Finals 2022 : Protein Synthesis (and Gene Expression) Flashcards

1
Q

Adenine Definition

A

A compound which is one of the four constituent bases of nucleic acids.

Paired with thymine in double-stranded DNA.
Paired with Uracil in RNA.

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2
Q

Amino Acid Definition

A

Special organic molecule used by living organisms to make proteins. (carbon, hydrogen, oxygen, nitrogen). They are formed from codons.

  • Bonded together into long chains which fold into a three-dimensional shape.
  • Every amino acid is made up of a foundational molecule, which is the same for all amino acids.
  • There are 20 different “R” groups, resulting in 20 different amino acids.
  • Amino acids are joined in long chains called polypeptides before they fold into their complex, 3-dimensional, functional shape.
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3
Q

Anticodon Definition

A

Three nucleotides that form a unit of genetic code in tRNA molecule, corresponding to a complementary codon in mRNA.

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4
Q

Chromosome Definition

A

Chromosomes are highly organized and contain all the genetic information necessary to code for proteins. They are condensed, organized packages of DNA.

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5
Q

Codon Definition

A

3 consecutive nucleotides that code for a specific amino acid or signals the start or end of gene translation.

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6
Q

Cytosine Definition

A

A compound which is one of the four constituent bases of nucleic acids.

Paired with Guanine in double-stranded DNA.

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7
Q

Deletion Point Mutation Definition

A

A type of mutation involving the loss of genetic material.

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8
Q

Deoxyribose Definition

A

Sugar found in DNA.

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9
Q

DNA Definition

A

Deoxyribonucleic acid

Stores all of the genetic information inside the cell.

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10
Q

Feedback Loop Definition

A

Where the output of a system amplifies the system (positive feedback) or inhibits the system (negative feedback).

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11
Q

Frameshift Mutation Definition

A

When nucleotides are inserted into or deleted from the DNA and cause a “shift” in the reading of mRNA codons.

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12
Q

Gene Definition

A

A sequence of DNA that contains the instructions to build a specific protein.

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13
Q

Gene Expression Definition

A

The activity of genes in a cell. In each cell, only some of the genes are active or expressed.

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14
Q

Guanine Definition

A

A compound which is one of the four constituent bases of nucleic acids.

Paired with Cytosine in double-stranded DNA.

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15
Q

Insertion Point Mutation Definition

A

When an extra base pair is added to a sequence of bases.

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16
Q

mRNA Definition

A

During the Transcription, the information contained in DNA is converted into a messenger molecule (mRNA).

17
Q

Nucleus Definition

A

The membrane-enclosed organelle within a cell that contains the chromosomes.

18
Q

Nucleotide Definition

A

The building blocks of the nucleic acids RNA and DNA.

A nucleotide is composed of a nucleobase (nitrogenous base), a five-carbon sugar (either ribose or 2-deoxyribose), and one phosphate group.

19
Q

Point Mutation Definition

A

A mutation affecting only one or very few nucleotides in a gene sequence.

20
Q

Ribose Definition

A

Sugar found in RNA.

21
Q

Ribosome Definition

A

An intercellular structure made of both RNA and protein, and it is the site of protein synthesis in the cell.

22
Q

RNA Polymerase Definition

A

A multi-unit enzyme that synthesizes RNA molecules from a template of DNA through a process called transcription.

23
Q

Protein Definition

A

One of the most common organic macromolecules made up of chains of monomers called amino acids.
(carbon, hydrogen, oxygen)

  • Made of 20 amino acids
  • Theoretically, an infinite number of proteins can be made based on different combinations of all 20 amino acids.
  • Weak bonds help the protein maintain its shape.
  • Proteins are involved in nearly every function of your body.
    Ex. Muscles, skin, hair

Cells contain about 10,000 different proteins with different jobs.

  • Provide structural support
  • Transport substances inside the cell and between cells
  • Communicate signals within the cell and between cells
  • Speed up chemical reactions
  • Control cell growth.
24
Q

Stimulus Definition

A

Anything that produces a response in an organism or in a cell or tissue of an organism. Such stimuli can be internal or external.

25
Substitution Point Mutation Definition
A type of mutation in which one nucleotide is replaced by a different nucleotide.
26
Thymine Definition
A compound which is one of the four constituent bases of nucleic acids. Paired with Adenine in double-stranded DNA. Replaced with Uracil in RNA.
27
Transcription Definition
The first phase of protein synthesis. The information contained in DNA is converted into a messenger molecule called messenger RNA (mRNA). - Happens in the nucleus.
28
Transcription Factors Definition
Molecule that controls the activity of a gene by determining whether the gene's DNA (deoxyribonucleic acid) is transcribed into RNA (ribonucleic acid).
29
Translation Definition
The second phase of protein synthesis. In this phase, the code in the mRNA molecule is translated by transfer RNA (tRNA), which carries amino acid monomers used to build a protein molecule. - Happens on ribosomes in the cytoplasm of the cell.
30
tRNA Definition
Small RNA molecule that plays a key role in protein synthesis. Transfer RNA serves as a link (or adaptor) between the messenger RNA (mRNA) molecule and the growing chain of amino acids that make up a protein.
31
Uracil Definition
One of the constituent bases of nucleic acids. Compound. Replaces Thymine in RNA. Only present in RNA.
32
List the three types of RNA
mRNA tRNA rRNA
33
Describe three main differences between RNA and DNA.
1. Sugar in RNA is ribose instead of deoxyribose 2. RNA is generally single-stranded, not double-stranded 3. RNA contains uracil in place of thymine.