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Hemotology > Final > Flashcards

Final Flashcards

1
Q

What kind of testing is an ESR?

A

Screening

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2
Q

The ESR is directly proportional to what?

A

Red blood cell mass

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3
Q

What factors affect the ESR?

A

Red blood cells, plasma, mechanical/technical

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4
Q

Larger and smaller cells affect the ESR how?

A

Larger cells fall faster smaller cells and settle more quickly

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5
Q

What dyes are used for a wright stain?

A

Eosin and methylene

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6
Q

How many slides do you look at for a reticulocyte test?

A

2

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7
Q

How do you determine the absolute retic count?

A

Retic percent in decimal form times red blood cell count

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8
Q

What can cause decreased reticulocyte count?

A

Aplastic anemia
exposure to radiation
chronic infection
certain medications

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9
Q

What can cause an increased reticulocyte count?

A 
Rapid blood loss 
high elevation 
hemolytic anemia
certain medications 
pregnancy
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10
Q

What is the difference between a manual white blood cell count in a manual platelet count?

A

Average # /(.01x.1x9) for wbc

Average # /(.01x.1x9) for platelets

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11
Q

What are the quantitative test for platelets?

A

Platelet count

peripheral smear

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12
Q

What does in vivo mean?

A

Measurement of platelet function when vascular some endothelium is injured

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13
Q

What is a clot retraction test?

A

What is allowed to clock in glass tube. Degree of clot retraction is limited by fiber and contractions of the hematocrit. Degree of retraction is directly proportional to the number of platelets and inversely proportional to the hematocrit and amount of fibrinogen

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14
Q

Platelet adhesion test does what?

A

Runs blood through a column of glass platelets are checked before and after to see difference

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15
Q

How does a platelet aggregation test done

A

Platelet rich plasma treated with known aggregating agent is measured with light. As the plasma becomes more turbine less light comes through

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16
Q

Platelet factor three and platelet factor four are what?

A

Antiplatelet antibodies

17
Q

What does aspirin do to clotting?

A

It prevents the adding of coming clooxygenase 1

18
Q

What does thromboxaneA2 do?

A

It stimulates the activation of new platelets as well as assist with aggregation

19
Q

What is primary hemostasis?

A

Blood vessel response (vasoconstriction) platelet response (forming a platelet plug)

20
Q

What is the difference between serum and plasma?

A

Serum is the fluid component that does not play a role in clotting. Plasma is everything else

21
Q

What does the Buffy coat contain?

A

White blood cells and platelets

22
Q

What are the platelet granules?

A

Alpha, Delta, lysosomes

23
Q

What is the Alpha granule responsible for?

A

They are the most abundant they are secreted not released participate and adhesion, aggravation, plasma Coag

24
Q

What are delta granules responsible for?

A

Serotonin: vasoconstrictor

ADP: activate platelet a TP: energy calcium: secondary coagulation released not secreted

25
Q

What are lysosomes are responsible for?

A

Hydrolase enzymes that digest vessel walls and debris like dead epithelial cells

26
Q

What is a delta check?

A

Comparing current patient values to previous ones to detect discrepancies

27
Q

What differentiates a promyelocyte from myelocyte?

A

Nucleus is slightly indented chromatin is more dense red purple and more coarse and clumped

28
Q

What is Cyanmethemoglobin?

A

And alternative way to measure hemoglobin that causes the hemoglobin to oxidize into methemoglobin

29
Q

The absorbance of Cyanmethemoglobin at how many in nm is directly proportional to the hemoglobin concentration?

A

540

30
Q

What is the reagent of Cyanmethemoglobin?

A

Cyanide

31
Q

What is the glycolytic pathway?

A

Glycolysis the generation of ATP turning glucose into pyruvate and lactate

Hemotology (9 decks)

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