Final Flashcards

1
Q

How do you determine the cause of a disease?

A

Koch’s postulate

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2
Q

Relative ability of a pathogen to cause disease

A

Virulence

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3
Q

Pathway of pathogenesis

A

Exposure; Adherence: Invasion: Infection: Toxicity or Invasiveness: Disease

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4
Q

Presence of bacteria in the blood stream

A

Bacteremia

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5
Q

Bloodborne systemic infection

A

Septicemia

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6
Q

Molecules produced by organisms to increase pathogenicity

A

Virulence factors

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7
Q

Virulence factor pathogens produce enzymes that

A

Enhance virulence by breaking down or altering host tissue to provide access to nutrients; protect the pathogen by interfering with normal host defense mechanisms

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8
Q

Give an example of a virulence factor

A

Salmonella

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9
Q

Proteins released from pathogen cell as it grows

A

Exotoxin

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10
Q

Three categories of exotoxins

A

Cytotoxins, AB toxins, Suprantigen toxins

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11
Q

Compare/Contrast Innate and Adaptive Immunity

A

Innate: Nonspecific, non-inducible, does not need previous exposure
Adaptive: Dependent of previous exposure
T cells and B cells

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12
Q

Nonspecific reaction to noxious stimuli

A

Inflammation

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13
Q

Biocontrol heat

A

Kills by oxidation

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14
Q

Autoclave

A

Kills microbes and spores at 121C

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15
Q

Pasteurization

A

Heat sensitive liquids; 63C, 72C

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16
Q

Radiation

A

Light to sterilize and disenfect

17
Q

Depth filtration

A

Sheets or mats of fibrous paper, cellulose or glass

18
Q

Membrane filters

A

Sterilization, uniform pore size

19
Q

Antimicrobials that inhibit microbial growth without killing them

A

-static

20
Q

antimicrobials that kill microbes

A

-cidal

21
Q

Antimicrobials that kill microbes by lysing them

A

-lytic

22
Q

Advantages of a biofilm

A

Trap nutrients for growth, prevent detachment of cells, self defense, live close together