fibromyalgia

Question 1

what is it

Answer 1

chronic non-inflammatory, non-autoimmune diffuse central pain-processing syndrome

-not a primary disorder of muscle or connective tissue
-patients with FMS are more sensitive to other sensory modalities in addition to rpessure

Question 2

what are the cardinal manifestation

Answer 2

widespread pain
tenderness on exam
fatigue
depression
general somatic hyperawareness
cog problems
poor sleep

Question 3

what are the demographics

Answer 3

-young and middle aged women
->55 y/o
-hetergoenous disorder

can be associated with RA; secondary diagnosis

Question 4

what is the etiology

Answer 4

-unknown but evidence shows central pain processing disorder
-CSF, genetic, functional MRI studies
-biological changes in their brain

everything hurts

Question 5

talk about substance P

Answer 5

a part of pain processing
-concentration of substance P in cerebrospinal fluid is upregulated
-which speaks to the fact that there are neurochemical changes within the brain of people with this

-IL-8 upregulated too of pro inflammatory markers

Question 6

what is the medical tx

Answer 6

-not just meds
-exercise, sleep
-start low, go slow
-avoid opiods
-NSAIDs dont work
-change only one med at a time
-target central neurologic mechanisms of FMS

Question 7

talk about aerobic exercise

Answer 7

superior to resistance training in terms of pain benefit

Question 8

talk about resistance training

Answer 8

mod-intensity resistance training improves funcitonal statu,s tendermessm muscle strength

exercise can improve depressive symptoms

Question 9

talk about exercise in general

Answer 9

-flexbiilty may be helpful but aerobic and resistnace training more beneficial
-supervised group exercise can ehance adherence
-needs to be tailored to starting fitness level and symptom severity
-aquatic therapy can help wtih dpression/anxiety