final Flashcards
def of disease
disturbance of body structure or funktion
organic disease
structural changes
gross and histologic examination
funktional disease
no structural change
funktions are disturbed
pathology
study of disease
etiology
cause of disease
signs
objective manifestations (measurable) swelling or fever
symptoms
subjective manifestations
pain or weakness
idiopathic
unknown cause
iatrogenic
caused by prescribed treatment
nosocomial
aquired from a hospital
classifications of diseases
congenital and hereditary inflammatory degenerative metabolic neoplastic
congenital and hereditary disease
result of development disturbances
genetic abnormalities, chromosome
inflammatory disease
body reacts to injury through inflammatory process
degenerative disease
tissue or organ degeneration as result of aging or breakdown
metabolic disease
disturbance in metabolic process in body
neoplastic disease
uncontrolled cell growth that leads to formation of tumors
diagnosis
identifying a disease and its course
clinical history
physical exam
differential diagnosis
prognosis
outcome of disease
specific or symptomatic treatment
components of physical exam
observation
auscultation
palpation
nucleus
contains DNA and RNA
directs metabolic funktion of cells
mitochondria
power house of the cell
use nutrients to make ATP
epithelium
covers outside of body
lines body cavities, glands
protection, absorption, secretion
connective tissue
contain protein fibers, flexible
elasticity, stretch and recoil
muscle tissue
contraction
nervous tissue
transmit nerve impulses-communication
atrophy
reduction in cell size in response to diminshed funktion, hormonal stimulation, reduced blood supply
hypertrophy
increase cell size
hyperplasia
increase in number of cells in response to demand
metaplasia
change from one type of cell to another
dysplasia
cell development and maturation are disturbed and abnormal
mitosis
somatic cells
2 genetically identical daughter cells
meiosis
egg and sperm
gentically different
dominant gene
homozygous or heterozygous state
BB or Bb
recessive gene
homozygous state
bb
signs of inflammation
heat
redness
swelling
pain
humoral immunity
production of antibodies
main defense against bacteria and bacterial toxins
cell mediated immunity
formation of lymphocytes that attack and destroy foreign material
main defense against viruses, fungi, parasites
rejects transplanted organs
eliminated abnormal cells
pathogenesis of autoimmune disease
alteration of patients own self antigens causing them to become antigenic = immune reaction
formation of cross reacting antibodies against foreign antigens
defective regulation of immune response
pathogenic microorganisms
bacteria rickettsiae mycoplasma viruses fungi
bacteria
shape and arrangement gram stain biochemical and growth characteristics antigenic structure streptococci and staphococci treat with antibiotics
rickettsiae
obligate intracellular parasites
insects transmitted to human via bite
rocky mountain spotted fever
virus
smallest infectious agents capsid with DNA or RNA attachment to cells relies on host inclusion bodies chicken pox and shingles
mycoplasma
free living bacteria
no cell wall
not responsive to antibiotics
atypical pneumonia
fungi
yeasts and molds
forms hyphae
athletes foot
def of communicable disease
disease transmitted from person to person
methods of transmission of communicable disease
direct-physical contact or cough or sneeze
indirect-contaminated food or water, insects
effective control of communicable diseases
must break transmission to eradicate or control disease
immunization
identify, isolation, treatment
factors in congenital malformations
chromosomal abnormalities
abnormalities of individual genes
intrauterine injury to embryo or fetus
environmental factors
diseases of chromosomal abnormalities
nondisjunction trisomy 21 monosomy deletions translocations
benign
slow growth rate
expansion
tumor remains localized
well differentiated-normal appearance
malignant
rapid growth rate
metastasis
infilteration
poorly differentiated
treatment for cancer
surgery radiotherapy hormones anticancer drugs adjuvant chemo immunotherapy
hemophilia
sex linked genetic blood coagulation disease
atria
recieve blood
ventricles
pump out blood
coronary heart disease
arteriosclerosis of arteries
arteries narrow due to fatty materials
form crystals and necrosis- mushy yellow
risk factors of coronary heart disease
elevated blood lipids
high blood pressure
smoking
diabetes
funktion of respiratory system
oxygenates blood and removed co2
supply cells with 02
site of gas exchange in lungs
alveoli
diseases of COPD
pulmonary emphysema
chronic bronchitis
2 main female sex hormones
estrogen progesterone
female reproductive diseases
cervicitis PID salpingitis condylomas endometriosis
biggest concern of female reproductive diseases
PID and sterility
PID
inflammation of fallopian tubes and ovaries
funktional unit of kidney
nephron
urinary disease associated with
inadequate blood filteration
kidney funktions
excrete wastes
regulate mineral and water balance
produce erythropoietin and renin
glomerulonephritis
inflammation of glomeruli by antigen-antibody reaction
beta
nephrotic syndrome
marked loss of proteins in urine
cystitis
affects only bladder
produce sperm
testes
funktions of liver
metabolism
synthesis
storage
detoxification
funktion of gastrointestinal tract
digestion of food and absorption of nutrients into bloodstream
major endocrine glands
pituitary thyroid parathyroid adrenal cortex and medulla pancreatic islets ovaries and testes
hyperthyroidism
toxic goiter or graves disease
mimics effects of TSH but not subject to normal control mechanism
hypothyroidism
adult: myxedema-metabolic slowing
infant: cretinism-impaired growth and nervous system-low metabolism
3 mechanisms of hormone secretion
blood level of hormone
nervous system
other hormones
what causes type 1 diabetes mellitus
inadequate insulin secretion by pancreas
damage pancreatic islets
autoantibodies
components of CNS
brain and spinal cord
frontal lobe funktions
mood, personality, voluntary movement
parietal lobe funktions
general sensory reception
temporal lobe funktions
hearing
occipital lobe funktions
vision
spongy bone
thin columns of bone- trabeculae
large spaces between trabeculae filled with red bone marrow
site of blood cell formation
compact bone
repeating circular units called osteons
no spaces
long bone structures
shaft
ends
epiphyseal plate or line
periosteum
funktion of skeletal muscle
myofilaments slide together
nerve stimulation
muscular dystrophy
progressive degeneration and weakening of muscles
muscles unable to store protein and replaced with fat and connective tissue
sex linked recessive