Final-Renal&Synovial Flashcards

1
Q

most imp test of renal fxn

A

GFR

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2
Q

chemstrip is NOT sensitive enough for?

A

microalbuminuria

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3
Q

tea colored urine

A

post strep glomerulonephritis

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4
Q

minimal change dz nothing on ? only see damage to epithelial foot processes on ?

A

light microscopy

electron microscopy

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5
Q

goodpasture syndrome associated with?

A

pulm hemorrhage

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6
Q

RPGN- causes?

A

good pasteur, SLE, ANCA gene

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7
Q

RPGN- serology?

A

anti glomerular basement membrane Ab, dsDNA

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8
Q

sx include fever, chills, CVA tenderness

A

pyelonephritis

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9
Q

creatinine clearance requires

A

24h urine collection

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10
Q

nl GFR?

A

90-120

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11
Q

microalbumin checked for via ? OR ?

A

albumin/creatinine ratio, specimen: random urine sample during day

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12
Q

low urine specific gravity ex?

A

diabetes insipidus (dilute urine)

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13
Q

high specific gravity ex?

A

high urine osmolarity (concentrated) i.e. SIADH

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14
Q

orange urine from ?

A

meds i.e. pyridium in meds given to relieve sx in UTIs

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15
Q

yellow brown green urine

A

bilirubin

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16
Q

chemstrip only detects ?; will not detect ?

A

ionic solutes, glucose

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17
Q

acidic urine?
basic?
normal range?

A
  1. 5-5.5
  2. 5-8
  3. 5-8
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18
Q

basic urine seen w/ UTI from??

A

proteus!

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19
Q

renal glycosuria- ? is normal

A

plasma glucose (renal tubular dz is cause)

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20
Q

starvation or alc KA
ketones?
glucose?

A

positive

negative

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21
Q

nonpatho causes of ketones in urine?

A

low carb diet, fasting

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22
Q

chemstrip detects what protein?

A

albumin only

23
Q

what test detects all proteins? necessary for multiple myeloma!

A

protein electrophoresis

24
Q

two causes of ARF due to ATN with a positive chemstrip (4+) but NO INCREASED RBC?

A

rhabdomyolysis, acute hemolytic transfusion rxn

25
nitrite is gram .. ?
negative bacilli
26
leukocyte esterase detects? | positive = strong evidence of?
neutrophils (WBC) | UTI
27
bilirubin seen in chemstrip?
conjugated only (the only type in urine)
28
inc in almost all renal dz? | indicative of renal origin?
WBC | WBC Casts
29
inc WBC w/ neg bac culture ?
chlamydia urethritis
30
? produced by protein from tubular epithelium (Tamm-Horsfall protein); large number may be ?
hyaline casts | pathologic
31
most indicative of pyelonephritis?
WBC casts
32
renal tubular epithelial cell casts seems in ?
ATN
33
besides hallmark RBC casts, nephritic syn may have?
WBC, WBC casts
34
result from degeneration of cellular casts?, can be seen in?
granular casts | pyelonephritis
35
CRF casts?
waxy casts (were cellular, then granular, then lost ALL detail and became waxy)
36
crystals ususally?
insignificant
37
may represent contamination in diabetic patients ?
yeast
38
pear shaped flagellated parasite, motility is rapid, jerky, nondirectional?
trichomonas vaginalis
39
WBC count: | 50,000
``` Normal OA AI arthritis crystal-induced arthritis septic arthritis ```
40
mildest inc in WBC; noninflammatory?
OA
41
NEGATIVE birefringence w/ polarizing microscopy, monosodium urate crystals, needle-shaped
gout
42
rhomboid shaped crystals; POSITIVE birefringence
PSEUDOgout
43
transudate pleural effusion w/ ?
heart failure, cirrhosis (if uncomplicated)
44
``` transudate: appearance total protein pleural fluid lactate dehydrogenase (LDH) pleural fluid LDH/serum LDH ratio ```
clear, pale yellow <0.6 *** exudate pleural effusion opposite
45
workup of exudative pleural effusion? 4
cytologic studies, microbiologic studies, glucose, amylase
46
MCC ascites
cirrhosis
47
uncomplicated cirrhosis vs spontaneous bacterial peritonitis: - WBC 500 cells and >/=50% neutrophils? OR absolute neutrophils >250 - *inc WBC w/ lymphocyte predominance?
uncomp cirr bac peritonitis TB
48
tumor cells released into ascitic fluid? cancer implants i.e. ovarian ca
peritoneal carcinomatosis
49
malignant cells NOT directly released into ascitic fluid? not from cancer implants, from portal hypertension (not leaky vessels)
primary liver cancer
50
Cancer Males: #1 pleural fluid? ascitic? Females: pleural? ascitic?
lung, GI | breast, ovarian
51
``` to determine whether portal htn is present? High gradient (portal htn) causes? 3 Low causes (NOT portal htn)? ```
SAAG- serum to ascites albumin gradient - cirrhosis, alc hepatitis, massive liver mets, Budd Chiari syndrome, RHF, constrictive pericarditis - malignant peritoneal implants i.e. peritoneal carcinomatosis, peritoneal TB, pancreatitis, nephrotic syndrome
52
low pleural glucose causes (3)
malignancy, TB, lupus
53
lymph in abd cavity looks ? due to ?; suspect?
milky, triglycerides, lymphatic obstruction
54
TB 100% recovery w/?
histology and culture