final exam-Table 1 Flashcards
What are 2 important diagnostic tests for anemia?
Reticulocyte count, Hgb
What does a high retic count with high bilirubin indicate?
Bone marrow is working!
Most likely d/t destruction or loss of RBCs (hemolytic)
(acute/chronic) anemias are well tolerated in children
Chronic
Anemic disorder characterized by bone marrow aplasia
Diamond Blackfan anemia
Your patient presents with anemia + Petechiae. You suspect:
Leukemia or HUS
Which lab would show you the presence of spherocytes?
Peripheral blood smear
When does Fe deficiency anemia first appear?
After the first 4-5 mo of life
What should you check if a pt presents with neutropenia or thrombocytopenia?
Bone marrow fxn
Name the iron studies for Fe Deficient anemia
Serum ferritin (low) Serum iron (low) Total iron binding capacity (inc) Transferrin saturation (low)
B-12 deficiency is a common finding in this GI disorder
Crohn’s
Smooth beefy red tongue may indicate
B-12 deficiency
Fanconi and Diamond-Blackfan anemias are ____ forms of normocytic anemia
Congenital
____ can cause acquired normocytic anemia
Parvo B19
What is TAR and what condition is it found in?
Thrombocytopenia with absent radius. Fanconi anemia
Spherocytosis is inherited this way
Autosomal Dominant
____ anemias are characterized by Anemia, Jaundice, Splenomegaly
Hemolytic
Longstanding spherocytosis and sickle cell disease can cause _____
Gallstones
What is the most common inherited enzyme defect?
G6PD deficiency
G6PD commonly presents with this finding
Hyperbilirubinemia
This hemoglobinopathy is found in carriers only
Thalassemia trait
Thalassemia minor is a type of _____ thalassemia
Beta
Hemophilias, vitamin K deficiency, and DIC are all disorders of _____
Coagulation
Intrinsic clotting pathway is measured by a
PTT
Extrinsic pathway measured with a
PT
A pt who is bleeding into their joints should be worked up for
Hemophilia
More common mechanism of thrombocytopenia
Increased consumption/ breakdown of RBCs
____ is a type of thrombocytopenia associated with severe illness or shock
DIC
Most common bleeding disorder of CHILDhood
ITP
ITP usually shows up after____
A viral infection