Female oestrus cycle + imaging Flashcards
When are oocytes produced
during embryological development
When is puberty in the bitch
80% of her breeds average adult bodyweight
mean age 9 months(6-14 months)
When is puberty in small-medium breeds in the bitch
6-8 months
When is puberty in Giant breeds in the bitch
Until 18-20 months or even as late as 24 or 30m
When is puberty in the queen
80% and between 4-12 months of age
What can affect when puberty occurs in the queen
Photoperiod- time of year at their bitch
social environment and body condition and breed
When is puberty in the queen for oriental breeeds
Early (4months)
When is puberty in the queen for longhaired and manx breeds
later (11-21 months)
What is the oestrus cycle
Rhythmic phenomenon involving regular but limited periods off sexual receptivity(oestrus) that occur at intervals characteristic of a species
Interval between one ovulation and another
Classifications of oestrus cycle
Mono-oestrous
Polyoestrous
Seasonal
non seasonal
What is Mono-oetrous
Animals experience oestrus once each year
What is polyoestrous
Animals including most domestic species have more than one period of oestrus in a year
What are the 2 phases of oestrus cycle
Follicular phase
Luteal phase
What is the follicular phase
Characterised by high blood oestrogen levels
What are the 2 phases of the follicular phase
Pro-oestrus and oestrus
What is luteal phase
Period of preparation for pregnancy
What are the 2 divisions of luteal phase
Metestrus and dioestrus
What is anoestrus
Period of sexual inactivity
What is a period of sexual inactivity called
Anoestrus
What are the 2 main parts of the ovary
Cortex and medulla
What is the ovary cortex and what does it contain
Outer layer
Contains follicles of varying sizes and stages of maturation
What is the ovary medulla and what does it contain
Inner layer
composed of loose connective tissue with blood vessels, lymphatic vessels and nerves
When does oogenesis begin and restart
Begins in first half of foetal development and continues at puberty and stops in childhood
What happens in the fetal period in oogenesis
Undifferentiated germ cells in genital ridge divide by mitosis giving rise to oogonia which migrate to the ovaries
Then oogonia enter meiosis 1 becoming primary oocytes then is dormant until resumes at ovulation
What are the stages of oogenesis
Oogonium to primary oocyte then to primary oocyte in meiosis then dormancy then primary oocyte meiosis to a secondary oocyte with first polar body, then secondary oocyte with second polar body
What are primordial follicles
House oocytes from primary oocyte in fetal period
Describe folliculogenesis
Primordial follicle in fetal period then dormancy until puberty then primary follicle and secondary follicle then a mature(graafian) follicle
Stages of folliculogenesis
Primordial follicle, dormancy, secondary follicle, mature(graafian) follicle
What does primordial follicle house
Primary oocyte in fetal period
What does a primary follicle house
Primary oocyte in puberty
What does a secondary follicle house
Primary oocyte in puberty
What does a mature(graafian) follicle house
Secondary oocyte in puberty
What happens to the polar body from the oocyte
disintegrates
What happens if secondary oocyte is fertilized
Completes meiosis 2 yielding a mature ovum
What type of oocyte is ovulated in the queen
Secondary oocytes are ovulated and immediately fertilisabel
What type of oocytes is ovulated in the bitch
Before completion of meiosis 1 so Primary oocyte so cannot be fertilized immediately and has to mature which takes about 2 days
Name hormones involved in female reproductive system
Gonadotrophin-releasing hormone (GNRH)
Follicle-stimulating hormone (FSH)
Luteinizing hormone (LH)
Oestrogen (E2)
Progesterone (P4)
Inhibin
Name Hormonal control for Early Follicular phase
LH stimulates production of E2 precursors in thecal cells of follicle- (Androgens)
FSH stimulates conversion of androgen into E2 in granulosa cells
E2 stimulates follicular development of the dominant follicles
E2 exerts negative feedback on hypothalamus and AP (inhibts GNRH, LH, FSH) - hormonal regulation
Describe hormonal control for Late Follicular phase
E2 levels increase rapidly to exceed a threshold
Changes negative feedback on hypothalamus to a positive feedback on surge centre
Large quantities of GnRH causes LH surge from AP
Due to inhibin the increase of FSH is smaller than LH peak
LH surge induces ovulation
Hormonal control for luteal phase
The cavity and the fribrin clot from ruptured folicle form framework for luteal cells to develop and form corpus haemorrhagicm
Blood vessels form theca externa invade CH and become vascularised to form corpus luteum
Maintence of CL is from LH
CL is responsible for production of Progesterone
P4 stimulates closure of cervix and endometrial thickening and mammary glands
P4 inhibits GnRH, FSH and LH
Name the stages of Oestrus cycle in Bitch and length
Pro-Oestrus (7-10 days)
Oestrus(7-10 days)
Dioestrus(2 months)
Anoestrus(4.5 months)
What type of breeding pattern is in the btich
Non-seasonal mono-oestrus cycle followed by obligatory anoestrus period
Describe simple pro-oestrus in bitch
Attracts males but not mates
Describe simple oestrus in bitch
accepts mate
Describe simple dioestrus in bitch
Whether pregnant or nonpregnant
Describe simple anoestrus in bitch
ovarian inactivity
Length of oestrus cycle in btich
approx 6-7 months and range is 5-12 months
When is Day 0 for oestrus cycle bitch
LH surge occurs in late pro-oestrus/ early oestrus
What kind of ovulator is the bitch
Spontaneous ovulator- ovulation occurs 48-72 hourspost LH surge
What can be used to detect ovulation in just the bitch
Progesterone concentratiosn are detectabke in circulation just before ovulation
Signs of oestrus in the bitch
vulvar discharge
vulvar swelling 2-3 times the size
Monitoring scientific techniques for oestrus in the bitch
exfoliative vaginal cytology
vaginoscopy
hormonal tests- progesterone and LH
What type of breeding pattern is the queen
Seasonal polyoestrus breeeding pattern
Periods of repeated oestrus activity at intervals of 14-21 days initiated by increasing day length
Followed by seasonal period of anoestrus 3-4months in winter
Describe the polyoestrus oestrus cycle in the queen
Periods of repeated oestrus activity at intervals of 14-21 days initiated by increasing day length
Followed by seasonal period of anoestrus 3-4months in winter
females indoors and not exposed to changing photoperiod can cycle practically throughout the year
What type of ovulator is the queen
Induced ovulator
ovulation triggered by coitus or mechanical stimulation of the vaginal wall
rarely ovulation without mating (spontaneous) could be grooming, age of presence of male
Name the stages of the oestrus cycle in the queen
Interoestrus (8-15 days)
Pro-oetrus (0-1 days)
Oestrus(2-6days)
Luteal phase Non pregnant(25-45 days)
pregnant (65days)
Absence of mating there is not luteal phase so followed by interoestrus
Uses of diagnostic imaging
disease diagnosis or establish a database of normal anatomy as a reference
Most common diagnostic imaging for urogenital system
Radiography
ultrasonography
CT, MRI
renal scinitgraphy
When do foetal skeletons ossify in dog and cat
dog-42-45 days
cat-35-39 days
of gestation
What is size of kidneys (radiology) compared to L2 (lumbar veterbrate 2)
Dog- 2.5-3.5 times
cat- 1.9-2.6 times the length is neutered and 2.1-3.2 if entire
Position of kidneys (radiology) in the dog
right- T12-L1 veterbrate
left- L1-L3
Position of kidneys (radiology) in the cat
L1-L4 with right kidney either more cranial or same level as left
Why are plain radiographs limited in evaluating urinary bladder
as soft tissue and fluid are the same radiographic opacity making the bladder wall indistinguishable from fluid within the lumen
Is the urethra accessible using ultrasound or plain radiography
no so have the use a contrast media with radiography
GnRH activity
release FSH and LH
FSH activity
Stimulate follicular development
conversion of androgens to oeestrogen
LH activity
Productions of oestrogen precursors (androgens)
ovulation following LH surge then maintenance of corpus luteum
Oestrogen activity
Stimulate LH surge, negative feedback on FSH production and endometrial thickening, mammary glands and brain behavioural centres
Progesterone secreted by
corpus luteum
Progesterone activity
Closure of the cervix and maintenance of pregnancy, negative feedback on production of FSH and LH via GnRH inhibition
Inhibin acitivty
Inhibits FSH production