FA Toxicology Flashcards

1
Q

Aspergillus fungi are a source of which mycotoxin?

C/S

A

Aflatoxin

  • Decreased milk yield
  • Decreased feed intake
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2
Q

Claviceps fungi are a source of which mycotoxin?

C/S

A

Ergot

  • Reduced milk yield
  • Hyperthermia
  • Subfertility
  • Dry gangrene of extremities
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3
Q

Fusarium fungi are a source of which Mycotoxins?

C/S

A
  1. Deoxynivalenol (DON)
    1. Decreased VFI
    2. Decreased MY
    3. Diarrhoea
    4. Immune alterations
  2. Zearalenone
    1. Hyperestrogenism
      1. Vulval/ mammary hyperaemia/ swelling
      2. Nymphomania
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4
Q

What clinical signs are associated with Organophosphate intoxication?

A

Cholinesterase inhibitors

  • XS salivation
  • Respiratory signs - discharge, cough, dyspnoea, lacrimation, miosis
  • Muscle stiffness
  • Death
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5
Q

What clinical signs are associated with lead intoxication?

A
  • Neuro/GIT
  • Sudden death
  • Muscle fasciculations
  • Teeth grinding
  • Staggered gait
  • Blindness - pupillary stasis
  • Colic/ ruminal stasis
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6
Q

What clinical signs are associated with copper intoxication?

A
  • Haemolytic crisis
    • anaemia
    • jaundice
    • death <48hrs
  • Hepatomegaly
  • Bronze/black kidney
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7
Q

Pyrrolizidine alkaloid

A

Ragwort

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8
Q

Clinical signs associated with Bracken poisoning.

A
  • Bone marrow suppression
  • Thrombocytopenia
  • Anorexia
  • Despression
  • Dysentery
  • Weakness
  • Petechia/ haematuria
  • Death
  • GI tract tumours
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9
Q

Ptaquiloside

A

Carcinogenic substance found in Bracken

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10
Q

Clinical signs associated with Yew intoxication.

A
  • Cardiac depression
  • Sudden death
  • Dyspnoea
  • Abdominal pain
  • Muscle tremor/weakness
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11
Q

Taxine alkaloid.

A

Yew

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12
Q

Tannins

A

Oak/acorn

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13
Q

Grayanotoxin

A

Rhododendron

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14
Q

Digoxin

A

Fox glove - cardiacglycocide

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15
Q

C/S associated with nitrate intoxication.

A
  • Hyperaemia/ oxygen tension
  • Anoxia
  • Cyanotic mucosa
  • Tachypnoea
  • Weak & rapid pulses
  • Brown discoloured blood
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16
Q

C/S associated with Digoxin intoxication.

A
  • Arrhythmia
  • Bradycardia
  • GI signs
  • Hyperkalaemia
17
Q

C/S associated with Tannin intoxication.

A
  • Nephrotoxicity
  • Anorexia
  • Constipation
  • Bloody diarrhoea
  • Progressive weakness
18
Q

C/S associated with Rhododendron intoxication.

A
  • Salivation
  • Staggered gair
  • Abdominal pain
  • Collapse/ death
  • Vomitting