Farm urinary Flashcards
Normal cow urinalysis?
SG 1.020-1.045
pH normally alkaline
Protein - usually trace only
Glucose - usually trace
Clinical signs of urinary disease?
Abdominal pain - pyelonephritis, calculi
Dysuria - pyelonephritis, calculi, cystitis, (vaginitis)
Haematuria +/- pus +/- calculi
Polyuria - DM (post FMD), diabetes inspires, idiopathic (calves)
Anuria - construction by calculi
Oliguria - prerenal, renal or post renal
Proteinuria - renal amyloidosis - breed
Causes of haematuria?
Pyelonephritis (+pus) Cystitis Urolithiasis Enzootic haematuria Acute bracken poisoning Toxic nephrosis (acorn) Glomerulonephritis, renal infarction etc
Causes of haemoglobinuria?
Babesiosis (red water)
Post parturient haemoglobinuria
Bacillary haemoglobinuria (Clostridium haemoliticum)
What is hypospadia?
Failure of closure of male urethra
Usually fatten fine
Scalding - welfare issue, daily hosing
Pyelonephritis - Most common cause in cows? Which cows? Sings? Treatment?
Corynebacterium renale and E.coli
Usually sporadic
More common in suckler cows - venereal spread by natural service?
Secondary to trauma e.g. dystocia
Signs:
- chronic weight loss
- +/- mild pyrexia
- appetite usually ok
- dysuria
- blood and pus in urine (pus on vulval hairs)
- per rectum exam: swollen painful kidney, bladder and ureteral involvement and thickening
Treatment:
- long course antibiotics
- C renal sensitive to most (penicillins, oxytetracycline)
- E.coli isn’t (amoxicillin/clavulonic acid)
1/3 get better, 1/3 recur, 1/3 never get better
Cystitis - When seen? Signs? Treatment?
Often associated with pyelonephritis
Secondary to dystocia - ascending infection
Similar signs to pyelonephritis:
- chronic weight loss
- +/- mild pyrexia
- appetite usually ok
- dysuria
- blood and pus in urine (pus on vulval hairs)
- per rectum exam: swollen painful kidney, bladder and ureteral involvement and thickening
- straining more pronounced
Treatment:
- long course antibiotics
- organism and sensitivity less predictable than pyelonephritis
What is amyloidosis? Signs?
Deposition of amyloid and Ab/Ag complexes Secondary to other chronic infections (can be primary) Signs: - off food and ill - profuse diarrhoea - generalised s/c oedema - PUPD - proteinuria - low plasma albumin - pale swollen kidneys
What is enzootic haematuria? Causes? Signs?
Haemangiomata in bladder
Associated with long term ingestion of bracken
Older cows
Other causes - “tear pastures”, high molybdenum
Blood clots in urine
Tumours in guts - SCC
What specific conditions does bracken cause in cattle, horses and sheep?
Contains a thiamine - toxic in horses (and pigs - heart enlargement?) but no effect in ruminants
Bright blindness - sheep retinal atrophy
Enzootic haematuria - long term ingestion
Gut tumours - sheep and cattle, long term ingestion
Bladder wall tumours
Haemorrhagic syndrome (blood in faeces, urine and haemorrhages on mucous membranes)
General clinical signs of bracken poisoning?
Bone marrow toxicity Pancytopenia and thrombocytopenia Petechiae in mouth, conjunctiva, vulva etc S/C bruising Blood clots - nose, faeces Pyrexia Depression Weakness Anorexia Diarrhoea (bloody) Death
What causes toxic nephrosis in cattle? Clinical signs? Diagnosis? Treatment?
Oak (acorn) poisoning (phenols and tannins) on pastures 3-5d after autumn storms
Tannins in acorns cause kidney damage
Sudden death
Anorexia, depression, bloat due to luminal stasis
Colic
Anorexia
Weight loss
Ascites
Oedema
Haematuria
Constipation and straining, progressing to fetid black tarry diarrhoea
Bloods - raised urea and creatinine, raised liver enzymes
PME - GIT ulceration and haemorrhage, nephritis, liver degeneration
Death in 4-7d despite supportive treatment?
Pigs more resistant
What causes Bacillary haemoglobinuria? Signs? Prevention?
Uncommon - wet, high pH pastures in SW Clostridium haemolyticum - toxins In soil and dormant in liver Migrating fluke - trigger spores Pyrexia, jaundice, anaemia, oedema, Hburia Fatal Vaccinate (Black disease), fluke control
What causes red water? Spread? Signs? Which animals? When? Clinical signs?
Babesia divergens in UK
Tick borne - Ixodes ricinus, Haemaphyllis punctata
Also trans ovarian transmission
Clinical signs in older non immune animals
Premunity results from infection when young - inverse age immunity
Spring and autumn rise
Rented grazing = novel exposure
Signs:
- pyrexia
- anaemia and Hburia “port wine urine”
- diarrhoea
- later constipation, low temperature, anaemia, jaundice
Diagnosis and treatment of babesiosis/red water? Immunity?
Blood smear - capillary blood from ear, parasites in RBC, evidence of anaemia
ELISA to assess herd exposure
Treatment:
- imidocarb licensed (213d meat, 21d milk withhold)
- 1ml/100kg curative
- 2.5ml/100kg
- toxic at 1.75 x dose, death at 5 x dose
- preventative immunity depends on adequate challenge by infected ticks during treatment period
- supportive therapy: blood transfusion, fluids
Post parturient haemoglobinuria - seen in which animals? When? Cause? Clinical signs? Treatment?
Uncommon - older high yielding dairy cows Sporadic cases 1-4 weeks after calving? Cause: - low phosphorous diet - kale, rape, turnips etc Signs: - sudden onset - hamoglobinuria - pallor, jaundice - collapse, dyspnoea - death Treatment: - guarded prognosis - phosphorous (Boston injection) - blood transfusion
How to do a blood transfusion for a cow?
One transfusion is safe without cross matching
Sodium nitrate (anti-coagulant) - 10ml of 3.85% solution per 100ml blood
Choke-Rope around neck to raise jugular
Jugular trochar or 10-12G catheter to collect
5L blood
Collect in Winchester bottle or empty wormer bottle
Aetiology and diagnosis of bracken poisoning in farm animals?
Cyanogenic glycoside, thiaminases
History, clinical signs, blood results
Urolithiasis - Which animals? What are the calculi usually?
2-4mo ram lambs
Mature goats castrated in first few days of life
Bull beef calves
Usually sporadic but can have “outbreaks”
Usually Calcium/magnesium ammonium phosphate
What is urolithiasis associated with in farm animals?
Ca:P imbalance in diet
High concentrate diet
Water deprivation
Interactions like forage quality changing concentrate intake
History of diet change in mature animals
Inappropriate material used in feeds - e.g. pig nuts as source of mineral in goat mix
Signs of urolithiasis?
Restlessness
Abdominal pain (kicking) and straining (hiccups)
Dysuria or anuria - dry floor
Preputial crystals/sand
Progressive til urethra and/or bladder ruptures
Bladder rupture - initially brighter, high urea and creatinine in abdominal fluid, S/C oedema - water belly
Diagnosis of urolithiasis/urethral/bladder rupture?
Abdominal palpation: - distended bladder - free fluid wave - s/c fluid: pitting, colour of skin (location indicates site of rupture) Hair of ventral abdomen - "sand around preputial orifice Examine penis (exteriorise): - if cannot exteriorise then cut down into middle of prepuce Radiography US better: - s/c tissue - free fluid in abdomen - bladder - kidney: cortex/medulla reatio Abdominocentesis - s/c guided, sample s/c fluid too Palpate urethra per rectum - if calculi palpable, no point doing anything more distal Blood sample: - urea, creatinine - potassium - PCV - TP
Treatment of urolithiasis?
Relaxants (buscopan or xylazine) always used but of little use - xylazine will either make better if flushes blockage or will make worse as diuresis
Casualty slaughter - unlikely to pass inspection as uraemic
Surgery:
- start by exteriorising end of penis (in castrated goat: sedate, LA, forceps into prepuce, cut down midway to exteriorise)
- palpate to feel if calculi
- maybe catheterise urethra (carved catheter and guide)
- percutaneous bladder cathetarisation: care with entrapping viscera
- if bladder ruptured and cannot be cathetarised: GA, laparotomy, repair bladder, or tube cystotomy
- flush with 10% Walpole’s solution in saline