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Host And Defense Exam 4 > Final Only - Weller - STDs > Flashcards

Final Only - Weller - STDs Flashcards

1
Q

Bacterial STIs? 5

A

Neisseria gonorrhoeae

Syphilis

Chlamydia trachomatis

Chancroid

Klebsiella

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2
Q

Viral STIs?

A

HIV

Genital warts/HPV

Herpes Viruses

Hep B

Hep C

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3
Q

Parasitic STIs?

A

Trichomonas vaginalis

Sarcoptes scabiei

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4
Q

Syndromes from STIs?

A

Pelvic inflammatory disease

Epididymis

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5
Q

What is urethritis?

A

Inflammation of urethra

-Common STIs in men

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6
Q

What is cervicitis?

A

Inflammation of the uterine cervix

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7
Q

What causes gonorrhea?

A

Neisseria gonorrhoaea
-G- diplodocus bacteria
—70-80% male to female transition and 20-30% female to male transition

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8
Q

What are symptoms of gonorrhea?

A

Asymptomatic to mildly symptomatic

Men
-Gonococcal urethritis is the most common manifestation of symptomatic infection

Women
-Discharge, abnormal bleeding, anorectal discomfort

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9
Q

What is the gold standard for dx of gonorrhea?

Tx?

A

Culture or PCR

Ceftriaxone, Cefpodoxime, Ciprofloxacin, Cefixime

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10
Q

What is chlamydia trachomatis?

A

Obligate intracellular bacteria - G- bacterium

PCR test

Tx - Azithromycin or doxycycline

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11
Q

What is haemophilus ducreyi?

A

G- coccobacillus

PCR is gold standard

Tx - Azithromycin, Ceftriaxone, Ciprofloxacin, Erythromycin

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12
Q

Tell me about syphilis.

A

Caused by spirochete Treponema pallidum
-Acquired sexually

Symptoms

  • Primary - Chancre
  • Secondary - Rash, swollen glands

Detection
-PCR

Tx
-Penicillin G benzathine

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13
Q

Tell me about Klebsiella granulomatis.

A

G-, rod-shaped bacterium

Symptoms (Usually in genitals)

  • Bleeding ulcers
  • Raised irregular edge of ulcer
  • Necrotic bad smell
  • Sclerotic lesion

Detection

  • Donovan bodies
  • PCR

Tx
-Azithromycin, erythromycin, doxycycline

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14
Q

Tell me about Trichomonas vaginalis.

A

Flagellated parasite
*Accounts for almost half of all curable STDs worldwide

Symptoms
-Infectious vaginitis

Features

  • Wet mount
  • PCR

Tx
-Single dose of metronidazole

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15
Q

Tell me about sarcoptes scabiei.

A

Itch mite

Symptoms
-Itching and no sleep

Features
-Burrows seen on skin scrapings

Tx
-5% permethrin cream

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16
Q

Tell me about genital warts.

A

HPV
*100 different types

Symptoms

  • Burning, itching, pain, and fullness
  • Many pts are asymptomatic

Tx

  • Surgery
  • Liquid nitrogen
  • Podofilox, podophyllin resin
17
Q

Tell me about herpes simplex virus types 1 and 2.

A

HSV-1 - Cold sores - 80% of population are carriers

HSV-2 - Genital herpes

Symptoms
-Primary Infection at mucosal site of inoculation w/ retrograde infection. Following resolution of primary infection, HSV remains in a latent state w/ intermittent reactivation at mucosal sites

Features
-PCR

Tx

  • Antiviral therapy for initial genital herpes
  • Daily suppressive therapy reduces frequency of recurrences
18
Q

T/F - HSV-2 and HIV are not on the CDC reportable infectious disease list. Gonorrhea and chlamydia are.

A

TRUE

19
Q

What are these viruses?

Human T cell lymphotropic virus (HTLV-1 and 2)

Hep C

Hep B (Hep D)

CMV

EBV

Molluscum contagiosum virus

A

Other sexually transmitted viruses

20
Q

What is PID?

A

Pelvic Inflammatory Disease

21
Q

Tell me about PID.

A

From N gonorrhoeae and C trachomatis

Symptoms
-Ascends from cervix or vagina to involve the endometrium and/or Fallopian tubes
—Infection can extend beyond the reproductive tract

Tx
-Ceftriaxone, doxycycline, metronidazole

22
Q

Tell me about epididymitis.

A

C trachomatis, n gonorrhoae

Symptoms
-Unilateral scrotal pain, tenderness, swelling, fever

Tx
-Ceftriaxone and then doxycycline

23
Q

Syphilis

Incubation period?

Early primary lesion?

No. Of lesions?

A

9-90 days

Papule

1

24
Q

Herpes

Incubation period?

Early primary lesion?

No. Of lesions?

A

2-7 days

Vesicle

Multiple

25
Q

Chancroid

Incubation period?

Early primary lesion?

No. Of lesions?

A

1-14 days

Pustule

Usually multiple and they may coalesce

26
Q

Donovanosis

Incubation period?

Early primary lesion?

No. Of lesions?

A

1-4 weeks (up to 6 months)

Papule

Variable

27
Q

AIDS is from what?

A

HIV 1 an d2

28
Q

Urethritis in males is from what?

A

N gonorrhoeae, c trachomatis, HSV, Mycoplasma genitalum, T vaginalis

29
Q

Epididymitis cause by?

A

C trachomatis, n gonorrhoeae

30
Q

Cystitis caused by?

A

C trachomatis, n gonorrhoeae, HSV

31
Q

Mucopurulent cervicitis is caused by?

A

C trachomatis, N gonorrhoeae, M genitalum

32
Q

Ulcerative lesions on the genitals is caused by?

A

HSV1, HSV2, treponema pallidum, haemophilus dcureyi, c trachomatis, klebsiella

33
Q

Genital and anal warts caused by what?

A

HPV

34
Q

Scabies is caused by?

A

Sarcoptes scabiei

35
Q

Tell me about oral gonorrhea.

A

Usually acquired via oral sex

May be asymptomatic or as sore throat

Rarely, small ulcers and mucosal erythema may occur in pts w/ pharyngeal gonorrhea infection

36
Q

Oral syphilis?

A

Fissured papules, wart like lesions

—Multiple spirochetes are found in the lesions

37
Q

T/F - Congenital syphilis can alter tooth and oral cavity development.

A

TRUE

Host And Defense Exam 4 (10 decks)

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