Fanselow And Dong 2010

Question 1

According to Fanselow and Dong (2010), describe role/findings involving dorsal hippocampus

Answer 1

Broadly, retrieval of spatial memory.
DH lesions- impaired spatial memory during radial area maze (rats forget how to return to location previously paired with food)
Dorsal/septal pole of hippocampus- memory function

Cognitive learning, memory associated with navigation, exploration, locomotion.

Gene expression findings suggest that DH correlates with cortical regions involved in info processing.

Question 2

According to Fanselow and dong (2010), describe role/findings involving the ventral hippocampus:

Answer 2

Ventral/temporal pole - emotional and affective processes
VH and adjacent posterior amygdala project to ventrolateral septum and anteriomedial nuclei of BNST (BNST–> hypothalamic motoneuron pool, direct projections to Paraventricular nucleus)

Gene expression in ventral hippocampus correlates with gene expression in regions of amygdala, hippocampus (Emo/stress regions)