extracellular matrix Flashcards
elastic fibres: recall the definition, function and composition of elastic fibres
1
Q
elastic fibres: property
A
elasticity of tissues (skin, vessels, lungs)
2
Q
what are elastic fibres interwoven with and why
A
collagen to limit stretching extent
3
Q
elastic fibres: structure
A
core of elastin, microfibrils (fibrillin)
4
Q
genetic condition associated with mutation in fibrillin-1
A
Marfan’s syndrome
5
Q
symptoms of Marfan’s syndrome
A
arm span>height, aortic ruptures
6
Q
elastin structure
A
alternating cross-linked hydrophobic and a-helical regions of alanine and lysine; stretch and relax
