Fentanyl drug sheet

Question 1

What is the presentation of fentanyl

Answer 1

100mcg in 2mL glass tubule
or
200mcg in cartridge

Question 2

What is the presentation of fentanyl

Answer 2

Synthetic opioid analgesic

Question 3

What are the CNS effects of fentanyl

Answer 3

1. CNS Depression - leading to analgesia
2. Respiratory depression - leading to apnoea
3. Dependence - addiction

Question 4

What are the CV effects of fentanyl

Answer 4

1. Decreases conduction velocity through the AV node

Question 5

How is it fentanyl metabolised

Answer 5

By the liver, excreted by kidneys

Question 6

what are the primary emergency indications for fentanyl

Answer 6

1. sedation to facilitate and maintain intubation
2. analgesia (pain relief)
   - History of hypersensitivity or allergy to morphine
   - Known renal impairment/failure
   - short duration of action required
   - Hypotension
   - Nausea/vomiting
   - severe headaches

Question 7

what are the contraindications for fentanyl

Answer 7

1. Hypersensitivity

2. late 2nd stage labour

Question 8

what are the precautions for fentanyl

Answer 8

1. Elderly/frail
2. Impaired hepatic function
3. Respiratory depression
4. Current asthma
5. Patients on monoamine oxidase inhibitors
6. Known addiction to opioids
7. Rhinitis, Rhinorrhea, facial trauma

Question 9

What are the side effects of fentanyl

Answer 9

1. Respiratory depression
2. apnoea
3. Rigidity of the diaphragm and intercostal muscles
4. Bradycardia

Question 10

Onset, peak and duration of fentanyl

Answer 10

IV:
Onset = immediate
Peak = less than 5 mins
duration = 30-60 mins

IN:
Peak = 2 minutes