Final 15-17 Flashcards
What are the functions of the endocrine system?
to communicate between cells
maintain homeostasis
integrate cellular activity using hormones
How does the endocrine system function?
It functions with cooperation between neural impulses and hormone to stimulate the production of chemical messengers that make target cells do work in order to maintain homeostasis.
what are the main parts of the endocrine system?
hypothalamus glands and other organs.
What are the similarities of the endocrine system in comparison to neural activity?
- use chemicals at some point to exchange information.
- communicate between cells
- maintain homeostasis
What are the differences of the endocrine system and neural activity?
- nervous system uses neurotransmitters and endocrine uses hormones.
- nervous system activity is temporary while endocrine is longer lasting.
- nervous system is takes milliseconds to react whereas endocrine takes minutes to hours to act
- information travels down the axon and in between neurons but endocrine uses the blood system to transport it’s chemical information.
- in neuronal system Target cells are neurons target cells in the endocrine can be anywhere and everywhere are where ever just depending on the hormone released.
what are hormones generally
they are chemicals produced by neurons glands and organs that help maintain homeostasis.
how hormones reach their target cells
bloodstream
what are the function of hormones in general
they are used to regulate
- circadian rhythms
- chemical composition and volume of water
- metabolism
- contraction of smooth muscle
- immune function
- growth and development
- reproduction
what are the three reasons for hormone release?
humoral
neural
hormonal stimulation
what is humoral stimulation?
changes of composition of blood or fluids of the body
neural stimulation?
sympathetic stimulation of adrenal medulla
Hormonal stimulation
anterior pituitary glands stimulating other endocrine glands to work.
what is a feedback system in the body?
a feedback system is one that shuts off an action once the system that the job has completed, whether that is that the body was once hot and now it is cool or blood levels are now at a good level.
are negative feedback systems or positive feedback systems more common?
negative feedback because they do things to combat a stimulus.
do all hormons work on all cells?
no the cell needs to havethe same type of receptor that the hormone carries inorder for the hormone to stimulate the cell to do anything.
Which organ can be described as the master controller of the endocrine system?
hypothalamus
what are the three ways that the hypothalamus structure controls endocrine function
- produces hormones released by the posterior pituitary ADH oxytocin
- PRODUCES RELEASING HORMONES AND INHIBITING HORMONES THAT ARE SENT TO THE ANTERIOR PITUITARY VIA THE HYPOPHYSEAL PORTAL SYSTEM CONTROLLING THE RELEASE OF HORMONES CONTROLLING OTHER ENDOCRINE ORGANS.
-CONTAINS ANS NEURON CELL BODIES WHOSE AXONS TRAVEL TO THE ADRENAL MEDULLAE AND WHEN SYMPATHETIC ACTIVATION OCCURS, CAUSE THE ADRENAL MEDULLAE TO RELEASE NOREPINEPHRINE AND EPINEPHRINE
what are the parts of the pituitary gland?
anterior and posterior
what is the medical name for the anterior lobe of the pituitary gl
adenohypophysis
what are the type of cells found in the anterior lobe of the pituitary gland
glandular cells
what is the medical name for the posterior lobe of the pituitary gland
neurohypophysis
what are the type of cells found in the posterior section of the pituitary gland
axon terminals extending from the hypothalamus
what is the infundibulum?
THE CONNECTION PORTAL BETWEEN THE HYPOTHALAMUS AND THE PITUITARY GLAND
what runs through the infundibulum
axons back and forth to the hypothalamus and the anterior pituitary also the HYPOPHYSEAL PORTAL SYSTEM
what is the hypophyseal portal system
a specialized blood system
which is designed specifically to pick up hormones from the hypothalamus and taking them to the anterior pituitary and picking up hormones already produced from the pituitary.
how is the anterior pituitary controlled?
It is controlled by hormones. when there needs to be an uptick in production the hypothalamus sends hormones and when it needs decrease in hormones it releases inhibitory hormones.
how is the posterior pituitary controlled?
AXONS EXTENDING FROM THE HYPOTHALAMUS TO THE POSTERIOR PITUITARY GLAND RELEASE THEIR HORMONES INTO A CAPILLARY BED SURROUNDING THE PP.
Where are the hormones of the hypothalamus made?
inside the cell bodies of the neurons
what are the six hormones synthesized by the AP?
TSH ATCH FSH PRL GH LH
LH
LUTENIZING HORMONE regulates functions of testes and ovaries
TSH
Thyroid stimulating hormone self explanatory bitch
ATCH
adrenocorticotropic hormone
stimulates adrenal cortex hormone production
FSH
follicle stimulating hormone regulate reproductive functions testis and overies
PRL
prolactin; stimulates mammary gland development and milk production
GH
Growth hormone; regulate growth and metabolism
What causes each of the hormones to be produced in the AP.
five produced by receiving stimulating hormone
-prolactin stimulated by decrease of inhibiting hormone
what are the two hormones produced by the PP
ADH and oxytocin
where are the hormones of the PP made?
hypothalamus but they are released in the posterior pituitary.
why is ADH an important hormone
- controls water balance
- allows us to reclaim water from being lost as urination
- it increases blood pressure by increasing blood volume by taking it from the urine and putting it back into the bloodstream
What is ADH’s target
kidneys
what happens if vasopressin is not secreted(ADH)
your bladder will be filled with a bunch of undiluted urine and there will be a possibility that you will not have adequate blood pressure/blood volume.
what triggers ADH release?
high concentration of blood solutes such as salts cells and other blood matter.
what occurs when oxytocin is released?
- causes uterine contraction
- let down reflex, where nipples “stimulation” causes a lactating women feed her child.
- stimulates prostate gland to induce production of seimen.
what are the target regions of oxytocin?
men; prostate
women; mammary glands, uterus, nipples
what are the hormones produced by the thyroid gland
(thyroxine and triiodothyronine) they do the same thing just different structures and calcitonin
what do T3 and T4 control
metabolism specifically; -increases heart rate -increases cellular respiration -as a bi-product increased temp.
what does calcitonin control
it controls blood calcium concentrations
-it lowers blood calcium levels
what element is necessary for TH sythesis
Iodine
what hormone requires TH for full affect?
Growth Hormone
what is parathyroid?
it is the antithesis of calcitonin, it increases blood calcium levels
- it pulls calcium from the bones
- stimulates calcitriol production as well so the body will pull more calcium from the diet
what hormone is the most important in regulating blood calcium levels in an adult?
parathyroid hormone
what are the adrenal glands?
a pair of glands that lay on top of the kidney
what are the two parts of the adrenal glands?
ADRENAL CORTEX AND ADRENAL MEDULLA
what hormones does the adrenal cortex produce?
aldosterone
cortisol and androgens (converted to estrogen and testosterone)
what hormones does the adrenal medulla produce?
norepinephrine and epinephrine
what does aldosterone control
sodium potassium balances
what happens for aldosterone to be released?
low
- blood pressure
- blood volume
- increased potassium
What is aldosterone effect?
it reabsorbs sodium from the urine and adds it to the blood to increase blood pressure.
what does coritisol control?
energy metabolism of cells
-glucose and lipid utilization
why is maintaining glucose levels important?
the brain can only run on glucose
What do the non-neural cells utilize for metabolism when cortisol is released?
lipids
What causes cortisol to be released?
stress, also normal daily rhythms
what is the impact of cortisol?
depresses immune system
androgen
- adrenal cortex
- increases secondary sexual characteristics, women’s additional fat when compared to men, men’s additional muscle compared to women.
- poorly understood what it does in adults
Epinephrine, Norepinephrine
- made in the adrenal medulla
- widespread sympathetic response
- target body
- sympathetic increase
melatonine
- made inpineal glands
- sets circadian rhythms
- visual input regarding daylight
insulin
- made inpancreas
- stimulates glucose uptake by body cells
- target body cells
- rising blood glucose
what is diabetes?
diabetes is either that your pancreas has an inability to make insulin or your body is unresponsive to it.
glucogen
- pancreas
- stimulates glucose uptake by the body cells
- liver/muscle
- low blood glucose
calcitriol
- active form of vitamin D
- synthesised in skin with help of sunlight
- converted to final form in kidneys
- causes increased absorption of calcium from food
- always active in the small intestin if the products to make it are present
Atrial Natriuretic Peptide ANP
- made in heart
- decreases blood volume and blood pressure.
- kidney, hypothalamus and blood vessels
- works to reduce the volumes of water salt and lipids in the blood
- opposes aldosterone
leptin
- made in adipose tissue
- feeling of being full
- affects brain
- opposes insulin
what are the hormones important for growth
growth hormone, PTH, Calcitriol, insulin
what hormone is released in the alarm phase of stress ?
NOREPINEPHRINE
what is the effect of norepinephrine and cortisol?
-EPINEPHRINE ACTIVATES THE FIGHT OR FLIGHT
RESPONSE,
- CORTISOL PREPARES THE BODY FOR A LONG TERM STRESS BY CONSERVING GLUCOSE FOR THE BRAIN by switching non-neuronal cellular activity to lipids.
-CORTISOL HAS THE NEGATIVE SIDE EFFECTS OF CREATING SUGAR AND SODIUM IMBALANCES (DUE TO ALDOSTERONE RELEASE) AND DEPRESSING THE IMMUNE SYSTEM.