Final: Circulatory System Slides Flashcards

1
Q

Components of cardiovascular system

A

Closed system that consists of the heart, blood vessels, and blood

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2
Q

Functions of cardiovascular system (3)

A
  • Heart pumps blood (to deliver it)
  • Blood vessels provide path for blood to travel
  • Blood carries nutrients to organs and picks up wastes
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3
Q

What does it mean the cardiovascular system is closed?

A

Blood always contained in the blood vessels; and the blood itself is not exchanged (only the contents)

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4
Q

Pulmonary circuit

A

Short distance; communication between heart and lungs; delivers deoxygenated blood from heart to lungs

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5
Q

Systemic circuit

A

Long distance; moves nutrients throughout the body; delivers oxygenated blood from heart to body

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6
Q

Blood coming to cells is _____ oxygenated and blood leaving cells is ____ oxygenated

A

Richly, poorly

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7
Q

Blood coming to lungs is _____ oxygenated and blood leaving lungs is _____ oxygenated

A

Poorly, richly

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8
Q

What happens when cardiac muscles of heart contract?

A

Blood physically ejected from heart as muscles work against a load/weight (the blood)

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9
Q

What are the atria?

A

Receiving chambers; where blood enters

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10
Q

What are the ventricles?

A

Pumping chambers; blood leaves the heart from here to the blood vessels

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11
Q

What are valves?

A

Flaps of connective tissue that guide blood in the right direction in the heart; prevent blood from flowing backwards

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12
Q

Location of tricuspid valve

A

Between right atrium and right ventricle

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13
Q

Location of bicuspid valve

A

Between left atrium and left ventricle

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14
Q

Location of pulmonary semilunar valve

A

Between right ventricle and pulmonary trunk

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15
Q

Location of aortic semilunar valve

A

Between left ventricle and aorta

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16
Q

Main blood vessels in heart (5)

A

Superior vena cava, inferior vena cava, pulmonary trunk, pulmonary veins, aorta

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17
Q

Superior vena cava function

A

Bring deoxygenated blood from all structures above diaphragm to the right atrium

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18
Q

Inferior vena cava function

A

Bring deoxygenated blood from all structures below diaphragm to right atrium

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19
Q

Pulmonary trunk function

A

Take deoxygenated blood from right ventricle to lungs (branches off, one branch for each lung)

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20
Q

Pulmonary veins function

A

Bring back oxygenated blood from lungs to left atrium

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21
Q

Aorta function

A

Deliver oxygenated blood from left ventricle to body (biggest blood vessel; delivers blood all over)

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22
Q

Path of blood through the heart

A

Poorly oxygenated blood from body enters heart through SVC or IVC - right atrium - tricuspid valve - right ventricle - pulmonary semilunar V - pulmonary trunk - lungs - richly oxygenated blood enters heart through pulmonary veins - left atrium - bicuspid valve - left ventricle - aortic semilunar valve - aorta - body (then repeat)

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23
Q

What is ventricular diastole? Which valves are open/closed?

A

Ventricles are relaxed and filling with blood

  • Bicuspid and tricuspid valves are open
  • Aortic and pulmonary valves are closed
24
Q

What do you hear in a heart beat?

A

Valves closing: first bicuspid and tricuspid, then aortic and pulmonary (one diastole and one systole)

25
What is ventricular systole? Which valves are open/closed?
Ventricles contracting to eject blood - Bicuspid and tricuspid valves closed - Aortic and pulmonary valves open
26
What initiates heart activity (how does it contract)?
Specialized pacemaker cells that generate their own electrical activities
27
What structures of the heart do pacemaker activities go through (in order)?
1. Sinoatrial node (starts process) 2. Atroventricular node 3. Bundle of His (reaches apex) 4. Bundle of branches 5. Purkinje fibers
28
What direction do ventricles contract in?
Bottom to top
29
Order of contraction
Atria then ventricles
30
Location of sinoatrial node (SA)
Right atrium
31
Location of atrioventricular node (AV)
Interatrial septum
32
Location of bundle of His
Interventricular septum
33
Location of Purkinje fibers
Ventricular walls
34
How do right and left ventricles contract simultaneously?
Lots of gap junctions in cardiac muscle fibers (allow movement of action potentials)
35
How do we know the heart is working properly?
Electrocardiogram (minimally invasive) used to record electrical activities of the heart
36
How does an electrocardiogram work?
Patient connected to electrodes - EKG/ECG machine picks up collective action potential
37
Parts of one trace of electrocardiogram
P wave: atria contraction/depolarization QRS complex: ventricular contraction/depolarization T wave: ventricular relaxation/repolarization
38
Types of blood vessels (5) and order of flow after leaving heart
Arteries - Arterioles - Capillaries - Venules - Veins
39
Which structures correspond to which parts of ECG?
SA and AV: P wave Bundle of His: dip before P wave Purkinje fibers: QRS complex
40
What are arteries?
Strong elastic vessels that carry blood away from the heart and branch into smaller arterioles
41
What are veins?
Carry blood back to the heart, have thinner walls than arteries, branch into smaller venules
42
Layers of arteries and veins (4)
Tunica externa, tunica media, tunica interna/intima, lumen
43
What is the tunica externa?
Connective tissue with elastic and collagen fibers
44
Tunica media structure and function
Made of smooth muscles; mediates vasoconstriction and vasodilation
45
Tunica interna/intima structure and function
Made of simple squamous epithelium (endothelium); provide smooth surface for blood to pass through (minimize friction)
46
Structural differences between arteries and veins (3)
Arteries have smaller lumen and thicker tunica media; only veins have valves; arteries are high pressure because they receive blood directly from the heart
47
Capillary function and structure
Smallest diameter blood vessels Made of endothelial layer only; have slits (thinness facilitates gas diffusion/exchange) Site of gas exchange with cells
48
What is involved in microcirculation?
Arterioles (oxygen-rich), capillaries (gas exchange), venules (oxygen-poor)
49
In [gas] exchange between capillaries and cells, which substances go where?
O2 and glucose go from capillary to cell, and CO2 goes from cell to capillary
50
Veins have ___ ____ and therefore hold the majority of the blood
Low pressure
51
How do skeletal muscles help veins return blood to the heart?
Skeletal muscle contraction squeezes veins and helps them push blood back to heart (working against gravity)
52
Blood composition
Fluid connective tissue made of cellular components (erythrocytes, leukocytes, platelets) suspended in plasma fluid
53
Plasma composition
Water, proteins that exert osmotic pressure, minerals and electrolytes
54
Plasma proteins (and their functions)
Albumins: transport proteins Globulins: immune function Fibrinogen: clotting function (minimize blood loss)
55
Erythrocyte function and location of synthesis
Transport gases (O2, CO2) in body; produced in bone marrow
56
Erythrocyte structure
Biconcave discs, lack organelles, short life span (~120 days), packed with hemoglobin (bound to iron); formation depends on folic acid and B12 vitamins
57
What regulates erythrocytes?
Erythropoietin, a hormone released by the kidney that acts on bone marrow to replace/release red blood cells as needed