FA - Pharm - Antidotes Flashcards

1
Q

Acetaminophen

A

N-acetylcysteine

-> replenish glutathione

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2
Q

Salicylates

A

NaHCO3 (sodium bicarb)
-> alkalinizes urine
dialysis

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3
Q

amphetamines (basic)

A

NH4Cl

-> acidify urine

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4
Q

acetylcholinesterase inhibitors

A

atropine, pralidoxine

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5
Q

organophosphates

A

atropine, pralidoxine

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6
Q

antimuscarinic, anticholinergic agents

A

physostigmine salicylate,

controled hyperthermia

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7
Q

beta-blockers

A

glucagon

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8
Q

digitalis

A
KLAM:
normalize K,
Lidocaine,
Anti-dig Fab fragments
Mg 2+
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9
Q

Iron

A

Deferoxamine, deferasirox

Iron = Fe; “fe” in the drug name

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10
Q

Lead

A

CaEDTA
dimercaprol
succimer
penicillamine

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11
Q

Mercury

A

Dimercaprol (BAL)

succimer

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12
Q

Arsenic

A

Dimercaprol (BAL)
succimer
Penicillamine

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13
Q

Gold

A

Dimercaprol (BAL)
succimer
Penicillamine

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14
Q

Copper

A

Penicillamine

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15
Q

Cyanide

A

nitrite + thiosulfate

hydroxocobalamin

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16
Q

Methemoglobin

A

methylene blue

vitamin C

17
Q

Carbon monoxide

A

100% O2

hyperbaric O2

18
Q

Methanol

A

Fomepizole > ethanol

dialysis

19
Q

ethylene glycol (anti-freeze)

A

Fomepizole > ethanol

dialysis

20
Q

opioids

A

naloxone/naltrexone

21
Q

benzodiazepines

A

flumazenil

22
Q

TCAs

A

NaHCO3

-> plasma alkalinization

23
Q

heparin

A

protamine

24
Q

warfarin

A

vitamin K

fresh frozen plasma

25
Q

tPA

A

aminocaproic acid

26
Q

streptokinase

A

aminocaproic acid

27
Q

urokinase

A

aminocaproic acid

28
Q

theophylline

A

beta-blocker