Finals 2022 : Protein Synthesis (and Gene Expression) Flashcards

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1
Q

Adenine Definition

A

A compound which is one of the four constituent bases of nucleic acids.

Paired with thymine in double-stranded DNA.
Paired with Uracil in RNA.

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2
Q

Amino Acid Definition

A

Special organic molecule used by living organisms to make proteins. (carbon, hydrogen, oxygen, nitrogen). They are formed from codons.

  • Bonded together into long chains which fold into a three-dimensional shape.
  • Every amino acid is made up of a foundational molecule, which is the same for all amino acids.
  • There are 20 different “R” groups, resulting in 20 different amino acids.
  • Amino acids are joined in long chains called polypeptides before they fold into their complex, 3-dimensional, functional shape.
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3
Q

Anticodon Definition

A

Three nucleotides that form a unit of genetic code in tRNA molecule, corresponding to a complementary codon in mRNA.

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4
Q

Chromosome Definition

A

Chromosomes are highly organized and contain all the genetic information necessary to code for proteins. They are condensed, organized packages of DNA.

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5
Q

Codon Definition

A

3 consecutive nucleotides that code for a specific amino acid or signals the start or end of gene translation.

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6
Q

Cytosine Definition

A

A compound which is one of the four constituent bases of nucleic acids.

Paired with Guanine in double-stranded DNA.

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7
Q

Deletion Point Mutation Definition

A

A type of mutation involving the loss of genetic material.

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8
Q

Deoxyribose Definition

A

Sugar found in DNA.

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9
Q

DNA Definition

A

Deoxyribonucleic acid

Stores all of the genetic information inside the cell.

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10
Q

Feedback Loop Definition

A

Where the output of a system amplifies the system (positive feedback) or inhibits the system (negative feedback).

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11
Q

Frameshift Mutation Definition

A

When nucleotides are inserted into or deleted from the DNA and cause a “shift” in the reading of mRNA codons.

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12
Q

Gene Definition

A

A sequence of DNA that contains the instructions to build a specific protein.

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13
Q

Gene Expression Definition

A

The activity of genes in a cell. In each cell, only some of the genes are active or expressed.

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14
Q

Guanine Definition

A

A compound which is one of the four constituent bases of nucleic acids.

Paired with Cytosine in double-stranded DNA.

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15
Q

Insertion Point Mutation Definition

A

When an extra base pair is added to a sequence of bases.

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16
Q

mRNA Definition

A

During the Transcription, the information contained in DNA is converted into a messenger molecule (mRNA).

17
Q

Nucleus Definition

A

The membrane-enclosed organelle within a cell that contains the chromosomes.

18
Q

Nucleotide Definition

A

The building blocks of the nucleic acids RNA and DNA.

A nucleotide is composed of a nucleobase (nitrogenous base), a five-carbon sugar (either ribose or 2-deoxyribose), and one phosphate group.

19
Q

Point Mutation Definition

A

A mutation affecting only one or very few nucleotides in a gene sequence.

20
Q

Ribose Definition

A

Sugar found in RNA.

21
Q

Ribosome Definition

A

An intercellular structure made of both RNA and protein, and it is the site of protein synthesis in the cell.

22
Q

RNA Polymerase Definition

A

A multi-unit enzyme that synthesizes RNA molecules from a template of DNA through a process called transcription.

23
Q

Protein Definition

A

One of the most common organic macromolecules made up of chains of monomers called amino acids.
(carbon, hydrogen, oxygen)

  • Made of 20 amino acids
  • Theoretically, an infinite number of proteins can be made based on different combinations of all 20 amino acids.
  • Weak bonds help the protein maintain its shape.
  • Proteins are involved in nearly every function of your body.
    Ex. Muscles, skin, hair

Cells contain about 10,000 different proteins with different jobs.

  • Provide structural support
  • Transport substances inside the cell and between cells
  • Communicate signals within the cell and between cells
  • Speed up chemical reactions
  • Control cell growth.
24
Q

Stimulus Definition

A

Anything that produces a response in an organism or in a cell or tissue of an organism. Such stimuli can be internal or external.

25
Q

Substitution Point Mutation Definition

A

A type of mutation in which one nucleotide is replaced by a different nucleotide.

26
Q

Thymine Definition

A

A compound which is one of the four constituent bases of nucleic acids.

Paired with Adenine in double-stranded DNA.
Replaced with Uracil in RNA.

27
Q

Transcription Definition

A

The first phase of protein synthesis. The information contained in DNA is converted into a messenger molecule called messenger RNA (mRNA).

  • Happens in the nucleus.
28
Q

Transcription Factors Definition

A

Molecule that controls the activity of a gene by determining whether the gene’s DNA (deoxyribonucleic acid) is transcribed into RNA (ribonucleic acid).

29
Q

Translation Definition

A

The second phase of protein synthesis. In this phase, the code in the mRNA molecule is translated by transfer RNA (tRNA), which carries amino acid monomers used to build a protein molecule.

  • Happens on ribosomes in the cytoplasm of the cell.
30
Q

tRNA Definition

A

Small RNA molecule that plays a key role in protein synthesis. Transfer RNA serves as a link (or adaptor) between the messenger RNA (mRNA) molecule and the growing chain of amino acids that make up a protein.

31
Q

Uracil Definition

A

One of the constituent bases of nucleic acids. Compound.

Replaces Thymine in RNA. Only present in RNA.

32
Q

List the three types of RNA

A

mRNA
tRNA
rRNA

33
Q

Describe three main differences between RNA and DNA.

A
  1. Sugar in RNA is ribose instead of deoxyribose
  2. RNA is generally single-stranded, not double-stranded
  3. RNA contains uracil in place of thymine.