Extracellular Matrix Flashcards
Where is the extracellular matrix (ECM) located?
The ECM is located in all tissues and organs providing essential physical support for cellular constituents.
What role does the ECM play in biochemical signals?
The ECM initiates important biochemical and biomechanical signals vital for tissue morphogenesis differentiation
What is the structure of the ECM?
The ECM is a 3D network composed of collagens, proteoglycans, elastin, fibronectin, laminins and other glycoproteins.
How do ECM components interact with cells?
ECM components interact with each other and with cell adhesion receptors to provide structural support for cells in tissues and organs.
How do cell surface receptors interact with the ECM?
Cell surface receptors receive signals from the ECM regulating key functions like cell survival, growth, movement and differentiation.
What is the main function of the ECM?
The ECM surrounds, supports and provides structure to the cell.
How does the ECM contribute to cell communication?
It helps cells attach to and communicate with nearby cells.
What role does the ECM play in cellular functions?
The ECM plays a crucial role in cell growth movement
How is the ECM involved in tissue repair?
It is involved in tissue repair and regeneration.
What can abnormal changes in the ECM contribute to?
Abnormal changes in the ECM can contribute to the development of diseases like cancer.
