Fish Medicine Flashcards

1
Q

‘Pet’ fish temperate freshwater - Goldfish basic requirements (Teleosts)

A
  • 30 L water per fish
  • 1 ft^2 of air surface per fish, can be reduced by aeration (pump pushing air through water, will inc SA + reduce air at tank to maintain oxygenation)
  • Maintain 18 - 20 C, warmish room temp
  • Cope in open-air pond year-round
  • Ponds preferable to tanks if deep enough to avoid freezing/shade available in summer
  • Feed on crustaceans + plants or pelleted food (flakes)
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2
Q

Koi karp

A
  • Large ponds 1.5 m depth
  • Filter w/ biological + physical filtration to accommodate their size + metabolism
  • Multiple chambers in filter - filter out lumps of organic material -> sand type, takes out smaller particles -> biological filter - may be spoken w/ bacteria that break down protein by-products in water + remove, water flows back = relatively clean
  • Aeration - waterfalls for larger systems
  • Commercial diets - vit C, carotenoids to maintain bright colouration
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3
Q

Common issues of carp

A
  • Water quality failings, problems w/ protein breakdowns - inc NH3, nitrates or nitrites - should be removed by water changes/used by aquatic plants
  • Any organic material in water produces NH3 + NH4+
  • NH3 more toxic - causes damage to surface of fish + diffuses across gills
  • Need idea of proportion of NH3 : NH4+
  • Mod levels but have alkaline pH/high temps, get shift of NH4+ -> NH3, will higher NH3 than results suggest
  • NH3/NH4+ oxidised by bacteria mostly in filtration system -> NO2- (nitrite) -> oxidised further to nitrate (NO3^2-), dec toxicity, tend to be sequestered in water + doesn’t go far, used by some aquatic plants + take it out the water
  • Can have systems w/ de-nitrifying towers - remove nitrites
  • Small amount removed as N2 gas
  • To remove majority of nitrates, will have to do water changes
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4
Q

Causes of spikes in NH3/nitrates/nitrites

A
  • 1). Failure to prepare + mature a tank + filter - bacteria need to be implanted into system + build-up its numbers, prepare tank
  • Filter before introduce fish using filtration material from another tank to populate the filter or commercial liquid populations to put on sponges -> run tank w/ organic material e.g. fish food and allow to stabilise for few w
  • 2). Overstocking - can be gradual as fish grow/breed, may be too small filter
  • When sudden inc in no. fish by new group + don’t allow filter to adapt
  • 3). Failure of filter - stop water circulating, place AB -> kill all bacteria
  • 4), Overload or organic material -> overfeeding, algal or plant bloom, dead fish
  • Inc feed
  • Algae die -> inc release of organic matter
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5
Q

Consequences of spikes in NH3 (first stage)

A
  • 1). Irritation of skin - discomfort, ulceration, inc risk of skin infection
  • Become more active + twisting in water/rubbing against side of tank/pond
  • Ammonia burns
  • Abrasions - rubbing against things
  • Skin infection - barrier of skin damaged + opportunistic bacteria can take advantage + cause ulceration + infection
  • 2). Gill epithelial hyperplasia - 2y effects on oxygenation -> resp signs, reduced osmosis + NH3 excretion
  • Thickened gills - don’t have effective diffusion - less O2 pass over -> hypoxia
  • More vulnerable to hypoxic stress
  • Resp signs
  • Dec excretion of toxins
  • 3). General debilitation due to chronic stress
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6
Q

Consequences of spikes in nitrites (NO2-)

A
  • Inc nitrite absorption
  • Hb oxidised to methaemoglobin - doesn’t carry Hb as efficiently
  • Hypoxia due to reduction in O2 transport
  • Pale tan mucosa + gills
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7
Q

Consequences of spikes in nitrates (NO2^3-)

A
  • Rarely clinical in itself - not particularly toxic
  • May affect eggs + fry - juveniles affected, may affect fertility + development of fry
  • Facilitates algal + plant bloom, only produce O2 during the day - 2y drop in oxygenation - use up O2 overnight -> O2 crash = sudden die-off -> sudden release of organic material
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8
Q

Water quality management

A
  • Water changes - 30 - 50% of tank pond vol, don’t replace w/ normal tap water, chloramines will wipe out filter bacteria + toxic to fish, need sample of pre-prepared water, allowed to age + allows chlorine gas to diffuse out or Tx water w/ commercial products to remove chlorine + chloramine
  • Add zeolite to bind NH3 + immediately removes from water, but cannot leave in place or NH3 released bak out into water, take out + place in salt water + reuse = temp sink for NH3
  • Reduce organic load - remove algae + plants overgrowth, reduce feeding - can just stop feeding for few days
  • Remove debris - siphoned out but be aware of dec water quality
  • Improve oxygenation - aerate water, cool or shade water if hot weather - will hold more O2 at cooler temps - ice bottles or adding colder water
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9
Q

Longer term water quality management

A
  • Identify + manage cause
  • If fish died = remove, simple matter
  • Allow filter maturation - re-populate
  • Inc filter capacity
  • Reduce stocking of plants or fish
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10
Q

Low O2 saturation

A
  • 1). High biomatter load - algae, fish decomposing vegetation - plants overnight when CO2 production continues + no O2 produced
  • 2). High temps - O2 saturation dec w/ inc temp
  • Severe issues
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11
Q

Low O2 saturation - CS + Dx

A
  • 1). Die off - early morning when O2 lowest
  • 2). Fish gathering at point of aeration - trying to suck in air at surface
  • Failure of normal diffusion - gill damage, or not enough O2
  • 3). Signs of chronic stress - ulcerative skin disease, mortality of already compromised fish
  • Dx - measure O2 saturation at sunrise
  • Lower mortality at milder stages - those already compromised e.g. tumours are the ones that die first but still down to O2
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12
Q

Low O2 saturation - managment

A
  • Remove biomass - stable oxygenation throughout day + night
  • Inc aeration e.g. hose at height, fountains, waterfalls, commercial - depends on size of the enclosure, aeration stones in small tank
  • Dec stocking density - relocate permanently/temporary removal until dealt w/ 1y issues
  • Provide shade/cool water
  • Monitor nitrogen processing - NH3 + nitrites also inc due to common factors
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13
Q

Ulcerative skin disease - parasitic

A
  • Common in koi
  • Protozoa - Ichtypthirius multifillis (Ich) - small white spots + irritation of fish - rubbing + showing irregular movements
  • Gyrodactylus skin flukes
  • Dactylogyrus gill flukes
  • Argulus lice
  • Lernea anchor worm -> focal irritation
  • Then can get 2y bacterial infection due to injury to skin
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14
Q

Ulcerative skin disease - bacterial (1y infection)

A
  • Aeromonas spp most common - diffuse reddening + 2 y ulceration when skin sloughs off
  • Range of environmental bacteria can be opportunistic invaders - Pseudomonas - when got skin surface damage
  • Primary bacterial infection rare - commonly 2y: trauma, damage to skin barrier e.g. high NH3
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15
Q

Skin disease - viral

A
  • Rarely ulcerative
  • Cyrpinid herpes
  • Can be ulcerative but typically presents w/ raised plaques
  • Not great deal to Tx - will remain infected
  • Will see viral flares - cold, dec immune system but low mortality
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16
Q

Skin disease - fungal

A
  • Typically 2y
  • May be ulcerative
  • Can present as ‘fluffy’ growths
  • Fungi within water colonise
  • White or greeny-brown colour
17
Q

Approach to ulcerative skin disease - investigation

A
  • Assess pond/tank side where possible - samples brought into the clinic will deteriorate over time, diff temps + conditions
  • Test water parameters - NH3, nitrites, O2
  • Assess individual fish for gross lesions + macroscopic parasites
  • Severity + location of lesions
  • Normal fish - any minor changes?
  • Collect swab samples for culture
  • Collect scrapes for cytology/parasitology - examine immediately if possible
18
Q

Ulcerative skin disease - Tx

A
  • Medication for specific cause - in main tank/pond or in isolation tank
  • Consider adding low-dose salt to reduce osmotic stress - 1 - 2 g/L, can improve overall fish health
  • Manage water quality carefully
  • Reduce stressors
19
Q

Medication admin of fish medicine

A
  • Orally - compound into pelleted or gel food (set in ice cube trays - indv Tx) - oxytetracycline for koi + pond fish
  • Can create own mix
  • Injections - epaxial muscles either side of dorsal fin, hard to restrain (stressful)
  • In water - dissolve/dilute, bypass filtration system - remove bacteria/take fish out until cleared out bacteria, powder/liquid directly y in water then return to normal pond
  • Short term dips of higher conc
  • Temp affects dosing requirements + freq
20
Q

Swim bladder disorders

A
  • Goldfish
  • Altered buoyancy - suggestive, but can be due to GI disease (distension), neoplasia, granulomas (TB) or ascites (renal neoplasia)
  • Stuck at top/bottom of tank, unable to feed well, bump into walls, abrasions around eyes
  • 2y concerns - inability to feed, abrasions
  • Infection/anatomical disruption alters swim bladder filling
  • Dx - radiographs - highlight swim bladder alterations in position, size or shape
    (Elasmobranchs + some bottom-dwelling teleosts e.g. flounders + some pelagic teleosts e.g. tuna lack a swim bladder)
  • Physoclistous species - marine teleosts, cichlids, bass + sunfish - gases diffuse into swim bladder from rete mirabile - bloodstream ‘gas glands’
  • Physostomous species (koi + goldfish, catfish, salmon + trout, tetras) - pneumatic duct connects oesophagus + swim bladder, bacteria, fluid, FB or food can enter swim bladder = more swimbladder issues; koi have rete mirabile as well as duct
21
Q

Swim bladder disorder - Dx

A
  • Radio/US to check for mass or fluid displacing the swim bladder - done consciously, cope for short periods w/o water, put in dish where cannot jump out in lateral
  • Aspirate for culture + cytology -> AB
  • US - when fluid/water gets in the way
  • V fibrous tissue - hard to interpret mass unless well-defined
  • Can instil sterile saline + aspirate back if appears to not have much fluid in swim bladder
22
Q

Swim bladder disorder - Tx

A

Based on findings
- Systemic antimicrobials - Oxytetracycline to start off before get C&S results back
- AB instil directly into swim bladder but can cause irritation due to presevatives
- Feed larger food items to trigger opening of pneumatic duct to allow equalisation of pressure between swim bladder + oesophagus
- Remove hazards from, if got over distension of swim bladder, feeding goldfish peas to normalise swim bladder
- Adapt environment - remove any decor that they may collide w/ + injury themselves
- Guarded Px - most present well-on in the disease

23
Q

Notifiable disease

A
  • Spring viraemia of carp
  • Koi herpes virus
  • Contact APHA for advice + testing if high mortality, weird-looking skin/gills
24
Q

Spring viraemia of carp

A
  • Petechial H+ of skin, gills + eyes
  • Exophthalmos - protrusion of eyes
  • Pallor - of mm
  • High mortality
25
Q

Koi herpes virus

A
  • Anorexia, lethargy
  • Gill necrosis
  • Skin pale patches
  • Erratic swimming
  • High mortality
26
Q

Tropical freshwater - common conditions

A
  • Water quality issues - if have breakdown of aeration system can lead to O2 depletion but less common as less temp variation + less vegetation overgrowth
  • Fin rot (similar pathology to ulcerative skin disease)
  • Conspecific and intraspecific trauma - deplete numbers when grow in size
  • Mycobacterium marinum - zoonotic, occasional issues
  • Lymphocystis
  • White spot (Ich)
  • Fungal skin disease
  • Velvet (Piscinoodinium)
  • Hole in the head (Hexamita)
27
Q

White sport (Ich)

A
  • Protozoa - Ichthyophthirius multifilliis
  • < 1 mm, appear as fine white dots over skin and cause
  • 2y dermatitis
  • Inc mucus, ulceration
  • Gill damage pos -> more sig signs when damages diffusion
28
Q

White spot (Ich) - Tx

A
  • Over-the-counter copper-based water treatment
  • UV filtration of water will reduce protozoal replication + breaks lifecycle
  • Raise temps to 30 C over 48 - 72 h to reduce protozoal replication + kill them off a bit faster
  • 1g/L salt added into water -> dec stress
29
Q

Mycobacterium marinum (TB)

A
  • All fish species, causes
  • Ulcerative skin disease, less common
  • Visceral granulomatous form, most cases, only find out PME - lethargy, anorexia, loss of condition, coelomic distension, but lose of muscle + overall condition
  • Dx - identification on biopsy of skin lesions of histopath of granulomas at PME
  • Slower progression
  • Impossible to erradicate from shoal
  • Depopulate, disinfect, dry out tank
  • Quarantine new fish for 2 m
30
Q

Hole in the head

A
  • Affects cichlidae (cichlids, discus + Oscars)
  • Presents as shallow ulcers on head + sides
  • Due to Spironucleus flagellated protozoa (catfish - Edwrdsiella ictaluri -> head ulcers)
  • Mortality low but may be part of chronic stress or co-morbidity w/ higher mortality, presents when other issues going on
  • Metronidazole given in food or in water (less effective) but recurrence occasionally seen, repeat Tx
  • In catfish - Edwardsiell ictaluri causes head ulcers = similar presentation but Tx w/ AB
31
Q

Marine tropical - common diseases

A
  • Water quality issues
  • Cryptocaryon (similar to Ich protozoal)
  • Marine velvet (Amyloodinium)
  • Lymphocystis
32
Q

Lymphocystis (Irdovirus)

A
  • Marine angelfish, butterfly fish + clownfish; cichlids (brackish/freshwater)
  • Viral infection causes fibroblasts to balloon in size
  • Hypertrophied cells of 1 mm diameter are visible as white dots
  • Disfiguring but low mortality
  • Lesions recur spontaneously but relapse is pos at times of stress
  • Tx/management - accept endemic lymphocystitis or cull affected animals