FLOW & DEFINITIONS Flashcards
GRANULAR CELLS:
CREATE, STORE, & RELEASE RENIN; CONTRACT WHEN STRETCHED/SYMPATHETIC STIMULI; NEAR ENTRANCE TO RENAL CORPUSCLE; MODIFIED SMOOTH MUSCLE CELLS OF AFFERENT ARTERIOLE.
MACULA DENSA:
SIGNALS GRANULAR CELLS TO RELEASE RENIN THRU PARACRINE STIMULI; DETECTS CHANGES IN NaCl CONCENTRATION OF FLUID IN LUMEN OF DCT; MODIFIED EPITHELIAL CELLS IN WALL OF DCT; ON TUBULE SIDE NEXT TO AFFERENT ARTERIOLE.
What are the cells of the JG apparatus?
Granular cells & Macula densa
The pressure of blood in the glomerular capillaries is called ______ ______ ______.
CAPSULAR HYDROSTATIC PRESSURE (HP)
What is the function of microvilli?
INCREASE SURFACE AREA & REABSORPTION CAPACITY
Follow the path of urine from kidneys to outside the body.
KIDNEYS, URETERS, BLADDER, & URETHRA
Follow the order of tubules leaving the renal corpuscle: PCT to collecting duct.
PCT, NEPHRON LOOP, DCT, COLLECTING TUBULES, COLLECTING DUCTS.
Know the order of different regions of the nephron (the WHOLE nephron, not just the tubules).
RENAL CORPUSCLE, GLOMERULUS, GLOMERULUS CAPSULE, VASCULAR POLE, TUBULAR POLE, RENAL TUBULE, PCT, NEPHRON LOOP (DE/ASCENDING), DCT, COLLECTING TUBULES, COLLECTING DUCTS
What is the function of ADH? When would it be secreted?
INCREASES MIGRATION OF VESICLES CONTAINING AQUAPORINS TO MEMBRANE (ADDS CHANNELS TO INCREASE WATER REABSORPTION); LOW BLOOD PRESSURE, LOW BLOOD VOLUME, & INCREASE IN BLOOD OSMOLARITY
Know the blood flow thru the kidney: Renal artery to interlobular artery.
RENAL ARTERY, SEGMENTAL ARTERY, INTERLOBAR ARTERY, ARCUATE ARTERY.
Blood is filtered by the glomerulus to produce _____. That fluid is then modified along the tubules to produce _____ _____. This fluid finally becomes _____.
FILTRATE, TUBULAR FLUID, URINE
Reabsorption refers to the movement of materials from _____ _____ to _____.
TUBULAR FLUID, BLOOD
Secretion refers to the movement of materials from _____to _____ _____.
BLOOD, TUBULAR FLUID
Know the order of urine flow within the structures in the kidney.
RENAL PAPILLA/PYRAMID, MINOR CALYX, MAJOR CALYX, RENAL PELVIS, URETER, BLADDER.
Where does most tubular reabsorption occur?
PCT