Feline Flashcards
low potassium
septic abdomen
total T4
see hyperthyroidism power sheet
acetylcysteine and S-adenosylmethionine
systolic blood pressure, serum chemistry panel and thyroid hormone levels
which is not a common sequela of hypertrophic cardiomyopathy in cats
* right heat failure
* systolic anterior motion of the mitral vale
* thromboembolism
* left heart failure
right heart failure
2 yr old, normal activity and appetite. non painful. How to treat?
* antibiotics
* radiation
* spay
* bilateral radical mastectomy followed by chemo
* bilateral radical mastectomy without chemo
spay
efferent to left eye
- no matter which eye light is shined in, there is no motor (or efferent) response in the left eye
pyelonephritis
- pollakiuria and dysuria are lower urinary tract signs that are not consistent with pyelonephrititis alone. They would be systemically sick: fever, anorexia, depression
If T. blagburni is not identified and treated properally, it will cause small bowel diarrhea indefinetly
see small animal parasites: protozoa
white cats with blue eyes are commonly born with what defect?
deafness
horner’s syndrome
MRI
Collagenolytic granuloma
mirtazapine as an appetite stimulant
cat with chronic cough
capillaria
IV calcium gluconate
see feline obstruction power page
herpesvirus infection
see herpes ocular video
fluconazole
- cryptococcus- encapsulated fungus
- treat with anti-fungals such as fluconazole or itraconazole
clindamycin for toxoplasma, fenbendazole for internal parasities such as hookworms, roundworms and giardia. Chlorambucil is a chemo drug for lymphoma
external beam radiation therapy for acromegaly
anemia, peripheral eosinophilia, tapeworm infection
see flea allergy power page
good, mean survival is greater than 2 years
bovine
supportive care and fluid therapy plus treatment with ampicillin, metro and ursodeoxycholic acid
dilated cardiomyopathy
epi will prolong the duration of lidocaine’s effects
what is the causative agent for feline infectious anemia?
mycoplasma heamofelis
has ear mites amd clotrimazole(antifungal) does not work for those
- the dog had yeasty ears not mites
cat with hyperthyroidism with mild clinical signs and normal serum total T4. Which diagnostic test would you run next?
free T4 by equilibrium dialysis
anterior uveitis
anterior uveitis video
hypoglycemia post surgery, which needs close BG monitoring
toxoplasma
- toxoplasma gondii tachyzoites multiplying within macrophages and neutrophils
vaginal cytology showing mostly cornified epithelial cells
cheyletiella
diazepam
biopsy of the pad lesions
FIP
see FIP powerpage
acidifying diet
see urolithiasis/stones power page
FIC
- lesions will most likely spontaneously regress
an ionized calcium level
fleas
calicivirus
electrocardiogram, retrograde urethrogram, coagulation panel
chemistry panel
see hyperthyroidism power page
place a penrose drain for 4 days
a large % of cats are seropositive for Toxoplasma gondii, but are not necessarily shedding oocysts
steroids
see chronic renal insufficiency power page
measure serum fTLI concentration
stargazer lilly
on the antimesenteric border
enema, laxatives, cisapride, fair prognosis
1-3 weeks from the end of the current estrus
metabolic acidosis, electroylte disturbances, hyperosmolality
- DKA
gastric lavage, activated charcoal, vit K daily for 30 days
see rodenticide toxicity power page
retrobulbar abscess
atenolol
draw blood for a fructosamine level
see diabetes mellitus
intoxication with cholecalciferol based rodenticide (Dcon)
see hypercalcemia power page
horners
disruption of the sympathetic trunk traveling along the neck.
feline panleukopenia virus
esophageal stricture
see hyperthroidism power page
portal systemic shunt
listen to portosystemic shunt video
fecal oral transmission
see feline infectious peritonitis power sheet
when light is directed into the abnormal eye, the pupil in the normal eye stays dilated
If T. blagburni is not identified and treated properly, it will cause small bowel diarrhea indefinitely
naloxone
progesterone
euthanize and test
coccidia are incredibly environmentally resistant and difficult to disinfect, coccidia are also species-sepcific so the baby is not at risk but the other cat could become infected
see parasite-protozoa page
treat with: Sulfadimethoxine
saddle thrombus
Diazepam
the other side may start to show the same signs within a few weeks to months.
psychogenic alopecia
Itraconazole
power lecture- cryptococcus
acid fast stain
cuterebra
the effusion is strongly suggestive of FIP
see FIP power page
british shorthair, devon rex
well circumscribed
expiratory push
administer mirtazapine as an appetite stimulant
atenolol
atelectasis
B. henselae
2
yohimbine (antagonil- alpha 2 antagonist)
xylazine is what type of med? is it reversible?
alpha 2 agonist
yohimbine- alpha 2 antagonist
opioid reversal
naloxone
midazolam is a — and can be reversed with —
benzo
flumazenil
crystalloids and insulin
protein losing nephropathy
what kind of drug is enalapril
ACE inhibitor
* vasodilator, antihypertensive, heart failure treatment
* prevents angiotensin 1 to angiotensin 2, this will reduce aldosterone and cause diuresis
* dilatory effects on efferent arterioles of glomeruli help to reduce protein losing nephropathies
ioized calcium
vaginal cytology showing cornified epithelial cells
if an LH level is —, an ovarian remant is likely. If it is — it does not rule it out
low
high
palpable nodule in the area of the thyroid gland
historical signs of hyperthyroid in a cat
weight loss, polyphagia, vomiting, hyperactivity.
physical exam sign of cat with hyperthyroidism
- thyroid nodule (or “slip”)
- tachycardia
- heart murmur or gallop
- vomiting
- weight loss with polyphagia
- hyperactivity
how to diagnosis hyperthyroidism in cat
- serum total T4 levels (> 4.0)
- elevated ALT, ALP, AST
- erythrocytosis
- HTN
how to treat hyperthyroidism in cats
methimazole (tapazole)
surgery
radioactive I-131
if total T4 < 4 in cat what to do if you suspect hyperthyroidism
free T4
TRH response testing
T3 supression test
— used to treat hyperthyroidism in cats can cause facial excoriations
methimazole
bathe, IV fluids, methocarbamol
how to treat pyrethrin toxicity in cats
- caused by some flea meds- can cause hypersalivation and tremoring
- wash
- methocarbamol- muscle relaxant for seizures
calcium gluconate
giardia- fenbendazole or metro
FIV- saliva and bites
* fighting disease
no treatment
* coccidian- not parasitic
* 2ndary to coprophagy
* eimeria: 4 sporocysts- parasitic in reptiles, birds, herbivores
isospora is an infectious — in dogs and cats that can be treated with —
coccidian
sulfadimethoxine (albon)
anterior uveitis
diabetes can cause cataracts in
dogs
* uncommon in cats
cisplatin
cisplatin can cause — in cats
fatal pulmonary edema
* cis- plat splats cats
flurorouracil can cause — in cats
neurotoxicity
- contraindicated
tritrichomonas foetus, ronidazole
* flagellated parasite that can cause unresponsive diarrhea
* difficult to diagnose
paragonimus kellicotti is a —, treated with —
lung fluke
eggs passed in feces
fenbendazole and praziquantal
taenia is a — that is treated with —
tapeworm
praziquantel
how to treat cryptosporidum
clindamycin
azithromycin
tylosin
prolongs the duration of the effects
* causes local vasoconstriction, preventing rapid systemic absorption
subtotal colectomy
superficial skin scape
difference between demodex in a cat vs a dog
demodex gatoi- itchy, superficial
demodex cati- contagious, deep
demodex canis- deep
surgery after stabilizing
blood pressure, chemistry and thyroid panel
chlamydophila felis
herpes or chlamydophila felis will cause systemic disease
herpes- ocular, dendritic ulcers with systemic disease
chlamydophila- severe chemosis
upper GI obstruction
addisons will cause — potassium
high
GI obstruction will cause — on bloodwork
hypochloremic metabolic alkalosis
(chloride low)
(TCO2 high)
urethral obstruction causes — potassium
high
IFA positive= truly infected
efferent to the left eye
blood pressure
intramedullary pin
monitor and spontaneously regression
primary met acidosis with compensatory resp alkalosis
- ph tells you acidemic
- negative base excess or low HCO3 tells you met acidosis
- low PaCO2 test you resp alkalosis (hyperventilation)
respiratory acidosis is seen by —
high pCO2
respiratory alkalosis is
low pCO2 (hyperventilation)
high bicarb is
metabolic alkalosis
* normal anion gap (Na+K)-(HCO3+Cl)
* high bicarb
* Cl much lower than Na
* loss of HCl from vomiting
* ileus/ internal vomiting in large animal
* low K can cause paradoxic aciduria (high H)
* pt dehydrated tries to absorb NaCl, no Cl so it reabsorbs Bicarb instead= high bicarb in blood
* low K in blood from pt not eating
— pCO2 is respiratory acidosis
high
low bicarb can mean
metabolic acidosis
Titrational met acidosis
* normal AG, low bicarb, normal Cl
* KLUE=
* ketones- in urine= DKA
* lactate- dehydrated (high albumin, NaCl, PCV, BUN, Creat), low PCV= anemia= low O2
* uremic acid- azotemia
* ethelyn glycol- AKI= anuria and high K (monohydrate crystals)
* loss of bicarb
Loss metabolic acidosis
* normal AG, low bicarb, high Cl» Na
* renal loss- AKI, azotemia=casts, low NaCl, normal BG, + glucose in urine
* choke- LA
* GI disease- diarrhea
—- HCO3 is metabolic alkalosis
high
explain paradoxical aciduria
metabolic alkalosis (high bicarb) with acidic urine
- hypovolemia- body tries to reabsorb Na to maintain ECF and plasma volume, Cl follows Na and triggers RAAS
- GI obstruction/vomiting: loss or seg of HCl. Metabolic alkosis from drop in H+, low Cl- Cl not reabsorbed with Na, Bicarb replaces Cl and is reabsorbed with Na= acidifies urine
- RAAS (aldosterone): keep Na/excrete potassium, low K: if no K available to exchange for Na, then H excreted with Na is reabsorbes= acidifies urine
aluminum hydroxide (phosphorus binder/antiacid)
SCC-poor prognosis
acetaminophen: tylenol
hyperadrenocorticism
cats with DKA can also have —
while dogs with DKA can also have —
- Cats: hyperthyroidism, cardiac disease
- dogs: hyperadrenocorticism
- both: pancreatitis and bacterial infections
upper GI obstruction
eat normal diet
what can cause pancreatitis in dogs
- Fat – obesity, fatty meals, hyperlipidemia
- Systemic inflammation, trauma, ischemia
- Endocrine diseases – hyperadrenocorticism, diabetes mellitus
- Drugs – azathioprine, l-asparaginase, tetracycline
- In cats, the causes of pancreatitis are not as well understood
what drugs can cause pancreatitis in dog
Fat – obesity, fatty meals, hyperlipidemia
● Systemic inflammation, trauma, ischemia
● Endocrine diseases – hyperadrenocorticism, diabetes mellitus
● Drugs – azathioprine, l-asparaginase, tetracycline
● In cats, the causes of pancreatitis are not as well understood
Clinical signs of pancreatitis in dogs
- Mainly GI signs: vomiting, diarrhea, anorexia, cranial abdominal pain. A dog that hunches in a “praying posture” is a diagnostic clue for pancreatitis.
- Severe necrotizing pancreatitis can cause hypovolemia, fever, tachycardia, jaundice, and the systemic inflammatory response syndrome (SIRS).
clinical signs of pancreatitis in cats
Tend to have non-specific lethargy and anorexia and may or may not have any of the other GI signs like dogs: vomiting, diarrhea, anorexia, cranial abdominal pain
how to treat dogs with acute pancreatitis
- Treatment is largely supportive and can be controversial, but it is generally agreed that delaying
feeding, post-duodenal feeding by tube, and/or feeding a NO fat diet is helpful
● Hospitalization and aggressive intravenous fluid therapy if indicated
● H2 blockers (i.e. Ranitidine) and anti-emetics
● Analgesics
● Antibiotics are only indicated if pancreatic necrosis or sepsis is suspected
● Plasma or heparin administration may be indicated in severe cases
Treatment for chronic pancreatitis in dogs is to maintain a low-fat and highly digestible diet and to monitor closely for signs that require intervention
what type of dogs get exocrine pancreatic insufficiency
German Shepherds, Collies and English Setters
Chronic — is the most common cause of EPI in cats.
pancreatitis
— is the most common cause of EPI in the dog
Pancreatic acinar atrophy
clinical signs of EPI
Small bowel diarrhea with voluminous, yellowish or gray feces, polyphagia, pica, weight loss, and dermatological problems
how to treat EPI
- give enzymes: powered pancreatic extracts
- Parenteral cobalamin, vitamin K and oral vitamin E supplementation
- Highly digestible, low-fiber diet
difference in feeding of a cat or dog with pancreatitis
cat: continue normal feeding
dog: hold food or give NO fat diet
which demodex in cats is itchy and contagious
demodex gatoi: superficial
demodex cati: deep
thoracocentesis
osteosarcomas are worse in dogs or cats?
dogs
in cats, they are slow to met and amputation can be curative
hyperkalemia
hyperkalemia changes the ability of the cell wall to repolarize, resulting in — cell membrane potential
decreased
this causes a decrease in myocardial excitavility and conduction = bradycardia
admit patient for fluid therapy and supportive care
pleural fluid triglyceride > serum triglyceride
pleural fluid glucose < serum glucose
infectious
not itchy from cat
ileocolic artery
no treatment at this time
have housemate empty box, takes 1-3 days to sporulate
humulin-R (regular insulin)
what insulin for cats that have been in DKA in the past
glargine (lantus)
PZI
- longer acting insulin
left shift on bloodwork would indicate
immature neutrophils
and high neutrophil count
primary hyperparathyroidisim and surgery
cryptococcosis
what meds can cause fatal dysbiosis in GP rabbits and degu
beta lactams: ampicillin
lincomycin
clindamycin
erythromycin
steroids
diazepam rectally
herpes and chlamydophila: topical tetracycline
serum T4: hyperthyroid
I-131
negri bodies may be seen with
rabies
how to treat giardia
fenbendazole or metronidazole
small yeast with large capsule in a CSF tap may be
cryptococcus
latex agglutination titer of — on CSF and — in serum indicated cryptococcus infection
1:100
1:10,000
hyperkalemia
signs of DM in cats vs dogs
plantigrade stance in cats
cataracts in dogs
both: PU/PD, polyphagia, weight loss, recurrent infections
what type of diet for a diabectic dog
Diet: A consistent diet is critical, the type of food, amount, and time of feeding.
i. High fiber, moderately fat-restricted diets are recommended.
ii. High protein and low carbohydrate diets for cats may be beneficial.
how to treat DKA
- Aggressive IV Fluids – 0.9% saline with potassium and phosphate supplementation as needed.
- Regular insulin: Regular insulin is the fast-acting insulin of choice for severe DKA. It can be given intermittently (q 6-8 hrs) or by continuous IV infusion.
- With either, frequent blood glucose monitoring and insulin dose adjustment is necessary to achieve gradual decline in blood glucose level.
- Bicarbonate Therapy - if metabolic acidosis is severe and/or not improving with IV fluids.
- Identify and address any concurrent infections or diseases.
hyperthyroid
what are the round cell tumors
lymphoma
mast cell tumor
plasma cell tumor
histiocytoma
transmissible venereal tumor
+/- melanoma
methimazole (tapazole)
histopath of FIP will show
- disseminated pyoganulomatous and fibronecrotic reactions around small veins
- gold standard for diagnosis
cat
toxoplasma
cytauxzoon felis, tick prevention and indoor only
Cytauxzoon felis vs mycoplasma haemofelis on a slide
HCM in cats causes — heart failure
left
left ventricle becomes stiffer and blood backs up into the pulmonary vessels = left sided heart failure
— is an essential amino acid in cats that is used to make ornithine, which binds to ammoniona that is formed from the breakdown of proteins
arginine
— can be seen in cats on raw diet which can cause neurologic symptoms
thiamin
* thiaminase depletes the body of thiamin
low — results in buildup of ammonia and signs are similar to hepatic encephalopathy
arginine
low — in cats causes weight loss, anorexia, poor hair coat, ulcerations and erythema of the tongue and palate and diarrhea
niacin
low — can cause inappetance, lethargy and failure to thrive
cobalamin
in cats low — can cause feline central retinal degeneration and —
taurine (elliptical area of tapetal hyperreflectivity starting in the area centralis dorsolateral to the opic disk that progresses to a horizontal band and can involve the entire fundus)
cardiomyopathy
chemistry for baseline renal functions
hyperthyroidism can cause — renal perfusion and — GFR
increased and increased
feline lungworm — is treated with —-
Aelurostrongylus abstrusus.
ivermectin and fenbendazole
supportive care with fluids, ampicillin, metro and ursodeoxycholic acid
medetomidine
— are reversals for alpha 2 agonists
yohimbine
atipamezole (antisedan)
itrazonazole
— is a drug that can cause pemphigus foliaceus in cats
itraconazole
calici, clindamycin and sucralfate
— is a common virus that can cause upper respiratory symptoms as well as oral ulcers and stomatitis in cats
calicivirus
- treat with clindamycin, doxy, clavamox (amoxicillin clavulanic acis), sucralfate to help ulcers
histopath of cat gut with lymphocytic plasmacytic enteritis is consistent with
IBD
- treat underlying cause, control inflammation and control bacteria
- steroids and hypoallergenic diet
xylazine
low paCO2 is
respiratory alkalosis or hyperventilation
more negative base excess means
metabolic acidosis
low pH and low bicarb can also mean this
contagious, itchy and lives superficial
— demodex lives superfically and is contagious and itchy
demodex gatoi
- demodex cati- deep
in utero or perinatal infection of kittens with — can cause cerebral hypoplasia, leading to inability to —
feline panleukopenia
- inability to regulate and measure motor function, ataxia, dysmetria, vestibular signs, delayed postural reactions
stargazer lily
lyme sulfur dip
— causes ringworm in cats
dermatophyte microsporum canis
- treat with lyme sulfur dips
prognosis of cat with mammary mass vs dog
cat: almost all met and are malignant
dogs: 50/50
both cats and dogs are at increased risk of mammary masses if they are spayed after 1 or more heat cycles
linear foreign body
rodenticide
PTH – Causes — Ca and P mobilization from bone and promotes phosphate — and calcium — by the kidneys
increased
excretion
retention
(overall should cause increased Ca and decreased P).
— overall should cause increased Ca and decreased P.
PTH – Causes increased Ca and P mobilization from bone and promotes phosphate excretion and calcium retention by the kidneys (overall should cause increased Ca and decreased P).
Calcitriol – —Ca absorption from intestines and results in — P as well.
Increases
Increased
— Reduces calcium levels by inhibition of osteoclastic bone resorption.
Calcitonin
clinical signs of hypercalcemia
- Polydipsia, polyuria
- Anorexia
- Depression, weakness
- Vomiting
- Constipation
- Arrhythmias
- Seizures, muscle tremors
causes of hypercalcemia
GOSH DARN IT
○ G – Granulomatous disease, growing young dogs
○ O – Osteolytic disease (osteomyelitis, neoplasia)
○ S – Spurious (lipemic or post-prandial blood samples, lab error, hemolysis)
○ H – Hyperparathyroidism (primary)
○ D – Drugs (thiazides, calcium containing phosphate binders)
○ A – Addison’s disease (hypoadrenocorticism)
○ R – Renal failure (acute or chronic)
○ N – Nutritional (Hypervitaminosis D- from drugs, cholecalciferol rodenticide, or poisonous
plants, hypervitaminosis A, or excess Ca)
○ I – Idiopathic (mainly cats)
○ T – Tumors
■ Humoral hypercalcemia of malignancy: Most commonly lymphoma, apocrine gland anal sac adenocarcinoma
■ Bone osteolysis: Most commonly multiple myeloma. Also lymphoma or bony neoplasia
ethylene glycol can cause — calcium by
low
chelation of calcium by metabolites of ethylene glycol such as oxalate
fleet enemas are — phosphorus and — calcium
fleet enemas are high in phosphorus and lead to a decrease in serum calcium due to law of mass action
how does rat poision affect calcium levels
cholecalciferol based rodenticides
* cholecalciferol gets converted to active vit D to cause increased bone resoprtion of calcium and gut absorption of calcium leading to a sometimes fatal hypercalcemia
dilated cardiomyopathy
dexmedetomidine is a —- drug
alpha 2 agonist drug
normal to enlarged adrenal glands
skin fragility sundrome in cats is associated with — regulated DM due to —
poorlu
cushings, which can cause insulin resistance
cats with cushings, 80% will have a — tumor and 20% will have a — tumor
pituitary
adrenal
with a pituitary tumor causing cushings you expect the adrenal glands to be —
enlarged
* excessive ACTH secreted from the pituitary gland produces as high amount of cortisol and adrenal hypertrophy
SCC
—- is the most common oral tumor in a cat, — is the most common oral tumor in dogs
cats: SCC, fibrosarcoma
Dogs: melanoma, SCC, fibrosarcoma, epulides
environmentally resistant but species specific
euthyroid sick syndrome occurs when concurrent illness causes T4 to —
decrease from being high down into normal range or from the normal range to below normal
place a chest tube to drain and lavage chest and antibiotics
spay and remove external
renal toxicity
sterile hemorrhagic cystitis is caused by what drug in dogs, but not in cats
cyclophosphamide
what cancer drug causes neurotoxicity and should NOT be used in cats
5- fluorouracil
protein losing nephropathy
enalapril causes vaso—
dilator
- ACE inhibitor that causes vasodilation, anti HTN, and heart failure treatment
- prevents conversion of angiotensin 1 to 2, thus reducing aldosterone and causing diuresis
- dilatory effects on the efferent arteriols of the glomeruli help with protein losing nephropathies
right sided heart failure
fleas cause loss of hair where for a cat vs dog
dogs: caudal dorsal: base of tail, ventral abdomen, hind legs
Cats: neck and face, miliary dermatitis, eosinophilic gramuloma complex, can be same as dog, symmetrical alopecia of the dorsal lateral trunk
which flea medication is toxic to cats
permethrin (vectra, K9 advantix)
physiological leukogram
A
conjunctivitis
- ptosis: upper eyelid drooping
- miosis: constricted pupil
constricted pupil medical term
miosis
dilated pupil medical condition
mydriasis
alprazolam is what kind of med
xanax
benzo derivative ( antidepressent not SSRI)
clompiramine is what kind of drug
tricyclic antidepressent
inhibits seortonin norepinephrine re-uptake but they are not selective serotonin re-uptake inhibitors (NOT SSRI- like fluoxetine(prozac))
what is the average duration of estrus in a cow
8-18 hours
what is the most common locations for primary osteosarcoma in large breed dogs
(toward the knee)- distal femur and proximal tibia
(away from the elbow)- proximal humerus and distal radius
the most common reasons that a cat with lymphoma develops dyspnea is
intrathroacic mass
* can either cause pleural effusion reducing the volume of the pulmonary parenchyma or the can compress the lungs and airways
can you use ketoconazole in cats
NO
hepatotoxic and causes vomiting and diarrhea in cats
spay
what kind of drug atenolol
beta blocker
decreases contracility and heart rate thus allowing for better chamber filling before contraction
cat scratch disease is caused by
bartonella henselae
* fleas carry the bacteria
— is a fungus found in the soil that causes rose growers disease
sporothrix
how is toxoplasmosis transmitted
ingestion of oocytes in raw meat
ringworm
dermatophyte fungus
treat with lyme sulfur dip in cats
what chemo drug causes fatal pulmonary edema in cats
cisplatin
” cis-plat splats cats”
which chemo drug is neurotoxic in cat
5-fluoruracil
theophylline causes
bronchodilation
— nystagmus is only seen with central vestibular disease
vertical
atipamezole (antisedan)- alpha 2 antagonist
2
gestational period for a cat
63 days
* fetal skeletons xray by 42 days
* US by 13 days
herpes can cause what eye things in cats
conjunctivitis
corneal sequestrum
corneal ulcers
eosinophilic keratitis
thromus from cats with HCM comes from —
dilated left atrium
* left ventricle is hypertrophied
how to treat chlamydophila felis
topical tetracycline QID for one week post resolution of clinical signs
milbemycin is what med
interceptor- hookworm, roundworm, whipworms
blood transfusions are indicated when PCV is less than —
20
how does rat position Dcon work
brodifacoum
* inhibits epoxide reductase resulting in a loss of active Vit K, (factors 2,7,9,10)
* clinical signs at 3-5 years and bleeding
* oral Vit K for 30 days
* PT checked 48 hours after last dose of Vit K
which coag factors for vit K dependent
2,7,9,10
Cholecalciferol rodenticides results in what bloodwork findings
hyperphosphatemia (12 hours post)
severe hypercalcemia (24 hours post)
azotemia (36-48 hrs)
canine insulin is similar to
porcine insulin
major causes of non-cardiogenic pulmonary edema
vasculitis, liver disease, seizures, toxins, venom, DIC, trauma, sepsis, electrocution
how to treat hyperthyroidism in cats
surgery
radioactive iodine treatment
anti-thyroid drugs (methimazole)
low iodine diets
what is acromegaly
excessive growth hormone for the pars distalis from a tumor
* causes defect in insulin receptors on target cells causing insulin resistant DM
* symptoms: enlarged head, paws, abdominal organs. weight gain from anabolic effects of growth hormones
* treat with: external beam raditation
what is prognathism
big lower jaw
how to treat eat mites in kitten
in dry form FIP globulins are —
high
* mature neutrophilia, lymphopenia. NR anemia
histopath of Dry form FIP is
perivascular pyogranulomatous inflammation
how to treat “white rice” in cat
tapeworms: taenia taeniaeformis or Dipylidium caninum
praziquantal (droncit/drontal)
how does amlodipine work
calcium channel blocker- prevents calcium influx into vascular smooth muscle = causes vasodilation
when do horse teeth eruprt
what is the carrier of mycobacterium leprae in the US
armadillo
how to treat a coughing cat + for heartworm
prednisolone and heartgard
- cats treat inflammation from infection. heartgard to kill adults
ketocanozole does what to cats
hepatotoxic and causes vomiting and diarrhea
* ketoconazole is an antifungal
histoplasmosis is found?
MIDWEST and mississippi river
blastomycosis is found
coccidiodomycosis is found ?
how to treat histoplasmosis
itraconazole
Midwest and mississippi river
— is the hunting dog fungi
- blastomycosis- very thick walled budding yeast
- ohio river valley and eats of the mississippi river
- vegetation, pigeons and bats
- snowstorm chest rads
- itraconazole
cryptococcus treatment
amphotericin B +/- fluconazole
* pacific northwest
* “roman nose” cats: pigeoon poop and soil
— causes roman nose cats
- Cryptococcus neoformans and Cryptococcus gattii
- fungi- pacific northwest
- pigeon poop and soil
- amphotericin B +/- fluconazole
— fungi is found in the southwest after heavy rainstorm or dust storm
coccidioidomycosis- coccidioides immitis- fungi
* ketoconazole for 3 months, Itraconazole for 3 months
— is used to treat urinary incontinence from urethral hypotonicity most often in dogs
phenylpropanolamine
proin: sympathomimetic: alpha and some beta: causes release of Norepi and inhibition of reuptake
* increases urethral sphincter tone and produces closure of the bladder neck
cat with cough
— deficiency can cause feline central retinal degeneration (FCRD)
taurine
also causes cadiomyopathy
echo and diuretics
what does methocarbamol do
skeletal muscle relaxant
* used for pyrethroid, struchnine, amphetamine toxicities
where to place a G tube
left paracostal regio 2-3 cm caudal and parallel to the last rib
skin fragility syndrome in cats is 2ndary to poorly controlled DM due to —
cushings
80% of cats have pituitary tumor leading to enlarged adrenal glands
in cats with cushings what is the recommended test
LDDS:
because 80% of cats with cushings have a pituitary tumor
what liver values are elevated with hepatic lipidosis vs cholangiohepatitis
- lipidosis: high ALP, ALT, bili but normal GGT
- chol: high GGT
aluminum hydroxide is a —
phosphorous binding agent
metabolic acidosis (low pH, more negative base excess and low HCO3)
compensatory resp alkalosis: low paCO2: hyperventilation
compare mammary masses in dogs to cats
cats: most malignant and will met
dogs: 50/50 are malignant and of those 50% will met
thiopental is what kind of drug
barbiturate
steatorrhea
fatty stool
normal bloodwork findings for hyperthyroid cat
what can be seen on a cat with a physiological leukogram
- mild neutrophilia
- normal to increased lymphs
- no monocytosis
what call types are found on liver biopsy of cat with lymphocytic portal hepatitis vs cholangiohepatitis
lymph: lymph and plasma cells
choli: neutrophils
what is the rivalta’s test
adrenergic neurons release
norepi
how does norepi effect alpha 1 receptors
causes increase in Calcium= increase in contraction
* smooth muscle vasoconstriction= ↑SVR= ↑ BP
* internal urethral sphincter= increase contraction= inhibits urination
* pupil muscle to contract= dilates pupil
adrenergic neurons release NE
how does NE effect alpha 2 receptors
causes decrease in cAMP
causes increased potassium efflux, can cause hyperpolarization of cells= inhibits secretions
* receptor on presynaptic nerve terminal that bind to NE and inhibit release of more NE
* pancreas: beta cells make insulin: alpha 2 will inhibit secretion of insulin= ↑BG
aphla 2 drugs: clonidine, xylazine, medetomidine, detomidine
reversal: yohimbine, atopamezole, tolazoline
how does NE effect beta 1 receptors
increases cAMP= stimulates contraction of cardiac, conduction and secretion
* heart: SA and AV have beta 1 receptor= increases conduction= ↑heart rate= ↑CO
* heart contractile muscles also have beta 1 receptors= ↑ contractility= ↑SV= ↑Cardiac output
* kidney juxtaglomerular cells= ↑ renin which leads to RAAS = ↑BP
how does NE effect B2 receptors
increases cAMP= inhibit or decrease contraction= induce relaxation
* B2 on blood vessels that supply heart and skeletal muscles: vasodilation= ↓SVR= ↑blood flow to ❤️ and muscle which ↓BP
* smooth muscle on bronchioles= brocho dilation
* liver: ↑ BG by making glucose and breaking down glycogen
* pancrease alpha cells: ↑ glucagon which ↑ BG
* uterus: inhibit uterine contraction by relaxing smooth muscle
NE likes to bind to — and epi likes to bind to —
NE: alpha
EPI: beta
how does sympathatic effects beta 3 receptors
sympa= NE and EPI= flight or flight
* bladder: inhibits detrussor muscle= inhibits urination
what do alpha 1 agonists do and what is one potential side effect
causes contraction
* vasoconstriction arteries= ↑ SVR = ↑BP
* also constricts veins= pushes more blood to heart = ↑ venous return = ↑SV = ↑CO = ↑BP
* constricts pupil muscle= pupils dilate
* reduce bloodflow which can reduce secretions (bloody nose)
phenylephrine
* treat shock leading to hypotension
* dilate pupil
* can cause reflex bradycardia because rapid ↑ in BP will cause baroreceptors to tell brain to produce AcH which will tell HR to drop
what do alpha 2 agonists do
they act as sympatholytics: they inhibit the NE release from NE neurons
* CNS: can cause sedation: by decreasing NE use in the brain
* lungs: ↓ RR
* heart: ↓HR and ↓contractility= ↓CO
* vessels: ↓SVR = ↓BP
aphla 2 drugs: clonidine, xylazine, medetomidine, detomidine
reversal: yohimbine, atopamezole, tolazoline
what do beta 1 agonist do
- heart SA and AV node: increase conduction= ↑HR
- heart muscle: increase contractility= ↑SV= ↑CO
dobutamine
how does dobutamine work
beta adrenergic inotrope- does not cause the release of NE
* mild chronotropic, arrhythmogenic and vasodilation, at higher doses can cause ↑HR
* use to treat bradycardia and CHF
beta 1 agonist:
* ↑HR and ↑contractility/↑CO
some beta 2 and alpha 1
how do beta 2 agonists work
dilation
* lungs: brochodilation
* uterus: relax/inhibit urterine contractions
* albuterol can also works on Na/K pump and causes K into cells
* liver: increase making glucose and breaking down glycogen= ↑BG
* pancreas: increase glucagon= ↑BG
albuterol: short acting B2 agonist
adrenerdic receptors are receptive to
Adrenaline
* EPI
* NE
* alpha and beta receptors
neomycin is what drug class that is poorly absorbed from the GI tract
aminoglycoside (antibiotic)
supportive care
which cats have type A blood vs type B
— antibiotic can cause esophageal strictures in cats and should be given with water
doxycycline