Final-Renal&Synovial Flashcards

1
Q

most imp test of renal fxn

A

GFR

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2
Q

chemstrip is NOT sensitive enough for?

A

microalbuminuria

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3
Q

tea colored urine

A

post strep glomerulonephritis

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4
Q

minimal change dz nothing on ? only see damage to epithelial foot processes on ?

A

light microscopy

electron microscopy

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5
Q

goodpasture syndrome associated with?

A

pulm hemorrhage

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6
Q

RPGN- causes?

A

good pasteur, SLE, ANCA gene

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7
Q

RPGN- serology?

A

anti glomerular basement membrane Ab, dsDNA

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8
Q

sx include fever, chills, CVA tenderness

A

pyelonephritis

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9
Q

creatinine clearance requires

A

24h urine collection

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10
Q

nl GFR?

A

90-120

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11
Q

microalbumin checked for via ? OR ?

A

albumin/creatinine ratio, specimen: random urine sample during day

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12
Q

low urine specific gravity ex?

A

diabetes insipidus (dilute urine)

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13
Q

high specific gravity ex?

A

high urine osmolarity (concentrated) i.e. SIADH

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14
Q

orange urine from ?

A

meds i.e. pyridium in meds given to relieve sx in UTIs

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15
Q

yellow brown green urine

A

bilirubin

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16
Q

chemstrip only detects ?; will not detect ?

A

ionic solutes, glucose

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17
Q

acidic urine?
basic?
normal range?

A
  1. 5-5.5
  2. 5-8
  3. 5-8
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18
Q

basic urine seen w/ UTI from??

A

proteus!

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19
Q

renal glycosuria- ? is normal

A

plasma glucose (renal tubular dz is cause)

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20
Q

starvation or alc KA
ketones?
glucose?

A

positive

negative

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21
Q

nonpatho causes of ketones in urine?

A

low carb diet, fasting

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22
Q

chemstrip detects what protein?

A

albumin only

23
Q

what test detects all proteins? necessary for multiple myeloma!

A

protein electrophoresis

24
Q

two causes of ARF due to ATN with a positive chemstrip (4+) but NO INCREASED RBC?

A

rhabdomyolysis, acute hemolytic transfusion rxn

25
Q

nitrite is gram .. ?

A

negative bacilli

26
Q

leukocyte esterase detects?

positive = strong evidence of?

A

neutrophils (WBC)

UTI

27
Q

bilirubin seen in chemstrip?

A

conjugated only (the only type in urine)

28
Q

inc in almost all renal dz?

indicative of renal origin?

A

WBC

WBC Casts

29
Q

inc WBC w/ neg bac culture ?

A

chlamydia urethritis

30
Q

? produced by protein from tubular epithelium (Tamm-Horsfall protein); large number may be ?

A

hyaline casts

pathologic

31
Q

most indicative of pyelonephritis?

A

WBC casts

32
Q

renal tubular epithelial cell casts seems in ?

A

ATN

33
Q

besides hallmark RBC casts, nephritic syn may have?

A

WBC, WBC casts

34
Q

result from degeneration of cellular casts?, can be seen in?

A

granular casts

pyelonephritis

35
Q

CRF casts?

A

waxy casts (were cellular, then granular, then lost ALL detail and became waxy)

36
Q

crystals ususally?

A

insignificant

37
Q

may represent contamination in diabetic patients ?

A

yeast

38
Q

pear shaped flagellated parasite, motility is rapid, jerky, nondirectional?

A

trichomonas vaginalis

39
Q

WBC count:

50,000

A
Normal
OA
AI arthritis
crystal-induced arthritis
septic arthritis
40
Q

mildest inc in WBC; noninflammatory?

A

OA

41
Q

NEGATIVE birefringence w/ polarizing microscopy, monosodium urate crystals, needle-shaped

A

gout

42
Q

rhomboid shaped crystals; POSITIVE birefringence

A

PSEUDOgout

43
Q

transudate pleural effusion w/ ?

A

heart failure, cirrhosis (if uncomplicated)

44
Q
transudate:
appearance
total protein
pleural fluid lactate dehydrogenase (LDH)
pleural fluid LDH/serum LDH ratio
A

clear, pale yellow
<0.6
*** exudate pleural effusion opposite

45
Q

workup of exudative pleural effusion? 4

A

cytologic studies, microbiologic studies, glucose, amylase

46
Q

MCC ascites

A

cirrhosis

47
Q

uncomplicated cirrhosis vs spontaneous bacterial peritonitis:

  • WBC 500 cells and >/=50% neutrophils? OR absolute neutrophils >250
  • *inc WBC w/ lymphocyte predominance?
A

uncomp cirr
bac peritonitis
TB

48
Q

tumor cells released into ascitic fluid? cancer implants i.e. ovarian ca

A

peritoneal carcinomatosis

49
Q

malignant cells NOT directly released into ascitic fluid? not from cancer implants, from portal hypertension (not leaky vessels)

A

primary liver cancer

50
Q

Cancer
Males: #1 pleural fluid? ascitic?
Females: pleural? ascitic?

A

lung, GI

breast, ovarian

51
Q
to determine whether portal htn is present?
High gradient (portal htn) causes? 3
Low causes (NOT portal htn)?
A

SAAG- serum to ascites albumin gradient

  • cirrhosis, alc hepatitis, massive liver mets, Budd Chiari syndrome, RHF, constrictive pericarditis
  • malignant peritoneal implants i.e. peritoneal carcinomatosis, peritoneal TB, pancreatitis, nephrotic syndrome
52
Q

low pleural glucose causes (3)

A

malignancy, TB, lupus

53
Q

lymph in abd cavity looks ? due to ?; suspect?

A

milky, triglycerides, lymphatic obstruction

54
Q

TB 100% recovery w/?

A

histology and culture