Fatigue Flashcards
What is a sleep cause of fatigue?
Obstructive sleep apnea
What are some an endocrine causes of fatigue?
Hypothyroidism Adrenal insufficiency Hypercalcemia Hyper and hypo glycemia DM Cushings
Which infections are known to cause fatigue?
HIV, TB, Hepatitis, endocarditis, EBV (rarely)
What is a cardio/pulmonary cause?
Congestive heart failure
COPD
What is breakaway weakness?
On confrontational testing, full power can be generated only for a brief period before the patient suddenly gives way to the examiner
What is fatiguability weakness?
Weakness with repeated evaluation
What does fatigable weakness indicate?
A problem of neuromuscular transmission
What causes fatigue in polycythemia Vera?
Hyperviscosity and cytokines
What causes fatigue in myelofibrosis?
Cytokines release and splenomegaly
What does performance status measure?
The extent of the patients disability
What does a performance status grade of 0 indicate?
Grade of 5?
Fully active, able to carry on all performances without restriction
5 = death
How to treat fatigue?
Treat underlying illness
What test do you order if you suspect anemia?
Reticulocyte count
What are the lab features of iron deficiency anemia?
Decreased serum iron and ferritin
Increased TIBC
What is the mcc of hemolytic anemia in the world?
Malaria
What is pacophagia?
A craving for ice chips
How do you treat immune mediated hemolytic anemia?
Steroids
Symptoms of facial rubor, headache, dizziness, blurred vision, heaviness in arms or legs, pruritus with hot shower or bath indicate?
Polycythemia Vera
Polycythemia is associated with what congestive disorder?
Budd chiari syndrome
What mutation causes polycythemia Vera?
Jak2K
What is the treatment of PCV?
Phlebotomy
How do you treat immune mediated hemolytic anemia?
Steroids
Symptoms of facial rubor, headache, dizziness, blurred vision, heaviness in arms or legs, pruritus with hot shower or bath indicate?
Polycythemia Vera
Polycythemia is associated with what congestive disorder?
Budd chiari syndrome
What mutation causes polycythemia Vera?
Jak2K
What is the treatment of PCV?
Phlebotomy
How do you treat immune mediated hemolytic anemia?
Steroids
Symptoms of facial rubor, headache, dizziness, blurred vision, heaviness in arms or legs, pruritus with hot shower or bath indicate?
Polycythemia Vera
Polycythemia is associated with what congestive disorder?
Budd chiari syndrome
What mutation causes polycythemia Vera?
Jak2K
What is the treatment of PCV?
Phlebotomy
How do you treat immune mediated hemolytic anemia?
Steroids