First Line Drugs Flashcards
Adrenaline dosages
1mg (1:10,000) IV/IO
2 mg ETT
Adrenaline paediatrics dosages
10mcg/kg IV or IO
100mcg/kg ETT
Adrenaline administration: shockable
After 2nd shock
Then every second cycle (4 mins)
Adrenaline administration: non shockable
During initial CPR
Then after every 2nd cycle (4 mins)
Indications for adrenaline
Asystole
PEA
Bronchospasm
Anaphylaxis
pVT/VF not responding to initial defib
Adverse effects of adrenaline
Tachycardia
Severe hypertension
Tachyarrhythmia
Hyperglycaemia
Tissue necrosis with extravasation
Action of adrenaline
Peripheral Vasoconstriction
Increase myocardial contractility and heart rate
Relaxation of bronchial smooth muscle
Peripheral vasoconstriction conserves circulating volume to myocardium and brain
Action of amiodarone
Class 3 antiarrhymic
Blocks potassium channels and slows AV conduction
Amiodarone indications
Failure of defib and adrenaline to revert VF/ pVT
Prophylaxis recurrent VF/VT
Conscious VT, AF, Atrial flutter, SVT
Amiodarone dosages
Initial 300mg
Consider additonal 150mg
Amiodarone paediatric dosages
5mg/kg to max 300mg
Administration of amiodarone and timing in cycle
300mg in 20ml 5% glucose IV/IO bolus over 2 mins
Should be administered between 3rd and 4th shock
Consider additional dose 150mg after 5th shock
Administration of amiodarone in conscious VT, AF, SVT
5mg/kg in 100ml 5% glucose IV over 20-30 mins
Paediatric administration of amiodarone (time)
IV/IO bolus over 2 minutes
Contraindications of amiodarone
Sinus bradycardia
Sinoatrial heart block
