fatty acid synthesis Flashcards by Mindi Kvaal Anderson | Brainscape

Q

acetyl CoA + oxaloacetate =

A

citrate

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Q

cleaves citrate

A

citrate lyase

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Q

purpose of pyruvate malate cycle

A

get 2 C out of mitochondria

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Q

activates acetyl CoA carboxylase

A

citrate, insulin, and xylose 5-phosphate

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Q

inhibits AcetylCOa Carboxylase

A

PalmCoA, AMP-PK, glucagon

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Q

fa synthesis order

A

bond formation, reduction, dehydration, reduction

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Q

enzyme in fa synthesis

A

fa synthase

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Q

drives citrate into fa synthesis

A

high NADH

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Q

sulfur groups of fa synthase

A

cysteine and phosphopantetheinyl

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Q

limit of fa synthesis

A

16 - palmitate

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Q

fa’s are packed together as these

A

TAG, glycerophospolipids, ether phospholipids, spingolipids

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Q

TAG composition

A

glycerol 3-phosphate + 3 FA

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Q

TAG packed with this and released into blood

A

VLDL

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Q

clip fa off VLDL

A

LPL- lipoprotein lipase

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Q

cell membrance lipids, signaling

A

glycerophospholipids - PIP2

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Q

myelin sheath lipid

A

ether glycerolipids

Q

lung surfactant

A

sphingolipids

Q

peptide hormone that surpress appetite

A

leptin

Q

peptide that inhibits FA synthesis

A

adiponectin

Q

rate limiting step of FA synthesis

A

Acetyl CoA –> Malonyl CoA, enzyme Acetyl-CoA carboxylase

Q

cofactor of ACetyl CoA –> Malonyl CoA

A

biotin