Fatigue Flashcards

1
Q

What is a sleep cause of fatigue?

A

Obstructive sleep apnea

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2
Q

What are some an endocrine causes of fatigue?

A
Hypothyroidism 
Adrenal insufficiency 
Hypercalcemia 
Hyper and hypo glycemia 
DM
Cushings
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3
Q

Which infections are known to cause fatigue?

A

HIV, TB, Hepatitis, endocarditis, EBV (rarely)

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4
Q

What is a cardio/pulmonary cause?

A

Congestive heart failure

COPD

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5
Q

What is breakaway weakness?

A

On confrontational testing, full power can be generated only for a brief period before the patient suddenly gives way to the examiner

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6
Q

What is fatiguability weakness?

A

Weakness with repeated evaluation

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7
Q

What does fatigable weakness indicate?

A

A problem of neuromuscular transmission

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8
Q

What causes fatigue in polycythemia Vera?

A

Hyperviscosity and cytokines

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9
Q

What causes fatigue in myelofibrosis?

A

Cytokines release and splenomegaly

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10
Q

What does performance status measure?

A

The extent of the patients disability

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11
Q

What does a performance status grade of 0 indicate?

Grade of 5?

A

Fully active, able to carry on all performances without restriction

5 = death

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12
Q

How to treat fatigue?

A

Treat underlying illness

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13
Q

What test do you order if you suspect anemia?

A

Reticulocyte count

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14
Q

What are the lab features of iron deficiency anemia?

A

Decreased serum iron and ferritin

Increased TIBC

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15
Q

What is the mcc of hemolytic anemia in the world?

A

Malaria

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16
Q

What is pacophagia?

A

A craving for ice chips

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17
Q

How do you treat immune mediated hemolytic anemia?

A

Steroids

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17
Q

Symptoms of facial rubor, headache, dizziness, blurred vision, heaviness in arms or legs, pruritus with hot shower or bath indicate?

A

Polycythemia Vera

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17
Q

Polycythemia is associated with what congestive disorder?

A

Budd chiari syndrome

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17
Q

What mutation causes polycythemia Vera?

A

Jak2K

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17
Q

What is the treatment of PCV?

A

Phlebotomy

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22
Q

How do you treat immune mediated hemolytic anemia?

A

Steroids

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23
Q

Symptoms of facial rubor, headache, dizziness, blurred vision, heaviness in arms or legs, pruritus with hot shower or bath indicate?

A

Polycythemia Vera

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24
Q

Polycythemia is associated with what congestive disorder?

A

Budd chiari syndrome

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25
Q

What mutation causes polycythemia Vera?

A

Jak2K

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26
Q

What is the treatment of PCV?

A

Phlebotomy

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27
Q

How do you treat immune mediated hemolytic anemia?

A

Steroids

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28
Q

Symptoms of facial rubor, headache, dizziness, blurred vision, heaviness in arms or legs, pruritus with hot shower or bath indicate?

A

Polycythemia Vera

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29
Q

Polycythemia is associated with what congestive disorder?

A

Budd chiari syndrome

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30
Q

What mutation causes polycythemia Vera?

A

Jak2K

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31
Q

What is the treatment of PCV?

A

Phlebotomy

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32
Q

How do you treat immune mediated hemolytic anemia?

A

Steroids

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33
Q

Symptoms of facial rubor, headache, dizziness, blurred vision, heaviness in arms or legs, pruritus with hot shower or bath indicate?

A

Polycythemia Vera

34
Q

Polycythemia is associated with what congestive disorder?

A

Budd chiari syndrome

35
Q

What mutation causes polycythemia Vera?

A

Jak2K

36
Q

What is the treatment of PCV?

A

Phlebotomy

37
Q

How do you treat immune mediated hemolytic anemia?

A

Steroids

38
Q

Symptoms of facial rubor, headache, dizziness, blurred vision, heaviness in arms or legs, pruritus with hot shower or bath indicate?

A

Polycythemia Vera

39
Q

Polycythemia is associated with what congestive disorder?

A

Budd chiari syndrome

40
Q

What mutation causes polycythemia Vera?

A

Jak2K

41
Q

What is the treatment of PCV?

A

Phlebotomy

42
Q

How do you treat immune mediated hemolytic anemia?

A

Steroids

43
Q

Symptoms of facial rubor, headache, dizziness, blurred vision, heaviness in arms or legs, pruritus with hot shower or bath indicate?

A

Polycythemia Vera

44
Q

Polycythemia is associated with what congestive disorder?

A

Budd chiari syndrome

45
Q

What mutation causes polycythemia Vera?

A

Jak2K

46
Q

What is the treatment of PCV?

A

Phlebotomy

47
Q

How do you treat immune mediated hemolytic anemia?

A

Steroids

48
Q

Symptoms of facial rubor, headache, dizziness, blurred vision, heaviness in arms or legs, pruritus with hot shower or bath indicate?

A

Polycythemia Vera

49
Q

Polycythemia is associated with what congestive disorder?

A

Budd chiari syndrome

50
Q

What mutation causes polycythemia Vera?

A

Jak2K

51
Q

What is the treatment of PCV?

A

Phlebotomy

52
Q

How do you treat immune mediated hemolytic anemia?

A

Steroids

53
Q

Symptoms of facial rubor, headache, dizziness, blurred vision, heaviness in arms or legs, pruritus with hot shower or bath indicate?

A

Polycythemia Vera

54
Q

Polycythemia is associated with what congestive disorder?

A

Budd chiari syndrome

55
Q

What mutation causes polycythemia Vera?

A

Jak2K

56
Q

What is the treatment of PCV?

A

Phlebotomy

57
Q

How do you treat immune mediated hemolytic anemia?

A

Steroids

58
Q

Symptoms of facial rubor, headache, dizziness, blurred vision, heaviness in arms or legs, pruritus with hot shower or bath indicate?

A

Polycythemia Vera

59
Q

Polycythemia is associated with what congestive disorder?

A

Budd chiari syndrome

60
Q

What mutation causes polycythemia Vera?

A

Jak2K

61
Q

What is the treatment of PCV?

A

Phlebotomy

62
Q

How do you treat immune mediated hemolytic anemia?

A

Steroids

63
Q

Symptoms of facial rubor, headache, dizziness, blurred vision, heaviness in arms or legs, pruritus with hot shower or bath indicate?

A

Polycythemia Vera

64
Q

Polycythemia is associated with what congestive disorder?

A

Budd chiari syndrome

65
Q

What mutation causes polycythemia Vera?

A

Jak2K

66
Q

What is the treatment of PCV?

A

Phlebotomy

67
Q

How do you treat immune mediated hemolytic anemia?

A

Steroids

68
Q

Symptoms of facial rubor, headache, dizziness, blurred vision, heaviness in arms or legs, pruritus with hot shower or bath indicate?

A

Polycythemia Vera

69
Q

Polycythemia is associated with what congestive disorder?

A

Budd chiari syndrome

70
Q

What mutation causes polycythemia Vera?

A

Jak2K

71
Q

What is the treatment of PCV?

A

Phlebotomy

72
Q

How do you treat immune mediated hemolytic anemia?

A

Steroids

73
Q

Symptoms of facial rubor, headache, dizziness, blurred vision, heaviness in arms or legs, pruritus with hot shower or bath indicate?

A

Polycythemia Vera

74
Q

Polycythemia is associated with what congestive disorder?

A

Budd chiari syndrome

75
Q

What mutation causes polycythemia Vera?

A

Jak2K

76
Q

What is the treatment of PCV?

A

Phlebotomy

77
Q

How do you treat immune mediated hemolytic anemia?

A

Steroids

78
Q

Symptoms of facial rubor, headache, dizziness, blurred vision, heaviness in arms or legs, pruritus with hot shower or bath indicate?

A

Polycythemia Vera

79
Q

Polycythemia is associated with what congestive disorder?

A

Budd chiari syndrome

80
Q

What mutation causes polycythemia Vera?

A

Jak2K

81
Q

What is the treatment of PCV?

A

Phlebotomy