyporeflexia, hypercapnia, tetany, rhabdomyolysis
  • Hypertension
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8
Q

Hypokalemia- Dx

A
  • ECG- U waves
  • Serum & urine concentration
  • TTKG
  • Hypomagenesmia
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9
Q

Hypokalemia- Tx

A
  • Dietary to IV K

- Mg required to replete

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10
Q

Hyperkalemia- Sx

A
  • Abd distension & diarrhea
  • Musc weakness, flaccid paralysis, ileus
  • Cardiac arrythmias
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11
Q

Hyperkalemia- Dx

A
  • Plasma potassium
  • Creatinine, lytes
  • ABG
    ECG- peaked T waves
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12
Q

Hyperkalemia- Tx

A
  • Withhold K
  • Insulin, bicarb, beta agonists to shift K into cells
  • IV Ca++ to stabilize myocardium
  • Hemodialysis
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13
Q

Hypocalcemia- Sx

A
  • Extensive spasm- cramps & tetany
  • Laryngospasm with stridor
  • Covulsions, paresthesias, abd pain
  • Trousseau sign
  • Chvostek sign
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14
Q

Hypocalcemia- Dx

A
  • Serum calcium
  • Elevated serum phosphate
  • PTH
  • Low serum Mg
  • Vit D levels
  • ECG- Prolonged QT interval
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15
Q

Hypocalcemia- Tx

A
  • Calcium infusion over 4-6 h
  • Oral/ IV Ca++ carbonate
  • Vit D
    Thiazide diuretic to reduce renal loss
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16
Q

Hypercalcemia- Sx

A
  • GI, kidney & neuro fxn
  • Constipation & polyuria
  • N/V
  • Hematuria
  • Depression, stupor, lethargy
17
Q

Hypercalcemia- Dx

A
  • Serum & ionized Ca
  • Urine Ca
  • PTH
18
Q

Hypercalcemia- Tx

A
  • Establish euvolemia to induce renal excretion
  • dialysis
  • Bisphosphonates
19
Q

Hypophosphatemia- Sx

A
  • Resp failure
  • Encephalopathy
  • Arrhythmia
  • Anorexia
  • Fracture
  • Hemeolytic anemia- petechea
20
Q

Hypophosphatemia- Dx

A
  • Urine phosphate

- PTH

21
Q

Hypophosphatemia- Tx

A
  • Oral phoshate replacement
22
Q

Hyperphosphatemia- Sx

A
  • Symptoms of underlying disease
  • Extraosseous calcification of soft tissue/ vasculature
  • Acute kidney injury
  • Secondary hyperparathyroidism
  • Renal osteodystrophy
23
Q

Hyperphosphatemia- Dx

A

Serum phosphate

24
Q

Hyperphosphatemia- Tx

A
  • Tx underlying disorder
  • Calcium carbonate
  • Decreased intake- dairy, meats, processed foods
25
Q

Hypomagnesemia- Sx

A
  • Neuromuscular & nervous system hyper irritability
  • Termors
  • Babinski response
  • Nystagmus
  • HTN, tachycardia, ventricular arrhthymia
  • Weakness & cramping
26
Q

Hypomagnesemia- Dx

A
  • Serum magnesium
  • Urine excretion
  • Low PTH
  • Hypo kalemia, calcemia
27
Q

Hypomagnesemia- Tx

A
  • IV Mg sulfate
28
Q

Hypermagnesemia- Sx

A
  • Decreased DTR
  • Confusion & weakness
  • Mental obundation
  • Resp muscle paralysis, cardiac arrest
29
Q

Hypermagnesemia- Dx

A
  • Serum Mg

- Elevated- BUN, Serum creatinine, uric acid

30
Q

Hypermagnesemia- Tx

A
  • Calcium chloride as antagonist
31
Q

Hyponatremia w/ high plasma osmolality

A
  • Hyperglycemia
32
Q

Hyponatremia w/ normal plasma osmolality

A
  • Hyperlipidemia
  • Hyperproteinemia
  • Commonly due to lab error
33
Q

Hyponatremia w/ low plasma osmolality

A
  • Most common
  • Hypovolemia
  • Euvolemia
  • Hyper volemia
34
Q

Hyponatremia w/ low plasma osmolality- Hypovolemia

A

Thiazides, hypoaldosterone, renal salt wasting, V/D, blood loss, 3rd spacing

35
Q

Hyponatremia w/ low plasma osmolality- Euvolemia

A

Most common

  • SIADH
  • Hypothyroid
  • Adrenal insufficiency
  • primary polydipsia
36
Q

Hyponatremia w/ low plasma osmolality- Hypervolemia

A

HF, cirrhosis, liver failure, nephrotic syndrome