Flavours of cancer Flashcards
Carcinoma
derived from epithelial cells
-prostate, breast, lung, colon
Sarcoma
derived from CT or mesenchymal cells
lymphoma or leukemia
derived from hematopoietic cells
Germ Cell tumor
Drived from pluripotent cells
Blastoma
derived from embryonic tissue
3 majour types of skin cancer
Basal cell carcinoma
squamous cell carcinoma
melanoma
nonmelanoma skin cancer maj risk fac
Defective p53 (tumor suppresor gene)
Basal cell carcinoma
least malignant slow not often metastasize cured by excision 99% time basal cells invade dermis and hypodermis
Squamous cell carcinoma
keratinocytes of stratum spinosum
-most often scalp ear lower lip
grows and rapid metastasize if not removed
prognosis good if radiotherapy or removed
Melanoma
cancer of melanocytes most dangerous rss to chemo highly metastatic wide surgical excision and immunotherapy poor survival rate if more than 4mm thick
Melanoma ABCD
A - assymetric, two sdies of pigmented area dont match
B - border, irregular and has indentations
C - colour, black, brown, tan, red, blue
D - Diameter, larger than 6mm
Hypothermia
Tissue/blood destruction and hemoglobin loss leads hypoxia
Glomerular filtration rate and urinary output reduced and metabolic acidosis
Plasma loss of proteins 4-6 hours post injury results in reduced intravascular colloid pressure causing plasma fluid loss