Flash card assignment
Succ trade name
Anectine
Succ class
Depolarizing NMBA
Succ indications
Medicated facilitated intubation after administration of sedation/analgesic
Succ contras
Hypersensitivity, known or suspected hyperK+, family hx of MH or psuedocholinesterase deficiency, myopathies associated with elevated CK
Succ dose
Adults 1.5mg/kg IV/IO
Peds 1.5 - 2.0 mg/kg IV/IO
Succ additional considerations
Don’t be a dick
*Consider withhold in difficult airway
Takes 60-90 secs for full effect
Acute airway burns not a cause for hyperK+
Roc trade name
Zemuron
Roc class
Non depolarizing NMBA
Roc indications
Post intubation to facilitate airway control and maintain muscle relaxation
Roc contras
Hypersensitivity
Roc dosage
Adult 1mg/kg IV/IO repeated 0.5mg/kg IV/IO PRN
Roc ped dose
Exact fucking same as adult
Vecuronium trade name
Norcuron
Vecuronium class
Non depolarizing NMBA
Vecuronium indications
Post intubation for airway control and maintain muscle relaxation
Vecuronium contras
Hypersensitivity
Vecuronium adult dose
0.1mg/kg IV/IO maintain at 0.01-0.05mg/kg IV/IO Q 20-40
Vecuronium peds
Exact fucking same as adults
Roc additional considerations
Don’t be a dick
Antibiotics (micins) or CCB (dipine) can potentiate effects of roc
Can increase BP, heart rate, induce bronchospasm
NO histamine release
Duration of paralysis 20-40 minutes
Time to onset of paralysis 1-3 minutes
Vecuronium additional considerations
Don’t be a dick
Micins and CCBs can potentiate
No histamine release, cardiovascular effects are minimized
Pancuronium Bromide trade name
Pavulon
Pancuronium Bromide class
Non depolarizing NMBA
Pancuronium Bromide indications
Post tube to facilitate airway control and maintain muscle relaxation
Pancuronium Bromide contas
Hypersensitivty
Pancuronium Bromide adult dose
0.1mg/kg IV/IO maintain at 0.01mg/kg q 20-40 IV/IO
Pancuronium Bromide peds dose
Exact fucking same as adults
Pancuronium Bromide additional considerations
Don’t be a dick
Is the prototype non depol NMBA
NO histamine release, minimal cardiovasc effects
30-45% of drug undergoes hepatic metabolism
Atropine Sulfate trade name
Atropine
Atropine Sulfate Class
Anticholinergic, parasympatholytic
Atropine Sulfate indications
Symptomatic bradycardia, organophosphate poisoning
Atropine Sulfate contras
Hypersensitivity
Atropine Sulfate dose adult for bradycardia
0.5mg IV/IO q3-5 max 3mg
Atropine Sulfate adult dose organophosphate poisoning
2mgIV/IO/IM q5 prn until sludgem reversed
Atropine Sulfate peds for brady
0.02mg/kg IV/IO single max of 0.5
May give q3-5 prn ma of 0.04mg/kg or 1mg
Atropine Sulfate peds organo poisoning
0.05mg/kg q5 prn until DJ BMSLUDGE reversed
Atropine Sulfate additional considerations
Drug of choice in acute symptomatic bradycardia (if immediately reversible causes are not found)
Immediate pacing may be considered over atropine in 2nd degree type II or 3rd degree block
Atropine should not be administered to pts with a hx of heart transplant
Ipratropium Bromide trade name
atrovent
Ipratropium Bromide class
Antichol, parasympatholytic
Ipratropium Bromide indications
bronchospasm, anaphylaxis
Ipratropium Bromide contras
Hypersensitivity
Ipratropium Bromide adult dose
Neb 500mcg repeat prn
MDI w/spacer 10 puffs ONLY if pt has no received 3 doses of nebulized atrovent, repeat q 20 max 30
Ipratropium Bromide pediatric dose
Less than 20kg - 250mcg with ventolin
Greater than 20kg - 500mcg with ventolin nebbed
Ipratropium Bromide additional considerations
Each puff 20mcg
Invert canister multiple times prior to each puff
Depress 3x away prior to
As pt begins to inhale, deliver one puff
Direct pt to continue to inhale slowly then hold breath 5-10 seconds
Allow pt to breath into chamber 5 times
MDI requires 30 seconds between puffs
Alternate single puffs with salbutamol during recharge period
Dopamine trade name
Intropin
Dopamine class
Adrenergic agonist, vasopressor, inotropic, sympathomimetic
Dopamine indications
Shock management, sepsis, pulmonary edema, symptomatic bradycardia,
Beta blocker/ calcium channel blocker OD
Dopamine contras
Pheochromocytomo Tachyarrythmias V fib MAOI within 14 days Allergy to sulphites
Dopamine dose
Adult initial 5mcg/kg/minute titrate to max dose of 20
Dopamine peds
2-20mcg/kg/minute - titrate to effect
Dopa renal dose
Increased renal at 2-5mcg/kg/min
Dopa beta 1 dose
5-10mcg/kg/min
Dopa A1 effects
10-20mcg/kg/min
Dopa additional notes
400mg/250ml saline or D5W = 1600mcg/mL use baxter control-a-flow and a 60 drop set
Dobutamine trade name
Dobutrex
Dobutamine class
Adrenergic agonist, beta 1 agnoist, inotropic, sympathomimetic
Dobutamine indications
Hypotension with symptoms of shock with SBP 70-100 (after fluid)
Hemodynamically significant RV infarct after moderate fluid loading
Dobutamine contras
Hypersensitivity, pheochromocytoma, tachyarryhtmias
Dobutamine dose
Dose 5-20mcg/kg/min adults and peds
Dobutamine notes
ADd 250mg into 250ml (D5 or NS) = 1000mcg/mL
Use with caution if pt has sulfite allergy
Epi trade name
Adrenalin
Epi class
Adrenergic agonist, bronchodilator, vasporessor, sympathomimetic
Epi indications
Symptomatic severe bradycardia with hypotension, not responsive to other therapy
Anaphylaxis refactory
Severe asthma with an allergenic component
Beta blocker/calcium channel blocker OD
Epi contras
Naw
Epi dose
Infusion at 1mcg/min increase by 1mcg/min prn
Titrate to SBP 90 or greater
Additional epi notes
Add 1.5mg epi 1mg/mL to 250mL (NS or D5) concentration of 6mcg/mL
Use 60tts
Norepi trade name
Levophed
Norepi class
Adrenergic agonist, vasopressor, sympathomimetic
Norepi indications
Symptomatic bradycardia
Shock with hypotension after fluid resusication
Cardiogenic shock with refractory hypotension
Norepi contras
Hypovolemia, profound hypoxia, preggo
Norepi contras
Dose 0.1mcg/kg/min IV/IO titrate to max of 1mcg/kg/min
Norepi mixing
16mg into 250mL (D5 or NS) for a conecntration of 64mcg/mL
Isoproterenol trade name
Ispurel
Isoproterenol class
B1 and B2 agonist
Isoproterenol indications
Immediate control AV heart block (after atropine)
Isoproterenol contras
Hypersensitivity, tachycardia caused by dig tox, angina
Isoproterenol contras
2-10mcg/minute IV infusion
Metoprolol trade names
Betaloc, lopressor
Metoprolol class
Beta 1 selective blocker
Metoprolol indications
Symptomatic a-fib, a flutter, with BP > 80mmHg
Metoprolol contras
Hypersensitivity, 2nd or 3r degree AV block, brady under 50, bronchospastic COPD reactive airway disease, severe heart failure
Metoprolol Dose
5mg SIVP q 5 max of 15 Aim for HR of 110
Labetalol trade name
Trandate
Labetalol classification
Alpha 1 B1 and B2 blocker, antihypertensive
Labetalol indications
Hypertensive emergencies
Labetalol contraindications
hypersensitivity Severe and prolonged hypotension HX of obstructive airway disease Overt heart failure 2nd or 3rd degree AV block Cardiogenic shock Severe bradycardia
Adult dose labetalol
Initially 20-80mg IV over 2 minutes
Repeat 40-80mg IV q 2 minutes to max of 300mg as needed
Alternatively may give drug as infusion at 0.5-2mg/minute
Propranolol trade name
Inderal
Propranolol class
B1 and B2 blocker
Propranolol indications
Management of SVT
Propranolol contras
Hypersensitivity Bronchial asthma Sinus brad 2nd or 3rd degree AV block Cardiogenic shock, heart failure (unless secondary to dysrhytmia)
Propranolol dose
Adult
1-3mg IV in 50mL NS do not exceed 1mg/mL
One repeat dose of 3mg may be fiven in 2 minutes
Esmolol trade name
Breviblock
Esmolol class
B1 blocker
Esmolol indications
TX SVT
Esmolol contras
Hypersensitivity
Esmolol dose adult
50-200mcg/kg/min
Phentolamine trade name
Regitine
Phentolamine class
Alpha adrenergic antagonist
Phentolamine indicatins
Antihypertensive for pheochromocytoma
Hypertensive crisis for sympathomimetic amines
TX of dermal necrosis and sloughing of extravasation after IV admin of norepi or dope
Phentolamine contras
Hypersensitivity
Angina
CAD, MI, or HX of MI
Phentolamine dose
Inject 5-10mg in 10mL of NS into affected area
Benztropine Mesylate trade name
Cogentin
Benztropine mesylate class
Anticholinergic, antiparkinsonian
Benztropine mesylate indications
Acute dystonic reactions
Benztropine mesylate contras
Hypersensitivity
Acute angle closure glaucoma
Children under 3
Benztropine mesylate dose
Adult 1-2mg IV/IO/IM
Diazepam trade name
Valium
Diazepam class
Benzodiazepine, skeletal muscle relaxant, amnestic, anticonvulsant, sedative-hypnotic
Diazepam indications
Satus epilepticus/seizures
Skeletal muscle relaxation
Severely anxious or agitated pts
Cocaine OD
Diazepam contras
Hypersensitivity to ANY benzo
Acute narrow angle glaucoma
Diazepam dose
Adult 2.5-5mg IV/IO prn depending on condition
Diazepam ped dose
0.1-0.3mg/kg slow IV or 0.3mg/kg rectally to total of 5mg in child less than 5 years, 10mg >10mg
Lorazepam trade name
Ativan
Lorazepam class
Benzo, skeletal muscle relaxant, amnestic, anticonvulsant, sedative-hypnotic
Lorazepam indications
ETOH withdrawal, acute anxiety
Lorazepam contras
Hypersensitivity to ANY benzo
Acute narrow angle glaucoma
Lorazepam dose
ETOH 1mg SL q 5 max of 4mg
Acute anxiety 1mg SL q5 max of 2mg
Midaz trade name
Versed
Midaz class
Benzo, skeletal muscle relaxant, amnestic, anticonvulsant, sedative-hypnotic
Midaz indications
Active seizure
Combative behavior
Maintenance of paralysis/sedation
Procedural sedation
Midaz contras
Hypersensitivity
Myasthenia gravis
Hypotension (under 100mg)
Midaz dose adult seizure
10mg IM or 5mg SIVP/IO total max 20mg
Midaz dose adult combative behaviour
5mg SIVP or 10mg IV max 20 (same as seizure)
Midaz maintenance of paralysis/sedation
2.5mg SIVP/IO q 10 PRN
Midaz procedural sedation dose
0.05mg/kg SIVP max 2.5mg do not repeat
Midaz ped seizure dose
seizure 0.2mg/kg IM/intranasal max 10mg OR 0.1mg/kg SIVP/IO max 5mg
Midaz peds paralysis/sedation dose
0.05mg/kg SIVP/IO single max 2.5mg
Propfol trade name
Diprivan
Propofol class
Anesthetic
Propofol indications
Conscious sedation
Propofol contras
none apparently
Propofol dose adult
2-2.5mg/kg IV
Usually given in 40mg bolus q 10 seconds until effect achieved
If old or hypovolemic give half dose
Ketamine trade name
Ketalar
Ketamine class
Anesthetic
Ketamine indications
Sedation prior to intubation
Pain management refractory to analgesics
*pushed too fast can cause apnea
Ketamine contras
Hypersensitivity
Significant elevation of BP - relative consideration as this may lead to angina/heart failure or aneurysms
Ketamine dose adult
Sedation 1.5mg/kg SIVP/IO do not repeat
Sedation maintenance 0.5mg/kg SIVP/IO Q10 PRN
Pain management 0.2mg/kg SIVP/IO
Ketamine peds dose
exact fucking same as adult