FINALS - Genetics and Forensics Flashcards
early development of ISH uses ___ as target labels and was changed to ___
radiolabeled probes; fluorescence probes
TAGGING technique where a probe is added into the sample or reagent and DNA polymerase I is used to replace some nucleotides of DNA sequences
nick translation
there is NO CELL CULTURE required, thus the diagnosis is much rapid
interphase FISH
on the SINGLE chromosome, there are lots of UNIQUE DNA associated with it
WCP
there is a system or program installed wherein the main profile is already uploaded there and it is just compared with the said sample
MFISH
you will be able to observe MULTIPLE CHROMOSOMAL ABERRATIONS
SKY
a telomere probe is used to recognize SIX base repeats and is used to confirm the presence and absence of TELOMERIC regions
ALL - Telomere FISH
SIMPLE COMPARE the DNA content of a differentially labeled normal and abnormal cell population
comparative genomic hybridization
done so as to detect congenital inherited or genetic diseases or disorders
prenatal analysis/diagnosis
common specimen in forensics
hair
MOST common specimen in forensics
fingerprints
considered as the BEST SAMPLE in forensics
blood
one of the specimens having a SMALL CONCENTRATION of DNA
urine
short sequences of bases that repeats many times
short tandem repeats (STR)
acts as FILLERS or SPACERS between the coding portions of the chromosome
STR
