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NeuroBiology > Final > Flashcards

Final Flashcards

1
Q

Mental Disorders:

What are four types of anxiety disorders?

A
  1. Panic Disorder
  2. Phobia (EX. Agoraphobia)
  3. OCD
  4. PTSD
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2
Q

Mental Disorders:

What are the 6 types of treatments of affective disorders?

A

1.Psychotherapy
2.Antidepressants
3.Electroconvulsive Therapy
4.Deep Brain Stimulation
5.Ketamine
6.Lithium

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3
Q

Mental Disorders:

What are the four types of neurodegerative Diseases?

A
  1. Alzheimers Disease
  2. Parkinsons Disease
  3. Amyotrophic Latera Sclerosis
  4. Huntington’s Disease
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4
Q

Mental Disorders:

Based on these symptoms what neurodegenerative disease can we predict?
Symptoms: Forgetfulness, loss of abstract thinking, judgement, and tasks. Personality changes.

A

Alzheimers Disease

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5
Q

Mental Disorders:

What are the two types of Alzheimers Disease?

A
  1. Sporadic AD
  2. Familial AD
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6
Q

Mental Disorders:

Which Alzheimers Diseases is the rarest form ?

A

Familial AD

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7
Q

MDD & Happiness:

Which diffused modulatory system controls regulation of attention, arousal, and sleep–
wake cycles as well as learning and memory,
anxiety, and pain, mood, and brain metabolism?

A

Norepinephrine System

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8
Q

MDD & Happiness:

Which diffused modulatory system does this pertain to “ Arouse and awaken the forebrain, control mood,and certain emotional behavior” ?

A

Serotonin System

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9
Q

MDD & Happiness:

Which diffused modulatory system does this pertain to “ Regulation of mood, and movement. Part of the reward system, but not only about rewards. “ ?

A

Dopamine System

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10
Q

MDD & Happiness:

There are two aspects of happiness which one is responsible for pleasure?

A

Hedonia

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11
Q

MDD & Happiness:

There are two aspects of happiness which one is responsible for a well lived life?

A

Eudaimonia

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12
Q

MDD & Happiness:

Which major for many mental illness symptom does this pertain to “ lack of pleasure”?

A

Anhedonia

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13
Q

MDD & Happiness:

Which pleasure is driven by mesotelencephalic dopaminergic pathway?

A

Anticipatory

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14
Q

MDD & Happiness:

Which pleasure is driven by both dopamine and opiod receptor activation?

A

Consumatory

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15
Q

MDD & Happiness:

The dompamine system has a region known as NAc (Nucleus Accumbens) what is this area responsible for?

A

Motivation and goal directed behavior

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16
Q

Language:

Which procedure was used to determine that the left hemisphere is dominant for speech?

A

WADA Procedure

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17
Q

Language:

What area of the brain is this “Left region frontal lobe responsible for speech articulation”?

A

Broca’s area

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18
Q

Language:

What area of the brain is this “Superior surface of left temporal lobebetween auditory cortex and angular gyrus, lesions disrupt normal speech.” ?

A

Wernickes Area

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19
Q

Language:

Primary Type of Aphasia: If someone has this aphasia there will be
-Difficulty speaking, but understand spoken/heard
language
– Paraphasic errors
– Pause to search for words, repeat “overlearned” things, difficulty repeating words

A

Broca’s Aphasia (motor, nonfluent aphasia)

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20
Q

Language:

Primary Type of Aphasia: If someone has this aphasia there will be
Symptoms: Mixture of clarity and gibberish, undisturbed by sound of own or other’s speech
Characteristics: Correct words in incorrect sequence, incorrect word similar to correct word

A

Wernicke’s (receptive) aphasia
(Fluent speech, poor comprehension)

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21
Q

Language:

Which studies removed corpus collusum (main fibers connecting the brain) optic chiasm input from left field is processsed in the right hemisphere but since its removed the right hemisphere cannot send information to the left side?

A

Split Brain Studies (Sperry)

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22
Q

Language:

Speech irregularities
result from stimulation of two other
site, What are those two other sites?

A
  1. posterior parietal lobe near
    the Sylvian fissure
  2. Temporal lobe
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23
Q

Language:

Language studies using brain stimulation uses NAGMRJ what does this stand for ?

A
  • N – naming difficulties
  • A – arrested speech
  • G – Grammatical errors
  • M – Facial tics
  • R – Reading failures
  • J – Jargon
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24
Q

Language:

FOXP2, CNTNAP2, and KIAA0319 are all what kind of mutations?

A

Specific Language Impairment

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25
Q

Dyslexia: a learning disorder characterized by difficulty reading due to problems identifying speech sounds and learning how they relate
to letters and words; appears to have strong genetic link. What gene is it stroongly correlated to?

A

KIAA0319

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26
Q

Brain Rhthyms:

What are 6 of the brain rhthyms?

A

1.Gamma
2.Beta
3.Alpha
4.Mu
5.Theta
6.Delta

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27
Q

Brain Rhthyms:

What brain rhthyms is categorized at 25-100 Hz and is active thought?

A

Gamma

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28
Q

Brain Rhthyms:

What brain rhthyms is activated cortex and categorized at 14-20 Hz and is state is alert, working?

A

Beta

29
Q

Brain Rhthyms:

What brain rhthym is categorized as a quiet walking state causing daydreaming and creativity at 8-13Hz making you relaxed and reflective?

A

Alpha

30
Q

Brain Rhthyms:

which rhthym is similar to alpha, largest over
motor and somatosensory areas?

A

Mu

31
Q

Which brain rhthym is at 4-7Hz causong some sleep states making you drowsy and meditative?

A

Theta

32
Q

Brain Rhthyms:

Which brain rhthym will show less than 4Hz is at deep sleep causing you to be sleepy & dreaming?

A

Delta

33
Q

Brain Rhthyms:

What oscillation occurs when sleeping and receives thalamus input?

A

Spindles

34
Q

Brain Rhthyms:

What oscillation occurs in brief episodes in the hippocampus?

A

Riples

35
Q

Brain Rhthyms:

*blank *are created by the thslamus pacemaker

A

Spindles

36
Q

This synchronized oscillation mechanism is generated in the thalamus(pacemaker) then to massive corical input influencing the cortex, what pacemaker is this?

A

Central Clock Pacemaker

37
Q

What are the four waves of sleep?

A

1.N1
2.N2
3.N3
4.N4

38
Q

Which sleep wave is alpha rhthyms of sleep?

A

N1

39
Q

Which sleep wave is a spindle from the thalamus pacemaker causing no eye movement?

A

N2

40
Q

Which sleep wave is a slow delta rhthym?

A

N3

41
Q

*

Which sleep wave is the deepest sleep stage at 2Hz or less EEG rhthym?

A

N4

42
Q

“Hallucinating brain in paralyzed body”

A

REM Sleep

43
Q

“Idling brain in a movable body”

A

Non-REM sleep

44
Q

-Critical neurons Diffuse modulatory neurotransmitter systems (controls thalamus)
– General decrease in firing rates of most modulatory neurons.
– Noradrenergic and serotoninergic neurons: Fire during and enhance waking state
– Cholinergic neurons: enhance REM events
– Serotonin from raphe nuclei decreased during REM sleep
– REM sleep: Limbic system and extrastriate cortex more active. Frontal lobes less
active.
– Hypocretin (Orexin) peptides (neurotransmitters) promote wakefulness, inhibit REM
sleep. Secreted by hypothalamus

A

Neural Mechanisms of Sleep

45
Q

What are the four types of sleeping disorders ?

A
  1. Insomnia
  2. Sleep Apnea
  3. Restless Leg Syndrome
  4. Narcolepsy
46
Q

Which sleep disorder causes a disorder
causing unpleasant crawling, prickling,
or tingling sensations in the legs and
feet, and an urge to move them about for
relief?

A

Restless leg syndrome

47
Q

Which sleep disorder is interrupted breathing
during sleep. Mostly in obese individuals.?

A

Sleep Apnea

48
Q

Which sleep disorder has many causes and is the inability to sleep?

A

Insomia

49
Q

blank patients often have less hypocretin
(orexin) neurons in the lateral hypothalamus.

A

Narcoleptic

50
Q

Memory:

Damage to diencephalon
leads to blank

A

amnesia

51
Q

Memory:

Lesions cause “blank”

A

anterograde amnesia

52
Q

Memory:

Which memory syndrome is caused by chronic alcoholism
* Characterized by confusion, memory impairments, and apathy
* Patients usually have lesions in dorsomedial thalamus?

A

Korsakoff’s syndrome

53
Q

Memory:

Which experiment was used in behavioral neuroscience for studying neural mechanisms of spatial learning and memory?

A

Morris Water Maze

54
Q

What part of the brain is required for spatial memory?

A

Hippocampus

55
Q

Lesions to striatum disrupt
procedural memory (habit learning)

A

Nondeclarative Memory

56
Q

caudate nucleus and
putamen of basal ganglia (control
voluntary movement) is whar

A

statium

57
Q

“train to recognize card patterns” is an example of what memory?

A

Nondeclarative memory

58
Q

Synaptic Plasticity in the Hippocampus: LTD causes ___ frequency stimulation weaking synapse

A

low

59
Q

Which memory is based off facts and events in one’s life
– Episodic (events) or Semantic (facts)?

A

Declarative Memory

60
Q

Which memory is – Procedural memory based off skills, habits?

A

Nondeclarative memory

61
Q

Declarative Memory triggers what parts of the brain?

A

Medial Temporal lobe & Diencephalon

62
Q

NOnDeclarative Memory triggers what parts of the brain?

A

Striatum, Cerebellum, Amygdala

63
Q

What disorder causes Serious loss of memory and/or ability to learn?

A

Amnesia

64
Q

What kind of amnesia makes you Forget things you already knew?

A

Retrograde Amnesia

65
Q

What kind of amnesia causes the Inability to form new memories?

A

Anterograde Amnesia

66
Q

Which theory is this External events (sensory inputs) are represented by cortical cells
– Cells reciprocally interconnected:
Cells that fire together, wire together
Cells out of sync lose their link
Supports the concept of “distributed memory”?

A

Hebbs theory on plasticity

67
Q

What experiment is this “Chemical switch to activate Channelrhodopsin-2 (ChR2) expression in few
activated hippocampal neurons (engram neurons recruited by sensory information of the context).
* ChR2 activated by blue light later on in a different context to reactivate the memory of previous context and reconsolidate with the new context.”

A

Creating false memories

68
Q
  1. Correlated pre- and post-synaptic
    activities cause synapse
    strengthening and stabilization.
  2. Uncorrelated pre- and post-synaptic
    activities cause synapse weakening
    and their elimination (Corollary)
A

hebbs rule

NeuroBiology (8 decks)

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