First Aid for the Psychiatry Clerkship - "Neurocognitive Disorders" Flashcards

1
Q

Put simply, neurocognitive disorders are defined by ____________________.

A

a decline in cognitive function from baseline

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2
Q

List the five categories of delirium that are in the DSM-5.

A
■ Substance intoxication delirium
■ Substance withdrawal delirium
■ Medication-induced delirium
■ Delirium due to another medical condition
■ Delirium due to multiple etiologies
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3
Q

You are called to assess delirium in an elderly patient in a nursing home. You suspect a medication might have caused it. What is First Aid’s mnemonic for assessing drug-induced delirium?

A
VALEUMS:
■ Vital signs
■ Alertness Level
■ Eyes (pupil size and position)
■ Urine (bladder distension or
incontinence)
■ Mucous membranes (moisture)
■ Skin (temperature and moisture)
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4
Q

The most common type of delirium is ___________________.

A

mixed type, in which the person fluctuates between hyperactivity and hypoactivity

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5
Q

____________ delirium is more likely to go undetected.

A

Hypoactive

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6
Q

What are the DSM-5 criteria for delirium?

A
  • Alterations in attention and awareness
  • Impairment in at least one additional cognitive domain (like memory)
  • Not due to another neurocognitive disorder
  • Evidence that suggests the impairment is due to a medication, abnormal lab value, or medical stressor
  • Acute development
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7
Q

What’s the difference between being lethargic and being stuporous?

A

Lethargy means you are drowsy but can be aroused, while stupor means you are drowsy and cannot be aroused.

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8
Q

True or false: benzodiazepines can help treat agitated patients with delirium.

A

False. Benzodiazepines generally worsen delirium. The only exception is in delirium due to alcohol withdrawal.

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9
Q

What five categories of testing does the Mini Mental State Exam test?

A

L ROAR

  • Language (naming objects, repeating a short sentence, writing a sentence, reading a sentence)
  • Recall (three objects after five minutes)
  • Orientation
  • Attention (serial 7’s)
  • Registration (three objects immediately)
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10
Q

What is the Mini-Cog test?

A

The Mini-Cog test is a three-item recall and a clock drawing. A positive screen is an abnormal drawing and no items recalled at three minutes.

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11
Q

The three primary domains affected in Alzheimer’s dementia are _______________.

A

language, learning, and memory

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12
Q

Cholinesterase inhibitors are effective at ____________________ Alzheimer’s disease.

A

delaying the deterioration

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13
Q

NMDA antagonists like _____________ have been shown to provide a modest benefit to those with Alzheimer’s.

A

memantine

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14
Q

_____________ should not be given to those with Alzheimer’s for extended periods because they are associated with increased mortality.

A

Antipsychotics

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15
Q

Any treatment plan for Alzheimer’s should include ___________ support.

A

caregiver

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16
Q

______________ is the second most common cause of dementia.

A

Vascular dementia

17
Q

What is the classic progression of vascular dementia?

A

Sudden onset with gradual partial improvement

18
Q

What are signs and symptoms of Lewy body dementia?

A
  • Hallucinations (“haLEWcinations”)
  • Extrapyramidal symptoms
  • Waxing and waning of cognition
  • REM sleep disorder
  • Pronounced sensitivity to antipsychotics
19
Q

How should Lewy body dementia be treated?

A
  • Low-dose quetiapine or clozapine for psychotic symptoms
  • Levodopa/carbidopa for Parkinsonism
  • Cholinesterase inhibitors for dementia

Monitor closely for NMS!

20
Q

Oral exploration of inanimate objects is a feature of ________________ dementia.

A

frontotemporal

21
Q

What class of medications has been shown to reduce disinhibition in frontotemporal dementia?

A

SSRIs

22
Q

What is the Huntington’s triad?

A
  • Psychiatric: mood changes
  • Cognitive: dementia
  • Motor: chorea and bradykinesia
23
Q

Creutzfeldt-Jakob disease usually presents with ______________.

A

rapid cognitive decline