first test #1 Flashcards

1
Q

3 components of the glomerular capillary wall from inside out

A
  1. endothelial cells (with fenestra)
  2. Glomular basement membrane
  3. Visceral epithelial cells
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2
Q

glucose renal threshold is 160-180 mg/dl

A

maximum range of glaucoma reabsorption in the renal tubule

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3
Q

aldsosterone is for _____ reabsorption and is released by the the ______ _____

A

sodium, zona glomerulosa (adrenal cortex)

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4
Q

releases the trigger for angiotensin II

A

aldosterone

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5
Q

order of cellular cast degradation

A

cellular >granular>waxy

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6
Q

indicates cholecystitis

A

murphey’s sign

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7
Q

green brown urine usually indicates

A

cholecystits (positive murphy’s sign)

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8
Q

urine dark with yellow foam

A

Icterus/jaundice

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9
Q

presence of bilirubin in urine

A

Liver or gallbladder disease

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10
Q

elevated level of conjugated serum bilirubin implies

A

liver disease or cholestatic disease

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11
Q

Direct bilirubin is soluble in water (conjugated)

A

true

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12
Q

Bilirubin+albumin is unconjugated

A

non water soluble

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13
Q

bilirubin comes from the breakdown of

A

hemoglobin

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14
Q

what increases urobilnogen

A

hemolytic anemia

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15
Q

ketones + suger =

A

diabetes mellitus

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16
Q

down regulation of receptors is usually an issue for

A

diabetes mellitus

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17
Q

______ are made by the liver for ____ metabolism

A

ketones, fat

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18
Q

Renin is release by the______ of the kidney is response to volume _____

A

juxtaglomerular, depletion

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19
Q

what is a precursor to angiotensinogen

20
Q

sudden onset of severe pain originating at the flank and radiating inferiorly and anteriorly

A

renal colic

21
Q

Ca Oxalate and amophous crystals are found in ___ PH ruine and in ______ solute concentration

A

low (below 7), high

22
Q

renal colic what test should be positive

A

murphy’s punch

23
Q

Ca Oxalate crystals can indicate

A

Kidney stones

24
Q

drinking alcohol puts one at greater risk for

A

kidney stones

25
ADH works at the _______ of the kidney
Cortical collecting tubule and the collecting duct
26
signs of pyelonephritis (infection)
increase wbcs, painful urination, no sexual activity
27
Glomerulonephritis
inflammation of kidney not associated with infection
28
Most likely bacteria of UTI
e.coli
29
what ph of urine is optimal for e.coli
7.24 (7+ to survive)
30
high specific gravity with, cholesterol crystals, fatty/ waxy casts, with lots of edema and ascites
nephrotic syndrome
31
_______ is commonly associated with nephrotic syndrome in adults
glomerulonephritis
32
cannot metabolize branch chain amino acids (leucine, isoleucine, valine)
maple syrup urine disease
33
alport syndrome
glomerulonephritis, manifested by nephritic syndrome
34
spenomegaly, hepatomegaly are associated with
alport syndrome
35
ADH is produced in the ______ and released by _____
hypothalamus, posterior pituitary
36
Diabetes insipidous
polyuria, insufficient ADH, low specific gravity due to frequency of urination
37
most common cause of metabolic alkalosis
vomiting (loss of H+)
38
rbc casts, mild to moderate proteinurea, and no pitting edema...
nephritic syndrome
39
fatty casts 3.4 or more grams of protein and pitting edema
nephrotic syndrome
40
ADH is made in the ______ and released from the _____
hypothalamus, post. pituitary
41
Usually found with UTIs
triple phosphate
42
GMN signs
proetinuria, hematuria, darker urine, edema, hypertension, oliguria
43
uncontrolled DM, what is the immediate threat?
GMN
44
ketones with absence of glucose but not dieting ____ must be considered in the diff diagnosis
cancer
45
elevated HCG levels in 24 hour urine specimen may indicate what?
pregnancy