Dos Santos & Brandao 2011 Flashcards

1
Q

Dos Santos & Brandao 2011 method

A

Injections of muscimol (GABA A agonist) and semicarbazide (act to decrease available GABA) into anterior hypothalamic nucleus or dorsomdeial portion of ventromedial nucleus

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2
Q

Dos Santos & Brandao 2011 findings

A

Muscimol injections into the anterior hypothalamic nucleus or dorsomedial portion of ventromedial hypothalamic nucleus resulted in reduced conditioned freezing in response to a light-conditioned stimulus
Semicarbazide injections in the anterior hypothalamic nucleus had the opposite effect. Semicarbazide injection in dm portion of vm hypothalamic nucleus had no impact on freezing to light conditioned stimulus.

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3
Q

Dos santos & Brandao (2011)- what is the defensive hypothalamic area? What NT is it under the influence of? What 4 components make up the DHA?

A

DHA integrates INNATE responses to environmental threats and is under tonic GABAergic (inhibitory) control. The DHA includes:
Anterior hypothalamic nucleus
Dorsomedial portion of ventromedial nucleus
Dorsomedial hypothalamus
Dorsal pre mammillary nucleus

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