FLUID ELECTROLYTE AND ACID BASE Flashcards
State of Equilibrium
Stabilization of body functions and maintain normal status
Homeostasis
ECF Volume Deficit
Dehydration
ECF Volume Excess
Fluid Overload
Infant water content
70-80%
50-70% water content
Adult Male
Adult female water content
50-60%
Child water content
65-75%
Older Adult water content
45-55%
Doesn’t have a lot of fluid, more fats, easily dehyrated
Obesity
Water compartment of body
Intracellular Fluid
Extracellular Fluid
Transcellular Fluid
2/3 of fluid within cells
ICF
1/3 of fluid outside cell
ECF
2 ECF
Interstitial
Intravascular
Fluid in between cells (lymph)
Interstitial
Fluid within the blood vessels
Intravascular
Fluid in small and specialized cavities
Transcellular fluid
Fluid protects the spine
Cerebrospinal fluid
Fluid in lungs
Pleura
Fluid in GI Tracts
Peritoneum
Water content of the body
Plasma
Interstitial Fluid IF
Intracellular Fluid ICF
How many liters is in Plasma
3L
How many liters is in IF
10L
How many liters is in ICF
28L
Plasma has 55% and Formed elements is 45%
Blood
Component of Plasma
Protein 7%
Water 91%
Other Solutes 2%
Component of Proteins
Albumin 58%
Globulin 38%
Fibrinogen 4%
Components of Other Solutues
Ion
Nutrient
Waste Products
Gases
Regulatory Substance
Components of Formed Elements
Platelets 250-400 thou
WBC 5-9 thou
RBC 4.2-6.2 thou
Components of WBC
Neutrophils
Lymphocytes
Monocytes
Eosinophils
Basophils
Function of Body water
Stabilize body temp
Protection
Chemical Reactions
Transport
It allows to absorb and release large amounts of heat before changing temp
High heat capacity
Acts as a lubricant or cushion
Protection
Chemical Composition of water
H2O
Has 1 + only
K+
Na+
Has 2+
Ca++
Mg++
Has 1-
Cl-
Has 3-
PO4—
A substance capable of dissolving solute;
Maybe in form of gas or liquid
Solvent
Dissolving medium that is most common
H2O
Substance that is dissolved in a solvent;
Maybe in the form of gas, liquid or solid
Salt and Sugar
Solute
Mixtures of 2 or more particle that are exceedingly small
Solution
Mixture of 2 or more particle that are fairly large
Suspensions
Translucent mixture with solute particles of intermediate size
Albumin-egg white
Colloids
Fluid Mixtures
Solution
Suspensions
Colloids
Mechanisms controlling fluid
Diffusion
Osmosis
Filtration
Dialysis
Movement of solute and water across a semipermeable membrane
Filtration
Use of a machine and a filtration method
DialysisT
The movement of a solute from an area of higher concentration an area of lower concentration within a solvent
Diffusion
There is a uniform distribution of molecules
At equilibrium
Electrolyte Movement
where both mechanism are important in ATP
Passive Transport
Active Transport
Source and transport of Energy
Store and provide energy
ATP
Battery
Source of immediately usable energy for the cell
ATP
ATP facilitates transport through
Sodium-Potassium Pump
What binds to Na-K pump
3 NA and ATP
Outside
Na
Inside
ATP
Osmotic pressure between 2 compartments
Tonicity of fluids
Pressure that needs to be applied to a solution to move through a semi-permeable membrane
Osmotic Pressure
Other name for Osmotic Pressure
Concentration of Solution
The diffusion of a solvent across a selectively permeable membrane
Osmosis
Membrane is permeable to H2o not to?
Albumin
Water movement from L to H concentration
Osmosis
Osmosis measured of fluid?
Osmolality and Osmotic Pressure
Describe the tonicity of the blood plasma/serum
Osmolality
Normal Value of Osmolality
275-300
Higher than normal
Hyperosmolality
Lower than normal
Hypoosmolality
Used to describe all other fluid based on content of Sugars and Salts in solution
Osmolarity
IV fluids
d5%W, Normal Saline (Isotonic)
High salted foods
Hypertonic
Drinks soda, juice sweetened
Hyperosmolar
Plain Water
Hypotonic
Gatorade
Hyperosmolar
H2O excess Results in cellular swelling
Hypotonic Sol
H2O Balance result in no change
Isotonic Sol
H2O deficit results in cellular shrinking
Hypertonic Sol
“Starting’s Law of Fluids”
Hydrostatic Pressure (BP)
Oncotic Pressure (protein)S
Smallest vessel
Capillaries
Pressure of Arterioles
40mmHg
Pressure of Venules
10mmHg
Greater at the arterial end of the capillary than at the venous end
Hydrostatic Pressure
Shifts of plasma fluid to interstitial space/compartment
Edema
Venous Hydrostatic pressure
Elevation
Plasma Oncotic Pressure
Decrease
Interstitial Oncotic Pressure
Elevation
Fluid movement between
Extracellular and Intracellular Fluid
Regulation of water balance
Hypothalamic Regulation
Pituitary Regulation
Adrenal Cortical Regulation
Increased osmolality
Decreased in blood pressure- Increase thirst
An increase in extracellular fluid osmolality stimulates
Thirst and ADH secretion
Increase fluid intake
Increase water reabsorption in the kidneys
A decrease in extracellular osmolality i
Inhibits thirst and decrease ADH secretion
Decrease fluid intake
Decreased water reabsorptions in the kidney
Increased in blood pressure and ANH
Increase Na excretion and increased water loss results in decreased BP
Regulation of Water Balance
Renal Regulation (RAAS)
Cardiac Regulation -(ANH)
Gastrointestinal Regulation (90% intake; 10% metabolism)
Obligatory Water loss
Insensible Water Loss- Lungs GI tract, skin
Average Volume loss/day
600ml
High fluid volume loss
fever>900 ml
Why do men have high water content
More muscle
Which electrolyte is water attracted to
Na
Which hormone is the ultimate regulator of fluids
Aldosterone
What are 2 human conditions that stimulate thirst
Dehydration
Hyperosmolality