Fat Soluble Vitamins Flashcards

1
Q

Fat Soluble Vitamins
Is Found in ——– in association with lipids.

A

feedstuffs

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2
Q

FSV is Absorbed in the —- in association with lipids.

A

diet

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3
Q

FSV Usually involved in the regulation of ———- of the body (—— and ——)

A

structural portion

Muscles bones

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4
Q

Moderate to extensive storage time in —— (——- and ——, —–, ——, and —- —–)

A

Tissues
kidney and liver, muscles,
brain and fat tissue).

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5
Q

FSV is Usually exist in nature as

A

precursor

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6
Q

FSV is Relatively sensitive to ——, heat, UV light, —– —- and
specific ——.

A

oxidation
metal ions
enzymes

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7
Q

The ——- —– ——- is the most
widely distributed and
most active precursor of
vitamin A; converted to
active form in the —– and ——-

A

carotenoid beta-carotene
liver and intestine.

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8
Q

Active forms of Vitamin A

A

Retinol, Retinal, and Retinaldehyde

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9
Q

Functions:
• Normal development of various —— —— in the body
• Formation of visual purple (———-) for dim light vision
• Formation of —– and —–
• Control of growth and differentiation processes of the cellular metabolism by influencing the transcription of —– —– —- genes.
• Increase resistance to —— ——
• Antioxidative effect on cell degrading lipid radicals, resulting in
——— —– —–
(FSH and LH)

A

Vitamin A

epithelial tissues
(rhodopsin)
bones and collagen
infectious diseases.
increased hormonal activity

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10
Q

Sources of Vit. A
• In the form of its precursor carotene, vitamin A is found in ——, y——– and —– plants
• L—-, k—–, b——– c——- and e– —— are also rich in vitamin A.

A

carrot,
yellow maize and green plants.
Liver, kidney, butermilk, codliver oil and egg youl

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11
Q

Deficiency symptoms:
• Pneumonia
• Poor fertility or abortions
• Paralysis
• Night blindness
• Xerophthalmia
• Susceptibility of young to diseases.

A

Vitamin A

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12
Q

Hypervitaminosis of Vit A

A

Hyperostosis, hyperkeratosis

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13
Q

Is sensitive to heat and light

A

Vitamin A

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14
Q

Known as antirachitic factor, a group of closely related compounds that
possess antirachitic activity which may be supplied through the diet or
by irradiation of the body through sunlight exposure (hence “——– ——)

A

Vitamin D
(“sunshine vitamin”)

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15
Q

Two most prominent forms of Vit. D

A

Ergocalciferol (D2)
Cholecalciferol (D3)

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16
Q

Ergocalciferol (D2) derived from a common plant steroid
precursor

A

ergosterol

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17
Q

Cholecalciferol (D3) derived from precursor ————–
exclusively from animal products

A

7-dehydrocholesterol

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18
Q

Precursors of vit D have – ——– ——–.

A

no antirachitic activity

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19
Q

are able to convert vitamin D2
to vitamin D3

A

Four-legged animals (i.e. cattle, swine, horses, sheep, goats, etc.)

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20
Q

are not able to efficiently convert vitamin D2 to vitamin D3.

A

Poultry

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21
Q

is the primary form of vitamin D in poultry rations.

A

Vit. D3

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22
Q

• For all species, efficiency of utilization is greater for
——– as
compared to ——–.

A

vitamin D3;vitamin D2

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23
Q

The metabolically active form of vitamin D

A

1,25 dihydroxycholecalciferol
(1, 25-(OH)2-D3) or calcitriol.

24
Q

Calcitriol is synthesized with the addition of one hydroxyl group in the
—– and one hydroxyl group in the —– of the animal.

A

Liver and kidney

25
Q

C28H44O

A

Ergocalciferol

26
Q

C27H44O

A

Cholecalciferol

27
Q

Functions:
• Absorption of —— through the intestinal wall.
• Regulates formation of a compound known as —— —— —–
• Involved in bone metabolism.
• Controls transcription of more than .
• Promotes germ cell production.

A

Vitamin D
Calcium
calcium binding protein.
50 genes

28
Q

Functions:
• Absorption of calcium through the intestinal wall.
• Regulates formation of a compound known as —— —— —–
• Involved in bone metabolism.
• Controls transcription of more than 50 genes.
• Promotes germ cell production.

A

Vitamin D

calcium binding
protein.

29
Q

Deficiency Symptoms of Vit. D

A

Rickets and Osteomalacia

30
Q

disturbance of normal ossification in young animals characterized by a decreased Ca and P in the organic matrices
of cartilage and bone;

A

Rickets

31
Q

signs include enlarged junction between bone and cartilages, curvature of the bones, tendency to drag hind legs, beaded ribs, deformed thorax and weakening of muscular tissue and susceptibility to infection.

A

Rickets

32
Q

adult form of rickets; decreased Ca and P in
the organic matrices leading to an easily broken bones.

A

Osteomalacia

33
Q

In poultry a deficiency of vitamin D causes the bone
and beak to become —– and —— growth is usually retarded and the legs may become bowed, ruffled feathers. Egg production is reduced and egg
quality deteriorates.

A

soft and rubbery,

34
Q

Hypervitaminosis of Vit. D

A

Calcinosis

35
Q

diffuse soft tissue calcification affecting, among others, the cardiovascular and respiratory
tracts.

A

Calcinosis

36
Q

are favorable sources of vitamin
D.

A

Sun cured forages and fish oils

37
Q

Irradiated animal sterols and fish products contain

A

Vit. D3

38
Q

Irradiated yeast and plant products

A

Vit. D2

39
Q

Examples of Vit. E

A

Tocopherols and Tocotrienols

40
Q

is the most biologically
active and most widely distributed Vit. E

A

a-tocopherol

41
Q

Functions:
• Maintains proper permeability of the ——– —–.
• Development of proper —- structure.
• Serves as an ——– (phospholipids in the cell membrane).
• There is close relationship in the functions of vitamin E and selenium in protecting the ———— from oxidation.
• Reduces the production of —– —— —— from highly unsaturated
fatty acids.
• Antitoxic effect in cell metabolism.
• Stabilization of fat in ——– (meat, milk, eggs).

A

Vit. E

Capillary walls
Muscle
antioxidant
cell membrane
Lipid peroxy radicals
animal products

42
Q

Sources:
• Cereal grains, especially the —- and —- —— , and cereal products
• —— and in general green plants
• ——- ———- are relatively poor sources of the vitamin E

A

Vitamin E
oil and germ portions,
Legumes
Animal products

43
Q

Vit. E

In nature, its synthesis is a function of ——- and thus their products are
by far the principal sources

A

plants

44
Q

The vit E deficiency symptoms in farm animals are —— ——– (——–)

A

muscle degeneration (myopathy).

45
Q

in cattle, goat and sheep affects the skeletal muscles, which is manifested
by difficulty in standing, trembling and staggering gait.

A

Nutritional Myopathy (muscular dystrophy or white muscle disease)

46
Q

In pigs vitamin E deficiency diseases are —— and cardiac disease known as ——— ——- ——
(hemorrhagic lesions within the heart
that gives characteristic ‘mulberry‘ appearance) and ——- ——— (toxic liver dystrophy)

A

Myopathy
Mulberry heart disease
hepatosis dietetica

47
Q

In poultry, Vit. E deficiency causes the following:

a. : It is characterized by edema, blackening of affected part, apathy and inappetance.

b. characterized by ataxia, head retraction and cycling with legs.
c.

A

Exudative diathesis
Nutritional Encephalomalacia (crazy chick disease)
Muscular Dystrophy

48
Q

Hypervitaminosis of Vit. E

A

Vit. E is not toxic even at higher dose

49
Q

A group of quinone compounds that have characteristic antihemorrhagic effect

A

Vitamin K

50
Q

is the basic molecule of Vit. K and the following are the various isomers:
a. – extracted from plant materials
b. – synthesized in the liver or by microbes in the gut
c.
– simplest form; an industrial form

A

Napthoquinone

Phyloquinone (K1)
Menaquinone (K2)
Menadione (K3)

51
Q

Functions:
• Required for the maintenance of normal levels of blood clotting factors II (———) VII (————), IX (———-) and X (——– —— —– ), all of which are synthesized in the —– (synthesis of
prothrombin).

A

Vitamin K

Prothrombin
Proconvertin
Christmas Factor
Stuart-prower factor

Liver

52
Q

Functions:

Participation in the ———– of other proteins.
• Production of the calcium transport protein ——— for bone
mineralization.

A

Vit. K

Carboxylation
osteocalcin

53
Q

Sources:
• Major sources of K1 are
• K2 by/from
• K3 is offered in various —— ——– menadione compounds for
animal nutrition

A

plant sources (fresh dark green vegetables)
bacterial flora
water-soluble

54
Q

Deficiency symptoms of Vit. K

• Prolonged ———- or impairment of
• Multiple ——– (subcutaneous and
internal) can also occur and can be fatal

A

clotting time; blood coagulation
hemorrhages

55
Q

Hypervitaminosis of Vit K:

• Excessive intake of K3 may result to
growth ——-, ——-, m————-

A

depression, anemia,
methemoglobinemia