Clinical Manifestations And Fever Flashcards
What skin infection is described by a superficial skin infection with well defined borders
Erysipelas
What is a skin infection described by deeper skin infection involving the dermis and sub cutaneous fat?
Cellulitis
What is the most common cause of bacterial pharyngitis in children or adolescents ?
GAS; strep pyogenes
What are some risk factors for reactivating of TB?
Gastrectomy Silicosis DM HIV Immunosuppressive drugs
Which four cutaneous conditions are highly suggestive of HIV infection?
Hairy leukoplakia of the tongue
Disseminated kaposi sarcoma
Cutaneous bacillary angiomatosis
Generalized lymphadenopathy
What are some opportunistic infections in AIDS (AIDS defining illness) ?
Pneumocystis jirovecii Kaposi/HHV8 CMV EBV Histoplasmosis Coccidoidmycosis Crytpcoccosis Mycobacterium tuberculosis
What is seen in CMV in immunocompromised ?
CMV retinitis Esophagitis Small bowel inflammation Colitis Pneumonia is Neuro manifestations
What is caused by Exposure to bird and bat droppings ?
Histoplasmosis
What does histoplasmosis present like?
Influenza like illness, atypical pneumonia
Fever, cough
Who is affected by disseminated histoplasmosis ?
Immunocompromised
Disseminated HIV infected patients present how? **
With miliary infiltrates, lymphadenopathy and meningitis but skin lesions are uncommon
Which plasmodium is responsible for nearly all severe disease?
P. Falciparum
Which plasmodium is responsible for the 48 hour cycles of fever?
P vivax and p ovale
Which plasmodium causes 72 hour cycles of fever?
P malarial
Waldenstrom macroglobulinemia is similar to multiple myeloma except how?
Absence of lyric bone lesions
The sx of anemia, bone pain, tenderness, lyric bone lesions, kidney failure, spinal cord compression, neuropathy, soft tissue masses and increased susceptibility to infection indicate what?
Multiple myeloma
what are some clinical manifestation of sepsis ?
Hypotension Fever Tachycardia Tachypnea Warm flushed skin at first, then cool Decreased capillary refill Altered mental status Obtunded Absent bowel sounds
What lab values are found in sepsis?
Leukocytosis >12,000 Or leukopenia <4000 Hyperglycemia >140 glucose CRP Hypoxemia Oliguria (urine output <0.5 per hour) Creatinine >0.5 mg/dL
INR >1.5 A aPTT >60 Platelets <100,000 Bilirubin >4mg/dl Hyperlactatemia >2 mmol/L
What causes bacteremia? (5)
Skin and soft tissue infections Central venous catheters Bone and joint infections Pneumonia Endocarditis
Diabetic foot ulcer infections are commonly caused by what bug?
MRSA
What’s the most common strep pathogen in adults?
GBS; strep agalactiae
Pandemics are usually due to which type of influenza?
Influenza A
GI symptoms may occur in which type of influenza ?
Influenza B
What are the three modes of transmission for HIV?
Sexual contact w infected person
Parenteral exposure to infected blood by needle sharing or transfusion
Perinatal exposure