Face And Palate Flashcards
When do pharyngeal arches start to form
4th week as neural crest cells start to migrate
What does the pharyngeal arch contain
Mesenchyme, myoblast, nerve, artery, cartilage
First pharyngeal arch
Trigeminal nerve. Muscles of mastication. Tensor palatini and tensor tympani. Anterior digastric. Mylohyoid. Meckel’s cartilage. Malleus and incus. Pouch gives rise to external auditory canal and tympanic membrane
Second pharyngeal arch
Facial nerve. Muscles of facial expression. Posterior digastric. Stylohyoid. Stapedius. Reichert’s cartilage. Hyoid bone lesser horn and upper body. Pouch form palatine tonsil crypt.
Third pharyngeal arch
Stylopharyngeus. Glossopharyngeal nerve. Hyoid bone greater horn, inferior body. Pouch give rise to thymus and inferior parathyroid
Fourth pharyngeal arch
Vagus nerve. Muscles of soft palate (tensor palatini, levator palatini, palatoglossus, palatopharyngeus, uvula muscle), pharynx and larynx. Thyroid, cricoid, arytenoid cartilage. Pouch is thyroid c cells (Calcitonin) and superior parathyroid
Sixth pharyngeal arch
Scm and trapezius. Accessory nerve.
Boundaries of stomodeum
Developing heart at the bottom. Buccopharyngeal membrane at posterior. Frontal prominence on top. First pharyngeal arch on lateral walls
Buccopharyngeal membrane composed of what 2 layers of tissue
Ectoderm and endoderm
What forms the external tissues of the face
Frontonasal prominence and first pharyngeal arch.
Frontonasal prominence is of neural crest origin.
First pharyngeal arch is mesoderm and neural crest in origin
Describe the whole development of the face
4th week:
Nasal placode: bilateral oval shape thickening of ectoderm, lower part of frontonasal prominence. Medial and lateral nasal prominences proliferate, invagination, nasal pit
6th week:
Medial nasal prominence start to fuse towards midline.
Mandibular prominences merge.
Maxillary prominence start to emerge from mandibular prominence.
7th week: (everything else happens)
- medial nasal prominence merge to form intermaxillary segment and filtrum and incisors
- maxillary and medial nasal prominence merge
- maxillary and lateral nasal prominence merge
- medial and lateral nasal prominence merge
Hare lip is
Bilateral cleft lip. Medial and maxillary prominences don’t fuse
Extrinsic factors of elevation of palatal shelf
Nasal septum. Mandible growth spurt. Fetal mouth opening reflex.
Intrinsic forces for movement of palatal shelf
GAGs. Hyaluronic acid. These result in hydration of ECM.
Contraction of mesenchymal cells. Differential proliferation of mesenchymal cells. Change in vascularity