Fertilization, Embryo Development and Embryo Signal Flashcards
What is the major sequence of events following deposition of spermatozoa into the Female tract?
- intermediate transport
- cervix
- uterus
- oviduct
- Fertilization
What occurs in the cervix (post sperm deposition)?
removal of non-motile sperm or sperm with abnormalities
What occurs in the uterus (post sperm deposition)?
capacitation initiated, phagocytosis
What occurs in the oviduct (post sperm deposition)?
capacitation completed and sperm become hyperactively motile
What occurs when there is fertilization?
acrosome reaction, spermatozoon penetrates oocyte and M + F pronuclei form
What occurs in the rapid transport phase?
muscularis contraction of the female tract, assist sperm into oviducts minutes after copulation
What occurs in the sustained transport phase?
Sperm are sent in slow and drop from reservoirs in the cervix for more uniform and sustained transport
Loss of sperm in the female reproductive tract is attributed to:
phagocytosis via neutrophils and retrograde transport
What is the function of sulfomicin in the cervix?
Increases viscosity in the apical zone of the cervical epithelium
What is the function of sialomicins in the cervix?
decreases viscosity int eh basal cervical crypts
What is sperm capacitation?
When the sperm loses surface molecules, for binding to the zona pellucida of the oocyte
What is the sperm protein that is the receptor for the zona pellucida?
ZP3
What is the acrosome reaction?
Its exocitosis of the sperm after binding ZP3 with receptor, that leads to F and M nuclei fusing.
What events must occur before the embryo can implant in the uterus?
Zona pellucida development and hatching, maternal recognition of pregnancy and formation of extraembryonic membranes
What is syngamy?
the fusion of M and F pronuclei
